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Structure and function of large-scale brain systems.

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TLDR
This article introduces the functional neuroanatomy of large-scale brain systems, a system of brain function completely changes understanding of how cognition and behavior are organized within the brain, replacing the traditional lesion model.
Abstract
This article introduces the functional neuroanatomy of large-scale brain systems. Both the structure and functions of these brain networks are presented. All human behavior is the result of interactions within and between these brain systems. This system of brain function completely changes our understanding of how cognition and behavior are organized within the brain, replacing the traditional lesion model. Understanding behavior within the context of brain network interactions has profound implications for modifying abstract constructs such as attention, learning, and memory. These constructs also must be understood within the framework of a paradigm shift, which emphasizes ongoing interactions within a dynamically changing environment.

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Citations
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Development of brain structural connectivity between ages 12 and 30: A 4-Tesla diffusion imaging study in 439 adolescents and adults

TL;DR: This large-scale analysis of the developing structural connectome offers a foundation to develop statistical criteria for aberrant brain connectivity as the human brain matures.
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Lifespan anxiety is reflected in human amygdala cortical connectivity.

TL;DR: Data clearly indicated that both low‐level sensory networks and high‐level associative networks could contribute to detectable predictions of anxiety behaviors by their iFC profiles with the amygdala, which could lead to novel functional network models on neural correlates of human anxiety and provide targets for novel treatment strategies on anxiety disorders.
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Gender Differences Are Encoded Differently in the Structure and Function of the Human Brain Revealed by Multimodal MRI

TL;DR: The results suggest that gender differences are encoded in both brain structure and brain function, but in different manners, which may underlie the complex nature of gender differences in behavior.
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Uncovering cortical activations of discourse comprehension and their overlaps with common large-scale neural networks.

TL;DR: A meta-analysis of 78 task-based functional magnetic resonance imaging studies to reveal underlying brain activations and their overlap with large-scale neural networks in the brain during general discourse comprehension and its sub-processes finds that discourse comprehension relied most heavily on the default network, particularly on its dorsal medial subsystem.
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Transcranial magnetic stimulation of the medial prefrontal cortex for psychiatric disorders: a systematic review

TL;DR: Repetitive transcranial magnetic stimulation studies targeting the mPFC indicate that it may be a useful therapeutic resource in psychiatry due to its selective modulation of this area and connected regions, but the small number and low methodological quality of the studies indicate the need for further research.
References
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Journal ArticleDOI

The organization of the human cerebral cortex estimated by intrinsic functional connectivity

TL;DR: In this paper, the organization of networks in the human cerebrum was explored using resting-state functional connectivity MRI data from 1,000 subjects and a clustering approach was employed to identify and replicate networks of functionally coupled regions across the cerebral cortex.
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The Reorienting System of the Human Brain: From Environment to Theory of Mind

TL;DR: While originally conceptualized as a system for redirecting attention from one object to another, recent evidence suggests a more general role in switching between networks, which may explain recent evidence of its involvement in functions such as social cognition.

The of a Development

TL;DR: A good development plan is not a simple document as discussed by the authors. To be powerful, it has to be built around a development model grounded in real-world experience and have to be carefully crafted to fit the needs of the person being developed.
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Large-scale brain networks and psychopathology: a unifying triple network model

TL;DR: A triple network model of aberrant saliency mapping and cognitive dysfunction in psychopathology is proposed, emphasizing the surprising parallels that are beginning to emerge across psychiatric and neurological disorders.
Journal ArticleDOI

Characterization of the decision-making deficit of patients with ventromedial prefrontal cortex lesions.

TL;DR: Patients with VM lesions are insensitive to future consequences, positive or negative, and are primarily guided by immediate prospects, according to this study's designs of a variant of the original gambling task.
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