The importation and establishment of community transmission of SARS-CoV-2 during the first eight weeks of the South African COVID-19 epidemic
TLDR
The first eight weeks following COVID-19 importation were characterised by early predominance of imported cases and relatively low mortality and transmission rates, despite stringent lockdown measures, the second month following importation was characterisation by community transmission and increasing disease burden in more populous provinces.About:
This article is published in EClinicalMedicine.The article was published on 2021-09-01 and is currently open access. It has received 6 citations till now.read more
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Increased mortality among individuals hospitalised with COVID-19 during the second wave in South Africa
Waasila Jassat,Mudara C,Ozougwu L,Stefano Tempia,Stefano Tempia,Lucille Blumberg,M. A. Davies,Pillay Y,Carter T,Morewane R,Wolmarans M,von Gottberg A,von Gottberg A,Jinal N. Bhiman,Jinal N. Bhiman,Sibongile Walaza,Cheryl Cohen,Cheryl Cohen +17 more
TL;DR: In this paper, the authors compared the characteristics of hospitalised COVID-19 cases in wave 1 and wave 2, and risk factors for in-hospital mortality accounting for wave period using multivariable logistic regression.
Posted ContentDOI
SARS-CoV-2 incidence, transmission and reinfection in a rural and an urban setting: results of the PHIRST-C cohort study, South Africa, 2020-2021
Cheryl Cohen,Cheryl Cohen,Jackie Kleynhans,Jackie Kleynhans,Anne von Gottberg,Anne von Gottberg,Meredith McMorrow,Nicole Wolter,Nicole Wolter,Jinal N. Bhiman,Jinal N. Bhiman,Jocelyn Moyes,Jocelyn Moyes,Mignon du Plessis,Mignon du Plessis,Maimuna Carrim,Maimuna Carrim,Amelia Buys,Neil A. Martinson,Neil A. Martinson,Kathleen Kahn,Stephen Tollman,Limakatso Lebina,Floidy Wafawanaka,Jacques du Toit,Francesc Xavier Gómez-Olivé,Fatima S Dawood,Thulisa Mkhencele,Kaiyuan Sun,Cécile Viboud,Stefano Tempia,Stefano Tempia,Stefano Tempia +32 more
TL;DR: In this article, the authors conducted a prospective cohort study during July 2020-March 2021 in one rural and one urban community to estimate the burden and transmission of SARS-CoV-2 over the two waves.
Journal ArticleDOI
The Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Pandemic: Are Africa's Prevalence and Mortality Rates Relatively Low?
TL;DR: There are few studies on the epidemiology and pathogenesis of the disease in African contexts, and the overall costs and human life losses due to the pandemic in Africa will be determined by all factors and conditions interacting in complex ways.
Journal ArticleDOI
Changing Epidemiology of COVID-19 in Children and Adolescents Over Four Successive Epidemic Waves in South Africa, 2020–2022
Nicola Chiwandire,Ananya Uppal +1 more
TL;DR: In this paper , the authors analyzed national SARS-CoV-2 testing, case, and admissions data from March 2020 to February 2022 and estimated cumulative rates by age group for each endpoint.
Journal ArticleDOI
Impact of prior cryptococcal antigen screening on in-hospital mortality in cryptococcal meningitis or fungemia among HIV-seropositive individuals in South Africa: a cross-sectional observational study.
Olivier Paccoud,Liliwe Shuping,Rudzani C Mashau,Greg Greene,Vanessa Quan,Susan Meiring,Nelesh P. Govender +6 more
TL;DR: In this paper , the authors compared 14-day in-hospital case-fatality ratios of HIV-seropositive individuals with CD4 counts below 100 cells/μL and laboratory-confirmed CM/fungaemia from 2017-2021.
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Christian Karagiannidis,Carina Mostert,Corinna Hentschker,Thomas Voshaar,Jürgen Malzahn,Gerhard Schillinger,Jürgen Klauber,Uwe Janssens,Gernot Marx,Steffen Weber-Carstens,Stefan Kluge,Michael Pfeifer,Linus Grabenhenrich,Tobias Welte,Reinhard Busse +14 more
TL;DR: In the German health-care system, in which hospital capacities have not been overwhelmed by the COVID-19 pandemic, mortality has been high for patients receiving mechanical ventilation, particularly for patients aged 80 years or older and those requiring dialysis, and has been considerably lower for patients younger than 60 years.
Journal ArticleDOI
Risk factors for COVID-19 death in a population cohort study from the Western Cape Province, South Africa.
TL;DR: While the findings may over-estimate HIV- and tuberculosis-associated COVID-19 mortality risks due to residual confounding, both HIV and current tuberculosis were independently associated with increased COVID,19 mortality.
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