Journal ArticleDOI
Skin cancer in solid organ transplant recipients: Advances in therapy and management: Part II. Management of skin cancer in solid organ transplant recipients
Fiona O. Zwald,Marc D. Brown +1 more
TLDR
In this paper, a continuing medical education review offers an approach to the management of skin cancer in solid organ transplant recipients, including topical therapies, photodynamic therapy, systemic retinoids, and capecitabine.Abstract:
The management of skin cancer in solid organ transplant recipients is a challenge to both the dermatologist and transplant physician. Part II of this continuing medical education review offers an approach to the management of this increasing problem. The importance of specialty dermatology clinics providing access to transplant patients, frequent skin cancer screening, patient education, and multidisciplinary care is discussed. The management of low risk squamous cell carcinoma with topical therapies, photodynamic therapy, systemic retinoids, and capecitabine is reviewed. Revision of immunosuppression in the management of high-risk patients is discussed in association with the potential role of sentinel lymph node biopsy for aggressive disease. Finally, management of in-transit and metastatic squamous cell carcinoma is reviewed, with a discussion of the role of more recent innovative therapies, including epidermal growth factor receptor inhibitors in advanced squamous cell carcinoma in solid organ transplant recipients.read more
Citations
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Practice guidelines for the diagnosis and management of aspergillosis: 2016 update by the infectious diseases society of America
Thomas F. Patterson,George Richard Thompson,David W. Denning,Jay A. Fishman,Susan Hadley,Raoul Herbrecht,Dimitrios P. Kontoyiannis,Kieren A. Marr,Vicki A. Morrison,M. Hong Nguyen,Brahm H. Segal,William J. Steinbach,David A. Stevens,Thomas J. Walsh,John R. Wingard,Jo Anne H. Young,John E. Bennett +16 more
TL;DR: IDSA considers adherence to these guidelines to be voluntary, with the ultimate determination regarding their application to be made by the physician in the light of each patient's individual circumstances.
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Cutaneous squamous cell carcinoma: Incidence, risk factors, diagnosis, and staging
TL;DR: The incidence, recurrence rates, mortality rates, and risk factors associated with cSCC are discussed and the staging systems used to stratify patients into high- and low-risk groups are reviewed.
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Diagnosis and treatment of invasive squamous cell carcinoma of the skin: European consensus-based interdisciplinary guideline
Alexander J. Stratigos,Claus Garbe,Céleste Lebbé,Josep Malvehy,Véronique Del Marmol,Hubert Pehamberger,Ketty Peris,Juergen C. Becker,Iris Zalaudek,Philippe Saiag,Mark R. Middleton,Lars Bastholt,Alessandro Testori,Jean-Jacques Grob +13 more
TL;DR: The EDF-EADO-EORTC consensus group recommends a standardised minimal margin of 5 mm even for low-risk tumours and a lymph node ultrasound is highly recommended, particularly in tumours with high-risk characteristics.
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Interventions for non-metastatic squamous cell carcinoma of the skin: systematic review and pooled analysis of observational studies
Louise Lansbury,Fiona Bath-Hextall,Fiona Bath-Hextall,William Perkins,Wendy Stanton,Jo Leonardi-Bee +5 more
TL;DR: Assessment of the effects of treatments for non-metastatic invasive squamous cell carcinoma of the skin using evidence from observational studies to improve the evidence base for this common cancer and to optimise clinical management found many observational studies have looked at different treatment modalities for SCC.
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Cutaneous Squamous Cell Carcinoma: A Review of High-Risk and Metastatic Disease
TL;DR: Treatment of metastatic cSCC is difficult and depends on the location involved and extent of metastasis, and the supporting evidence is inconsistent and a curative chemotherapeutic approach is still lacking.
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