Journal ArticleDOI
Stem cell recruitment and angiogenesis of neuropeptide substance P coupled with self-assembling peptide nanofiber in a mouse hind limb ischemia model.
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TLDR
It was demonstrated that bioactive peptides are one of the most powerful tools for the treatment of ischemia, through their recruitment of autologous MSCs and promotion of angiogenesis without cells transplantation.About:
This article is published in Biomaterials.The article was published on 2013-02-01. It has received 88 citations till now. The article focuses on the topics: Transplantation & Mesenchymal stem cell.read more
Citations
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Tissue repair and regeneration with endogenous stem cells
TL;DR: Important differences in the self-regeneration abilities of non-mammalian vertebrates and mammals, including humans, are discussed, and regeneration approaches in combination with natural and synthetic biomaterials are investigated.
Journal ArticleDOI
Strategies to develop endogenous stem cell-recruiting bioactive materials for tissue repair and regeneration.
Settimio Pacelli,Sayantani Basu,Jonathan Whitlow,Aparna R. Chakravarti,Francisca M. Acosta,Arushi Varshney,Saman Modaresi,Cory Berkland,Arghya Paul +8 more
TL;DR: This review introduces the concept of endogenous stem cell recruitment, and provides a comprehensive overview of the strategies available to achieve effective cardiovascular and bone tissue regeneration.
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Concise Review: Injectable Biomaterials for the Treatment of Myocardial Infarction and Peripheral Artery Disease: Translational Challenges and Progress
TL;DR: The overall goal is to highlight the major challenges facing translation of these therapies to the clinic with the purpose of increasing awareness of the barriers for translating novel biomaterial therapies for MI and PAD and facilitating more rapid translation of new biomaterial technologies.
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Insight on stem cell preconditioning and instructive biomaterials to enhance cell adhesion, retention, and engraftment for tissue repair.
TL;DR: This work describes how preconditioning of cells or cell manipulations strategies can enhance stem cell survival and engraftment after transplantation and discusses how biomaterials can enhance the function of stem cells for effective tissue regeneration.
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A brief review: adipose-derived stem cells and their therapeutic potential in cardiovascular diseases
TL;DR: The differentiation and paracrine functions of ADSCs, the strategies promoting their therapeutic efficacy, and their clinical usage are discussed.
References
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Journal ArticleDOI
Bone marrow cells regenerate infarcted myocardium
Donald Orlic,Jan Kajstura,Stefano Chimenti,Igor Jakoniuk,Stacie M. Anderson,Baosheng Li,James Pickel,Ronald D.G. McKay,Bernardo Nadal-Ginard,David M. Bodine,Annarosa Leri,Piero Anversa +11 more
TL;DR: It is indicated that locally delivered bone marrow cells can generate de novo myocardium, ameliorating the outcome of coronary artery disease.
Journal ArticleDOI
Heart Disease and Stroke Statistics—2011 Update A Report From the American Heart Association
Véronique L. Roger,Alan S. Go,Donald M. Lloyd-Jones,Robert J. Adams,Jarett D. Berry,Todd M. Brown,Mercedes R. Carnethon,Shifan Dai,Giovanni de Simone,Earl S. Ford,Caroline S. Fox,Heather J. Fullerton,Cathleen Gillespie,Kurt J. Greenlund,Susan M. Hailpern,John A. Heit,P. Michael Ho,Virginia J. Howard,Brett M. Kissela,Steven J. Kittner,Daniel T. Lackland,Judith H. Lichtman,Lynda D. Lisabeth,Diane M. Makuc,Gregory M. Marcus,Ariane Marelli,David B. Matchar,Mary M. McDermott,James B. Meigs,Claudia S. Moy,Dariush Mozaffarian,Michael E. Mussolino,Graham Nichol,Nina P. Paynter,Wayne D. Rosamond,Paul D. Sorlie,Randall S. Stafford,Tanya N. Turan,Melanie B. Turner,Nathan D. Wong,Judith Wylie-Rosett +40 more
TL;DR: Dariush Mozaffarian, Michael E. Mussolino, Graham Nichol, Nina P. Paynter, Wayne D. Sorlie, Randall S. Stafford, Tanya N. Turan, Melanie B. Turner, Nathan D. Turner.
Journal ArticleDOI
A perivascular origin for mesenchymal stem cells in multiple human organs
Mihaela Crisan,Solomon Yap,Louis Casteilla,Louis Casteilla,Chien Wen Chen,Mirko Corselli,Tea Soon Park,Gabriella Andriolo,Bin Sun,Bo Zheng,Li Zhang,Cyrille Norotte,Pang-ning Teng,Jeremy Traas,Rebecca C. Schugar,Bridget M. Deasy,Stephen F. Badylak,Hans-Jörg Bühring,Jean-Paul Giacobino,Lorenza Lazzari,Johnny Huard,Bruno Péault +21 more
TL;DR: Blood vessel walls harbor a reserve of progenitor cells that may be integral to the origin of the elusive MSCs and other related adult stem cells.
Journal ArticleDOI
Fabrication of novel biomaterials through molecular self-assembly.
TL;DR: Two complementary strategies can be used in the fabrication of molecular biomaterials as discussed by the authors : chemical complementarity and structural compatibility, both of which confer the weak and noncovalent interactions that bind building blocks together during self-assembly.
Journal ArticleDOI
Mesenchymal stem cells enhance wound healing through differentiation and angiogenesis.
TL;DR: The data suggest that bone marrow‐derived mesenchymal stem cells promote wound healing through differentiation and release of proangiogenic factors.