Smell and taste dysfunction in patients with COVID-19.
Michael S Xydakis,Puya Dehgani-Mobaraki,Eric H. Holbrook,Urban W. Geisthoff,Christian Bauer,Charlotte Hautefort,Philippe Herman,Geoffrey T. Manley,Dina M Lyon,Claire Hopkins +9 more
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This article is published in Lancet Infectious Diseases.The article was published on 2020-04-15 and is currently open access. It has received 282 citations till now. The article focuses on the topics: Dysgeusia & Taste.read more
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Journal ArticleDOI
The Prevalence of Olfactory and Gustatory Dysfunction in COVID-19 Patients: A Systematic Review and Meta-analysis.
TL;DR: Olfactory and gustatory dysfunction are common symptoms in patients with COVID-19 and may represent early symptoms in the clinical course of infection and increased awareness of this fact may encourage earlier diagnosis and treatment, as well as heighten vigilance for viral transmission.
Journal ArticleDOI
Neurobiology of COVID-19.
TL;DR: This article reviews the reports that address neurological manifestations in patients with COVID-19, who may present with acute neurological symptoms, even without typical respiratory symptoms such as fever, cough, or shortness of breath, and proposes a basic "NeuroCovid" classification scheme that integrates these concepts.
Journal ArticleDOI
COVID-19: Specific and non-specific clinical manifestations and symptoms: The current state of knowledge
Jacek Baj,Hanna Karakuła-Juchnowicz,Grzegorz Teresiński,Grzegorz Buszewicz,Marzanna Ciesielka,Elżbieta Sitarz,Alicja Forma,Kaja Karakuła,Wojciech Flieger,Piero Portincasa,Ryszard Maciejewski +10 more
TL;DR: The aim of this paper is to review and summarize all of the findings regarding clinical manifestations of COVID-19 patients, which include respiratory, neurological, olfactory and gustatory, gastrointestinal, ophthalmic, dermatological, cardiac, and rheumatologic manifestations, as well as specific symptoms in pediatric patients.
Journal ArticleDOI
COVID-19-related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters.
Guilherme D. Melo,Françoise Lazarini,Sylvain Levallois,Sylvain Levallois,Charlotte Hautefort,Vincent Michel,Vincent Michel,Florence Larrous,Benjamin Verillaud,Caroline Aparicio,Sebastien Wagner,Gilles Gheusi,Gilles Gheusi,Lauriane Kergoat,Etienne Kornobis,Flora Donati,Flora Donati,Thomas Cokelaer,Remi Hervochon,Yoann Madec,Emmanuel Roze,Dominique Salmon,Hervé Bourhy,Marc Lecuit,Marc Lecuit,Marc Lecuit,Pierre-Marie Lledo +26 more
TL;DR: In this article, a virologic, molecular, and cellular study of the olfactory neuroepithelium of seven patients with COVID-19 presenting with acute loss of smell was conducted.
Journal ArticleDOI
Higher infectivity of the SARS-CoV-2 new variants is associated with K417N/T, E484K, and N501Y mutants: An insight from structural data.
Abbas Khan,Tauqir Zia,Muhammad Suleman,Taimoor Khan,Syed Shujait Ali,Aamir Ali Abbasi,Anwar Mohammad,Dong-Qing Wei +7 more
TL;DR: In this article, a structural and biophysical analysis of the Spike glycoprotein of SARS-CoV-2 new variants has been carried out to understand the binding and structural dynamics of the new mutations in the RBD domain of Spike protein.
References
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Journal ArticleDOI
The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients
TL;DR: It remains to make clear whether the potential invasion of SARS‐CoV2 is partially responsible for the acute respiratory failure of patients with COVID‐19, which emerged in December 2019 in Wuhan, China and rapidly spreads around the world.
Journal ArticleDOI
Self-reported Olfactory and Taste Disorders in Patients With Severe Acute Respiratory Coronavirus 2 Infection: A Cross-sectional Study.
Andrea Giacomelli,Laura Pezzati,Federico Conti,Dario Bernacchia,Matteo Siano,Letizia Oreni,Stefano Rusconi,Cristina Gervasoni,Anna Lisa Ridolfo,Giuliano Rizzardini,Spinello Antinori,Massimo Galli +11 more
TL;DR: Survey shows that OTDs are fairly frequent in patients with SARS-CoV-2 infection and may precede the onset of full-blown clinical disease, which could explain the underlying pathogenetic mechanism of taste and olfactory disorders in SARS.
Posted ContentDOI
Neurological Manifestations of Hospitalized Patients with COVID-19 in Wuhan, China: a retrospective case series study
Ling Mao,Mengdie Wang,Shanghai Chen,Quan-Wei He,Jiang Chang,Candong Hong,Yifan Zhou,David Z. Wang,Yanan Li,Huijuan Jin,Bo Hu +10 more
TL;DR: In this paper, the neurological manifestations of patients with coronavirus disease 2019 (COVID-19) were studied in three categories: central nervous system (CNS) symptoms or diseases (headache, dizziness, impaired consciousness, ataxia, acute cerebrovascular disease, and epilepsy), peripheral nervous system symptoms (hypogeusia, hyposmia, hypopsia, and neuralgia), and skeletal muscular symptoms.
Journal ArticleDOI
Identification of Viruses in Patients With Postviral Olfactory Dysfunction
Motohiko Suzuki,Koichi Saito,Wei-Ping Min,Costin Vladau,Kazunori Toida,Hirotaka Itoh,Shingo Murakami +6 more
TL;DR: Cusative viruses of postviral olfactory dysfunction (PVOD) have not yet been identified and the aim of this study was to investigate causative viruses in patients with PVOD.
Book ChapterDOI
Neuroinvasive and neurotropic human respiratory coronaviruses: potential neurovirulent agents in humans.
TL;DR: It has been suggested that these recognized human respiratory pathogens could be associated with the triggering or the exacerbation of neurological diseases for which the etiology remains unknown or poorly understood.
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