Staphylococcus aureus in Dermatology Outpatients with Special Emphasis on Community-Associated Methicillin-Resistant Strains
Uta Jappe,D Heuck,Birgit Strommenger,Constanze Wendt,Guido Werner,Doris Altmann,Wolfgang Witte +6 more
TLDR
Investigation of dermatology outpatients with inflammatory skin diseases, leg ulcers, and skin infections for Panton-Valentine leukocidin (PVL)-positive S. aureus finds far-1-coded FUS resistance represents a typical marker for the widespread CA-MRSA ST080 in Europe, especially in Germany.About:
This article is published in Journal of Investigative Dermatology.The article was published on 2008-11-01 and is currently open access. It has received 64 citations till now. The article focuses on the topics: Staphylococcus aureus & Skin infection.read more
Citations
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Harmonization of pulsed-field gel electrophoresis protocols for epidemiological typing of strains of methicillin-resistant Staphylococcus aureus: a single approach developed by consensus in 10 European laboratories and its applicatio
Murchan S,Kaufmann M E,Deplano A,Ryck de R,Struelens M,Zinn C E,Fussig,Salmenlinna S,Vuopio-Varkila J,El Solh N,Cuny C,Witte W,Tassios P T,Legakis N,Leeuwen van W,Belkum van A,Vindel A,Laconcha I,Garaizar J,Haeggman S,Olsson-Liljequist B,Ransjo U,Coombes G,Cookson B +23 more
TL;DR: In this article, the authors compared different European pulsed-fieldgel electrophoresis (PFGE) protocols for MRSA and of the various national MRSA clones themselves.
Journal ArticleDOI
Methicillin-Resistant Staphylococcus aureus (MRSA): Burden of disease and control challenges in Europe
Robin Köck,Karsten Becker,Barry Cookson,J.E.W.C. van Gemert-Pijnen,Stéphan Juergen Harbarth,Jan Kluytmans,Martin Mielke,Georg Peters,Robert Skov,Marc Struelens,Marc Struelens,Evelina Tacconelli,A Navarro Torné,Wolfgang Witte,Alexander W. Friedrich +14 more
TL;DR: The current burden of MRSA infections in healthcare and community settings across Europe is described and the main threats caused by recent changes in the epidemiology of MR SA are outlined, aimed at identifying unmet needs of surveillance, prevention and control ofMRSA in Europe.
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Mobile genetic elements of Staphylococcus aureus
Natalia Malachowa,Frank R. DeLeo +1 more
TL;DR: Understanding of S. aureus MGEs and the molecules they encode has played an important role toward these ends and has provided detailed insight into the evolution of antimicrobial resistance mechanisms and virulence.
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The role of the Panton-Valentine leucocidin toxin in staphylococcal disease: a systematic review and meta-analysis
TL;DR: PVL genes are consistently associated with skin and soft-tissue infections and are comparatively rare in invasive disease, challenging the view that PVL mainly causes invasive disease with poor prognosis.
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High genetic diversity among community-associated Staphylococcus aureus in Europe: results from a multicenter study.
Joana Rolo,Maria Miragaia,Agata Turlej-Rogacka,Joanna Empel,Ons Bouchami,Nuno A. Faria,Ana Tavares,Waleria Hryniewicz,Ad C. Fluit,Hermínia de Lencastre,Hermínia de Lencastre +10 more
TL;DR: The results imply that CA-MRSA origin, epidemiology and population structure in Europe is very dissimilar from that of USA.
References
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Staphylococcus aureus infections.
TL;DR: In an elegant series of clinical observations and laboratory studies published in 1880 and 1882, Ogston described staphylococcal disease and its role in sepsis and abscess formation.
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CDC definitions for nosocomial infections, 1988
TL;DR: The Centers for Disease Control (CDC) developed a new set of definitions for surveillance of nosocomial infections as mentioned in this paper, which combine specific clinical findings with results of laboratory and other tests that include recent advances in diagnostic technology.
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Involvement of Panton-Valentine Leukocidin—Producing Staphylococcus aureus in Primary Skin Infections and Pneumonia
Gerard Lina,Yves Piémont,Florence Godail-Gamot,Michèle Bes,Marie Odile Peter,Valérie Gauduchon,François Vandenesch,Jerome Etienne +7 more
TL;DR: Panton-Valentine leukocidin genes were detected in 93% of strains associated with furunculosis and in 85% of those associated with severe necrotic hemorrhagic pneumonia (all community-acquired), and it appears that PVL is mainly associated with nec rotic lesions involving the skin or mucosa.
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Comparison of community- and health care-associated methicillin-resistant Staphylococcus aureus infection.
Timothy S. Naimi,Kathleen H. LeDell,Kathryn Como-Sabetti,Stephanie M. Borchardt,David Boxrud,Jerome Etienne,Susan K. Johnson,François Vandenesch,Scott K. Fridkin,Carol O'Boyle,Richard Danila,Ruth Lynfield +11 more
TL;DR: It is suggested that most community-associated MRSA strains did not originate in health care settings, and that their microbiological features may have contributed to their emergence in the community.