Restless Legs Syndrome Prevalence and Impact: REST General Population Study
Richard P. Allen,Arthur S. Walters,Jacques Montplaisir,Wayne A. Hening,Andrew Myers,Timothy J. Bell,Timothy J. Bell,Luigi Ferini-Strambi +7 more
TLDR
Clinically significant RLS is common (prevalence, 2.7%), is underdiagnosed, and significantly affects sleep and quality of life.Abstract:
Background Restless legs syndrome (RLS), a common sensorimotor disorder, has a wide range of severity from merely annoying to affecting sleep and quality of life severely enough to warrant medical treatment. Previous epidemiological studies, however, have failed to determine the prevalence of those with clinically significant RLS symptoms and to examine the life effects and medical experiences of this group. Methods A total of 16 202 adults (aged ≥18 years) were interviewed using validated diagnostic questions to determine the presence, frequency, and severity of RLS symptoms; respondents reporting RLS symptoms were asked about medical diagnoses and the impact of the disorder and completed the Short Form-36 Health Survey (SF-36). Criteria determined by RLS experts for medically significant RLS (frequency at least twice a week, distress at least moderate) defined “RLS sufferers” as a group most likely to warrant medical treatment. Results In all, 15 391 fully completed questionnaires were obtained; in the past year, RLS symptoms of any frequency were reported by 1114 (7.2%). Symptoms occurred at least weekly for 773 respondents (5.0%); they occurred at least 2 times per week and were reported as moderately or severely distressing by 416 (2.7%). Of those 416 (termed RLS sufferers), 337 (81.0%) reported discussing their symptoms with a primary care physician, and only 21 (6.2%) were given a diagnosis of RLS. The SF-36 scores for RLS sufferers were significantly below population norms, matching those of patients with other chronic medical conditions. Conclusion Clinically significant RLS is common (prevalence, 2.7%), is underdiagnosed, and significantly affects sleep and quality of life.read more
Citations
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Restless legs syndrome/Willis-Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria--history, rationale, description, and significance.
Richard P. Allen,Daniel L. Picchietti,Diego Garcia-Borreguero,William G. Ondo,Arthur S. Walters,John W. Winkelman,Marco Zucconi,Raffaele Ferri,Claudia Trenkwalder,Hochang B. Lee +9 more
TL;DR: The IRLSSG consensus criteria for RLS/WED represent an international, interdisciplinary, and collaborative effort intended to improve clinical practice and promote further research.
Journal ArticleDOI
Epidemiology of restless legs syndrome: A synthesis of the literature
TL;DR: Overall, individuals with RLS have a poorer health than non-RLS but evidence for specific disease associations is mixed and future epidemiological studies should focus on systematically adding frequency and severity in the definition of the syndrome in order to minimize the inclusion of cases mimicking RLS.
Journal ArticleDOI
Evidence‐Based Recommendations for the Assessment and Management of Sleep Disorders in Older Persons
Harrison G. Bloom,Harrison G. Bloom,Imran Ahmed,Cathy A. Alessi,Cathy A. Alessi,Sonia Ancoli-Israel,Daniel J. Buysse,Meir H. Kryger,Barbara Phillips,Michael J. Thorpy,Michael J. Thorpy,Michael V. Vitiello,Phyllis C. Zee +12 more
TL;DR: The goals of this article are to help guide clinicians in their general understanding of sleep problems in older persons, examine specific sleep disorders that occur in older Persons, and suggest evidence‐ and expert‐based recommendations for the assessment and treatment of sleep disorders in older people.
Journal ArticleDOI
Association of restless legs syndrome and cardiovascular disease in the Sleep Heart Health Study
TL;DR: Restless legs syndrome (RLS) is associated with prevalent coronary artery disease and cardiovascular disease and this association appears stronger in those with greater frequency or severity of RLS symptoms.
Journal ArticleDOI
Restless Legs Syndrome: Prevalence and Impact in Children and Adolescents—The Peds REST Study
Daniel L. Picchietti,Richard P. Allen,Arthur S. Walters,Julie E. Davidson,Andrew Myers,Luigi Ferini-Strambi +5 more
TL;DR: These population-based data suggest that restless legs syndrome is prevalent and troublesome in children and adolescents, occurring more commonly than epilepsy or diabetes.
References
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Book
SF-36 health survey: Manual and interpretation guide
TL;DR: TheSF-36 is a generic health status measure which has gained popularity as a measure of outcome in a wide variety of patient groups and social and the contribution of baseline health, sociodemographic and work-related factors to the SF-36 Health Survey: manual and interpretation guide is tested.
Journal ArticleDOI
Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health.
Richard P. Allen,Daniel L. Picchietti,Wayne A. Hening,Claudia Trenkwalder,Arthur S. Walters,Jacques Montplaisi +5 more
TL;DR: Modification of the criteria for the diagnosis of restless legs syndrome is modified to better reflect that increased body of knowledge, as well as to clarify slight confusion with the wording of the original criteria.
Journal ArticleDOI
Toward a better definition of the restless legs syndrome
Arthur S. Walters,Michael S. Aldrich,Richard P. Allen,Sonia Ancoli-Israel,David W. Buchholz,Sudhansu Chokroverty,Giorgio Coccagna,Christopher J. Earley,Bruce L. Ehrenberg,T. G. Feest,Wayne A. Hening,Neil B. Kavey,Gilles Lavigne,Joseph F. Lipinski,Elio Lugaresi,Pasquale Montagna,Jacques Montplaisir,Sarah S. Mosko,Wolfgang H. Oertel,Daniel L. Picchietti,Thomas Pollmächer,Renata Shafor,Robert C. Smith,Wenche Telstad,C. Trenkwalder,C. Trenkwalder,Christian von Scheele,J. Catesby Ware,Marco Zucconi +28 more
TL;DR: A large International Restless Legs Syndrome (RLS) Study Group has been formed as discussed by the authors, which has taken upon itself the role of definig the clinical features of the RLS, including sleep disturbance, periodic limb movements in sleep and similar involuntary movements while awake, a normal neurological examination in the idiopathic from, a tendency for the symptoms to be worse in middle to older age, and a family history suggestive of an autosomal dominant mode of inheritance.
Journal ArticleDOI
Sex and the risk of restless legs syndrome in the general population.
TL;DR: Restless legs syndrome is a common disease in the general population, affecting women more often than men, and is associated with reduced quality of life in cross-sectional analysis.
Journal ArticleDOI
Restless legs syndrome and sleep bruxism : prevalence and association among Canadians
TL;DR: The data suggest that both sleep movement disorders can be concomitant and that socio-geographic and age characteristics influence the prevalence of reports.
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