Journal ArticleDOI
Saponins in the genus Panax L. (Araliaceae): A systematic review of their chemical diversity
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TLDR
This comprehensive review describes the advances in the phytochemistry of the genus Panax for the period 1963-2012, based on the 134 cited references, with special attention being paid to the structural features of the six different subtypes.About:
This article is published in Phytochemistry.The article was published on 2014-10-01. It has received 232 citations till now. The article focuses on the topics: Panax notoginseng & Dammarane.read more
Citations
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Journal ArticleDOI
Pharmacological potential of ginseng and its major component ginsenosides
Zubair Ahmed Ratan,Mohammad Faisal Haidere,Yo Han Hong,Sang Hee Park,Jeong-Oog Lee,Jongsung Lee,Jae Youl Cho +6 more
TL;DR: Ginseng could be a valuable resource for future drug development; however, further higher quality evidence is required as it may have drug interactions although the available evidence suggests it is a relatively safe product.
Journal ArticleDOI
Approaches to establish Q-markers for the quality standards of traditional Chinese medicines.
TL;DR: This review delineates the background, definition, and properties of Q-marker, and the associated technologies applied for its establishment, and strategies and approaches for establishing Q- marker-based TCM quality control system.
Book ChapterDOI
Saponin-Based, Biological-Active Surfactants from Plants
Dorota Kregiel,Joanna Berlowska,Izabela Witońska,HubertAntolak,Charalampos Proestos,Mirko Babić,Ljiljana Babić,Bolin Zhang +7 more
TL;DR: This chapter has been prepared by participants of the Marie Sklodowska‐Curie Action—Research and Innovation Staff Exchange (RISE) in the frame‐ work of the proposal ‘ECOSAPONIN.’
Journal ArticleDOI
Analytical methods and biological activities of Panax notoginseng saponins: Recent trends
TL;DR: The chromatographic technique remains the most extensively used approach for the identification or quantitation of PNSs, coupled with different detectors, among which the difference mainly lies in their sensitivity and specificity for analyzing various compounds.
Journal ArticleDOI
A green protocol for efficient discovery of novel natural compounds: characterization of new ginsenosides from the stems and leaves of Panax ginseng as a case study.
Shi Qiu,Wen-zhi Yang,Xiaojian Shi,Changliang Yao,Min Yang,Xuan Liu,Baohong Jiang,Wanying Wu,Dean Guo +8 more
TL;DR: The established 2D LC/LTQ-Orbitrap-MS/NMR approach outperforms the conventional approaches in respect of significantly improved efficiency, much less use of drug materials and organic solvent.
References
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Journal ArticleDOI
Saponins, classification and occurrence in the plant kingdom
TL;DR: The oleanane skeleton was the most common skeleton and is present in most orders of the plant kingdom, and the relationship between the type of skeleton and the plant origin was investigated.
Journal ArticleDOI
Pharmacology of ginsenosides: a literature review.
Kar Wah Leung,Alice S.T. Wong +1 more
TL;DR: The structure, systemic transformation and bioavailability of ginsenosides are reviewed before illustration on how these molecules exert their functions via interactions with steroidal receptors are illustrated.
Journal ArticleDOI
Steaming of Ginseng at High Temperature Enhances Biological Activity
Wang Yu Kim,Jong Moon Kim,Sang Beom Han,Seung Ki Lee,Nak Doo Kim,Man Ki Park,Chong Kook Kim,Jeong Hill Park +7 more
TL;DR: The ginseng steamed at 120 degrees C was more potent in its ability to induce endothelium-dependent relaxation and remarkably increased the radical-scavenging activity.
Journal ArticleDOI
Pharmacological activity of sanchi ginseng (Panax notoginseng).
TL;DR: The pharmacological activity and constituents of the sanchi ginseng Panax notoginseng have been reviewed and Protective actions against cerebral ischaemia, beneficial effects on the cardiovascular system, and haemostatic, antioxidant, hypolipidaemic, hepatoprotective, renoprotsective and estrogen‐like activities have been described.
Journal ArticleDOI
Antioxidant and anti-tumor promoting activities of the methanol extract of heat-processed ginseng.
Young-Sam Keum,Kwang Kyun Park,Jong-Min Lee,Kyung-Soo Chun,Jeong Hill Park,Seung Ki Lee,Hoonjeong Kwon,Young-Joon Surh +7 more
TL;DR: The methanol extract of heat-processed neoginseng (designated as 'NGMe') attenuated lipid peroxidation in rat brain homogenates induced by ferric ion or ferric ions plus ascorbic acid and inhibited TPA-induced production of tumor necrosis factor- in mouse skin was inhibited by NGMe pretreatment.