Journal ArticleDOI
The Pearson product‐moment correlation coefficient is better suited for identification of DNA fingerprint profiles than band matching algorithms
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TLDR
A database of DNA fingerprint profiles from permanently established human and animal cell lines was prepared with a computer program originally designed for numerical taxonomy of bacteria, and identified cell line DNA profiles both by the Pearson product‐moment correlation coefficient and by band matching.Abstract:
A database of DNA fingerprint profiles from permanently established human and animal cell lines was prepared with a computer program originally designed for numerical taxonomy of bacteria. Identifications of cell line DNA profiles were performed, both by the Pearson product-moment correlation coefficient and by band matching. Under the conditions used the Pearson product-moment correlation coefficient was consistently more reliable.read more
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Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease
S. J. Ott,Meike Musfeldt,D F Wenderoth,Jochen Hampe,O Brant,Ulrich R. Fölsch,Kenneth N. Timmis,Stefan Schreiber +7 more
TL;DR: Mucosal inflammation in inflammatory bowel disease is associated with loss of normal anaerobic bacteria, independent of NOD2/CARD15 status of patients.
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Mucosa-associated bacteria in the human gastrointestinal tract are uniformly distributed along the colon and differ from the community recovered from feces
Erwin G. Zoetendal,Terttu Vilpponen-Salmela,Kaouther Ben-Amor,Antoon D. L. Akkermans,Willem M. de Vos +4 more
TL;DR: The observed host-specific DGGE profiles of the mucosa-associated bacterial community in the colon support the hypothesis that host-related factors are involved in the determination of the GI tract microbial community.
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The Host Genotype Affects the Bacterial Community in the Human Gastrointestinal Tract
Erwin G. Zoetendal,Antoon D. L. Akkermans,Wilma M. Akkermans-van Vliet,J. Arjan G. M. de Visser,Willem M. de Vos +4 more
TL;DR: The data indicate that factors related to the host genotype have an important effect on determining the bacterial composition in the GI tract.
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Double blind, placebo controlled trial of two probiotic strains in interleukin 10 knockout mice and mechanistic link with cytokine balance
Jane McCarthy,Liam O'Mahony,L. O'Callaghan,B. Sheil,Elaine E. Vaughan,N.A. Fitzsimons,J. Fitzgibbon,Gerald C. O'Sullivan,Barry Kiely,John Kevin Collins,Fergus Shanahan +10 more
TL;DR: Both Lactobacillus salivarius and Bifidobacterium infantis 35624 significantly attenuate colitis in this murine model, associated with a reduced ability to produce Th1-type cytokines systemically and mucosally while levels of TGF-β are maintained.
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Biogeography and degree of endemicity of fluorescent Pseudomonas strains in soil.
Jae-Chang Cho,James M. Tiedje +1 more
TL;DR: Fluorescent Pseudomonas strains were isolated from 38 undisturbed pristine soil samples from 10 sites on four continents, suggesting that these heterotrophic soil bacteria are not globally mixed.
References
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Journal ArticleDOI
Hypervariable 'minisatellite' regions in human DNA.
TL;DR: A probe based on a tandem-repeat of the core sequence can detect many highly variable loci simultaneously and can provide an individual-specific DNA ‘fingerprint’ of general use in human genetic analysis.
Journal ArticleDOI
Individual-specific 'fingerprints' of human DNA.
TL;DR: It is shown that other variant (core)n probes can detect additional sets of hypervariable minisatellites to produce somatically stable DNA ‘fingerprints’ which are completely specific to an individual (or to his or her identical twin) and can be applied directly to problems of human identification, including parenthood testing.
Journal ArticleDOI
Variable number of tandem repeat (VNTR) markers for human gene mapping
Yusuke Nakamura,Mark Leppert,Peter O'Connell,Roger K. Wolff,Tom Holm,Melanie Culver,Cindy Martin,Esther Fujimoto,Mark Hoff,Erika Kumlin,Ray White +10 more
TL;DR: Ten oligomeric sequences derived from the tandem repeat regions of the myoglobin gene, the zeta-globin pseudogene, the insulin gene, and the X-gene region of hepatitis B virus were used to develop a series of single-copy probes that revealed new, highly polymorphic genetic loci whose allele sizes reflected variation in the number of tandem repeats.
Journal ArticleDOI
Forensic application of DNA 'fingerprints'.
TL;DR: It is shown that this technique can be used for forensic purposes; DNA of high relative molecular mass (Mr) can be isolated from 4-yr-old bloodstains and semen stains made on cotton cloth and digested to produce DNA fingerprints suitable for individual identification.
Journal ArticleDOI
Demographic study of a wild house sparrow population by DNA fingerprinting
TL;DR: It is reported that one of the human minisatellite clones is a suitable probe for sparrow DNA and that it reveals variation as extensive as that found in man, suggesting that analysis of minis Satellite DNA will be a powerful tool in the study of demographic population genetics.
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