Journal ArticleDOI
Separation of viable schizont-infected red cells of Plasmodium falciparum from human blood.
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This article is published in Annals of Tropical Medicine and Parasitology.The article was published on 1978-02-01. It has received 351 citations till now. The article focuses on the topics: Plasmodium falciparum.read more
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Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes.
Joseph D. Smith,Chetan E. Chitnis,Alistar G. Craig,David J. Roberts,Diana E. Hudson-Taylor,David S. Peterson,Robert Pinches,Chris I. Newbold,Louis H. Miller +8 more
TL;DR: It is shown that expression of variant antigenic determinants is correlated with expression of individual members of a large, multigene family named var, which is consistent with the involvement of var genes in antigenic variation and binding to endothelium.
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Refractive index maps and membrane dynamics of human red blood cells parasitized by Plasmodium falciparum.
YongKeun Park,Monica Diez-Silva,Gabriel Popescu,George Lykotrafitis,Wonshik Choi,Michael S. Feld,Subra Suresh +6 more
TL;DR: Two intrinsic indicators: the refractive index and membrane fluctuations in P. falciparum-invaded human RBCs are investigated and offer potential avenues for identifying, through cell membrane dynamics, pathological states that cause or accompany human diseases.
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Membrane Transport in the Malaria-Infected Erythrocyte
TL;DR: This review focuses on the transport properties of the different membranes of the malaria-infected erythrocyte, as well as on the role played by the various membrane transport systems in the uptake of solutes from the extracellular medium, the disposal of metabolic wastes, and the origin and maintenance of electrochemical ion gradients.
Journal ArticleDOI
Cellular mechanism for the protective effect of haemoglobin S against P. falciparum malaria.
TL;DR: This work has compared the rates of invasion and growth of P. falciparum in normal red cells and in those of individuals with the sickling disorders, in both aerobic conditions and conditions of reduced oxygen tension, and suggests a possible mechanism for the protection of sickle-cell heterozygotes against P. Falconerum malaria.
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Plasmodium falciparum domain mediating adhesion to chondroitin sulfate A: A receptor for human placental infection
Pierre Buffet,Benoit Gamain,Christine Scheidig,Dror I. Baruch,Joseph D. Smith,Rosaura Hernández-Rivas,Bruno Pouvelle,Shinya Oishi,Nobutaka Fujii,Thierry Fusai,Daniel Parzy,Louis H. Miller,Jürg Gysin,Artur Scherf +13 more
TL;DR: Because protective antibodies present after pregnancy block binding to CSA of parasites from different parts of the world, DBL-3, although variant, may induce cross-reactive immunity that will protect pregnant women and their fetuses.