Book ChapterDOI
Thiopyrans and Their Benzo Derivatives
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The article was published on 2020-01-01. It has received 1 citations till now. The article focuses on the topics: Ring (chemistry) & Section (typography).read more
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MHz Unidirectional Rotation of Molecular Rotary Motors
TL;DR: Measurements at ambient temperature using transient absorption spectroscopy show that behavior of these motors is similar over the full temperature range investigated, thereby allowing a maximum rotation rate of 3 MHz at room temperature under suitable irradiation conditions.
Journal ArticleDOI
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Gustav Ahlin,Johan Karlsson,Jenny M. Pedersen,Lena Gustavsson,Rolf Larsson,Pär Matsson,Ulf Norinder,Christel A. S. Bergström,Per Artursson +8 more
TL;DR: High lipophilicity and a positive net charge were found to be the key physicochemical properties for OCT1 inhibition, whereas a high molecular dipole moment and many hydrogen bonds were negatively correlated to Oct1 inhibition.
Journal ArticleDOI
Enantioselective Intermolecular [2 + 2] Photocycloaddition Reactions of 2(1H)-Quinolones Induced by Visible Light Irradiation
TL;DR: Key to the success of the reactions is a two-point hydrogen bonding between quinolone and catalyst enabling efficient energy transfer and high enantioface differentiation.
Journal ArticleDOI
Lewis and Brønsted Acid Catalyzed Allylboration of Carbonyl Compounds: From Discovery to Mechanism and Applications
TL;DR: The recent development of catalytic enantioselective allylboration of carbonyl compounds has opened doors towards an ideal allylation methodology using stable and nontoxic allylic boronates as reagents as mentioned in this paper.
Journal ArticleDOI
Dopamine Targeting Drugs for the Treatment of Schizophrenia: Past, Present and Future.
TL;DR: Representative typical and atypical antipsychotic drugs and new investigational drug candidates will be systematically reviewed and compared by reviewing structure-activity relationships, pharmacokinetic properties, drug metabolism and safety, pharmacological properties, preclinical data in animal models, clinical outcomes and associated side effects.