Book ChapterDOI
Thiopyrans and Their Benzo Derivatives
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The article was published on 2020-01-01. It has received 1 citations till now. The article focuses on the topics: Ring (chemistry) & Section (typography).read more
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Regulated bioanalysis of conformers - A case study with ASP2151 in dog plasma and urine.
TL;DR: Bioanalytical methods for a potent helicase-primase inhibitor ASP2151 that has two conformers were developed and validated and successfully applied to a pharmacokinetic study in dogs, indicating discernable differences in hydrophobicity.
Journal ArticleDOI
Dorzolamide hydrochloride: an antiglaucoma agent.
TL;DR: A comparison is made with the dorzolamide bound in human carbonic anhydrase in the solid state, which is mediated by Cl− anions, resulting in indirect connectivity between the molecules.
Journal ArticleDOI
C ? C bond formation by radical cyclization: Facile syntheses of [6,6]pyranothiopyrans and [6,6]pyridothiopyrans
Journal ArticleDOI
Photooxidative degradation of QTX (a thioxanthone derivative)
Miguel G. Neumann,Carla C. Schmitt,Alessandra Lima Poli,José Carlos Netto-Ferreira,Josy Anteveli Osajima +4 more
TL;DR: In this paper, the photooxidative degradation of 2-hydroxy-3-(3,4-dimethyl-9-oxo-9H-thioxanthen-2-yloxy)-N, N,N-trimethyl-1-propanium chloride was investigated and photoproducts from QTX degradation in aqueous solution were characterized using HPLC/ESI-MS.
Journal ArticleDOI
Green and practical synthesis of functionalised 2 H -thiopyrans via one-pot multicomponent reactions of aryl isothiocyanates in water
TL;DR: In this paper, an efficient synthesis of thiopyran derivatives via one-pot reactions between methyl propiolates, aryl isothiocyanates and acetylacetone in water is described.