BookDOI
Transmission Electron Microscopy
David B. Williams,C. Barry Carter +1 more
- pp 179-260
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The client would like to get a larger, approximately 3 cm in diameter, well fixed tissue sample, together with a detailed report of the clinical presentation, gross, and microscopic lesions, along with the submission of samples prepared in a similar manner by the client for processing.Abstract:
We wrote it to be read by, and taught to, senior undergraduates and starting graduate students, rather than studied in a research laboratory. We wrote it using the same style and sentence construction that we have used in countless classroom lectures, rather than how we have written our countless (and much-less read) formal scientificpapers. In this respect particularly, wehave been deliberate in notreferencing the sources of every experimental fact or theoretical concept (although we do include some hints and clues in the chapters). However, at the end of each chapter we have included groups of references that should lead you to the best sources in the literature and help you go into more depth as you become more confident about what you are looking for. We are great believers in the value of history as the basis for under- standing the present and so the history of the techniques and key historical references are threaded throughout the book. Just because a reference is dated in the previous century (or even the antepenultimate century) doesn’t mean it isn’t useful! Likewise, with the numerous figures drawn from across the fields of materials science and engineering and nanotechnology, we do not reference the source in each caption. But at the very end of the book each of our many generous colleagues whose work we have used is clearly acknowledged.read more
Citations
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Journal ArticleDOI
Effect of topoisomerase inhibitors and DNA-binding drugs on the cell proliferation and ultrastructure of Trypanosoma cruzi.
Aline Araujo Zuma,Danielle Pereira Cavalcanti,Marina C.P. Maia,Wanderley de Souza,Maria Cristina M. Motta +4 more
TL;DR: Results showed that the eukaryotic topoisomerase I inhibitors camptothecin and rebeccamycin were the most effective compounds in the arrest of T. cruzi proliferation and ultrastructure, and inhibitors of the same class may have different effects on trypanosomatid proliferation and Ultrastructure.
Journal ArticleDOI
Progress in the preparation of cross-sectional TEM specimens by ion-beam thinning
Adolf Strecker,Ute Bäder,Marion Kelsch,Ute Salzberger,Maria Sycha,Min Gao,Gunther Richter,Klaus van Benthem +7 more
TL;DR: In this article, the advantages of low-voltage ion polishing as a final step in the TEM specimen preparation by conventional ion-thinning is demonstrated for a case study for bulk SrTiO3 interfaces.
Journal ArticleDOI
Electron holography of thin amorphous carbon films: Measurement of the mean inner potential and a thickness-independent phase shift
TL;DR: It is suggested that a surface-related electrostatic potential is responsible for the thickness-independent contribution phi add, which is consistent with previous experimental data for amorphous carbon with a higher density.
Journal ArticleDOI
Evaluation of the microstructure of dry and hydrated perfluorosulfonic acid ionomers: microscopy and simulations
Chen Wang,Veena Krishnan,Dongsheng Wu,Rylan Bledsoe,Stephen J. Paddison,Gerd Duscher,Gerd Duscher +6 more
TL;DR: The morphology of dry and hydrated perfluorosulfonic acid (PFSA) ionomers at cryo and room temperature was examined using TEM/STEM with EELS capability as mentioned in this paper.
Journal ArticleDOI
Oleuropein reduces free fatty acid-induced lipogenesis via lowered extracellular signal-regulated kinase activation in hepatocytes
Wonhee Hur,Sung Woo Kim,Young-Ki Lee,Jung Eun Choi,Sung Woo Hong,Myeong Jun Song,Si Hyun Bae,Taesun Park,Soo-Jong Um,Seung Kew Yoon +9 more
TL;DR: Oleuropein decreased the number and size of lipid droplets in FFA-treated cells and reduced intracellular triglyceride accumulation, but it did not affect the expression of lipid Droplets-associated PAT family proteins, including adipose differentiation-related protein and TIP47.
References
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Journal ArticleDOI
Diffraction contrast from spherically symmetrical coherency strains
Michael F. Ashby,L. M. Brown +1 more
TL;DR: In this article, the properties of images formed by diffraction contrast in thin metal foils viewed by transmission electron microscopy are studied by means of the dynamical theory of diffraction, including absorption.
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XXXV. A tentative theory of light quanta
TL;DR: In this paper, it is shown mathematically that the Lorentz-Einstein transference of light quanta is a non-trivial process. But it is assumed that the light is essentially made up of light Quanta, all having the same extraordinarily small mass.
Journal ArticleDOI
Electron Microscope and Diffraction Study of Metal Crystal Textures by Means of Thin Sections
TL;DR: In this article, an electrolytic method for preparing thin metal sections for electron microscopy and diffraction is introduced and its application to the structure of cold-worked aluminum and an aluminum-copper alloy is demonstrated.