Journal ArticleDOI
Scales to measure dimensions of hallucinations and delusions: the psychotic symptom rating scales (PSYRATS).
TLDR
It is concluded that the PSYRATS are useful assessment instruments and can complement existing measures and have excellent inter-rater reliability.Abstract:
BACKGROUND: Scales to measure the severity of different dimensions of auditory hallucinations and delusions are few. Biochemical and psychological treatments target dimensions of symptoms and valid and reliable measures are necessary to measure these. METHOD: The inter-rater reliability and validity of the Psychotic Symptom Rating Scales (PSYRATS: auditory hallucination subscale and delusions subscale), which measure several dimensions of auditory hallucinations and delusions were examined in this study. RESULTS: The two scales were found to have excellent inter-rater reliability. Their validity as compared with the KGV scale (Krawiecka et al. 1977) was explored. CONCLUSIONS: It is concluded that the PSYRATS are useful assessment instruments and can complement existing measures.read more
Citations
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Journal ArticleDOI
Befriending patients with medication-resistant schizophrenia: can psychotic symptoms predict treatment response?
N. Samarasekera,David Kingdon,Ronald Siddle,M. O'Carroll,Jan Scott,Tom Sensky,Thomas R. E. Barnes,Douglas Turkington +7 more
TL;DR: Baseline psychotic symptoms strongly predicted outcome and hallucinations predicted a poor outcome, consistent with previous research, which may help to determine which patients would benefit from supportive interventions.
Journal ArticleDOI
Gene polymorphisms and response to transcranial direct current stimulation for auditory verbal hallucinations in schizophrenia.
Harleen Chhabra,Venkataram Shivakumar,Manjula Subbanna,Sunil V. Kalmady,Anushree Bose,Sri Mahavir Agarwal,Vanteemar S. Sreeraj,Damodharan Dinakaran,Janardhanan C. Narayanaswamy,Monojit Debnath,Ganesan Venkatasubramanian +10 more
TL;DR: ComT-GG and NRG1-AA genotypes aid the tDCS-induced improvement in AVHs in schizophrenia patients and need replication and further systematic research to understand the neuroplastic gene determinants that modulate the effect of tDCS.
Journal ArticleDOI
Neurocognitive capabilities modulate the integration of evidence in schizophrenia.
Sarah Eifler,Franziska Rausch,Frederike Schirmbeck,Ruth Veckenstedt,Susanne Englisch,Andreas Meyer-Lindenberg,Peter Kirsch,Mathias Zink +7 more
TL;DR: Patients with schizophrenia show a bias in the integration of confirmatory but not disconfirmatory evidence and a liberal acceptance of belief formation, and neurocognitive functioning emerged as a modulatory factor that should be considered in further research.
Journal ArticleDOI
C4A mRNA expression in PBMCs predicts the presence and severity of delusions in schizophrenia and bipolar disorder with psychosis
TL;DR: It is shown that C4A mRNA expression alone is positively associated with psychotic symptomatology, specifically the presence and severity of delusions, which is noteworthy given recent findings that demonstrate a critical role for complement proteins in synaptic pruning.
Journal ArticleDOI
Abnormal synchrony and effective connectivity in patients with schizophrenia and auditory hallucinations
María de la Iglesia-Vayá,Maria Jose Escartí,José Molina-Mateo,Luis Martí-Bonmatí,Marien Gadea,Francisco X. Castellanos,Francisco X. Castellanos,Eduardo J. Aguilar García-Iturrospe,Montserrat Robles,Bharat B. Biswal,Julio Sanjuán +10 more
TL;DR: Functional connectivity data indicate that an anomalous process of neural connectivity exists when patients with AH process emotional auditory stimuli, and a central role is suggested for the cerebellum in processing emotional stimuli in patients with persistent AH.
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