Journal ArticleDOI
Tumor-homing photosensitizer-conjugated glycol chitosan nanoparticles for synchronous photodynamic imaging and therapy based on cellular on/off system.
So Jin Lee,Heebeom Koo,Dong-Eun Lee,Solki Min,Solki Min,Seulki Lee,Xiaoyuan Chen,Yongseok Choi,James F. Leary,Kinam Park,Seo Young Jeong,Ick Chan Kwon,Kwangmeyung Kim,Kuiwon Choi +13 more
TLDR
Results proved that this tumor-homing cellular 'on/off' nanoparticle system of PpIX-GC-NPs has a great potential for synchronous photodynamic imaging and therapy in cancer treatment.About:
This article is published in Biomaterials.The article was published on 2011-06-01. It has received 158 citations till now. The article focuses on the topics: Photosensitizer & Photodynamic therapy.read more
Citations
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Journal ArticleDOI
Nanoparticles in photodynamic therapy.
TL;DR: This paper presents a meta-modelling study of the response of the immune system to chemotherapy and its applications in the context of central nervous system disorders.
Journal ArticleDOI
In vivo targeted delivery of nanoparticles for theranosis
Heebeom Koo,Myung Sook Huh,In Cheol Sun,Soon Hong Yuk,Kuiwon Choi,Kwangmeyung Kim,Ick Chan Kwon +6 more
TL;DR: This Account develops a glycol chitosan nanoparticle (CNP), which is suitable for angiogenic diseases, such as cancers, even without an additional targeting moiety, and develops hyaluronic acid nanoparticles that can bind efficiently to the CD44 antigen receptors abundant in many tumor cells.
Journal ArticleDOI
Polymeric Nanostructures for Imaging and Therapy.
TL;DR: High efficiency in diagnosis and treatment of diseases and improving patient quality of life and compliance can be achieved through understanding the molecular events associated with various diseases, and combining the advances in the design of therapeutic and diagnostic agents and nanomaterials, together with the innovative instruments utilized for monitoring these agents.
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Molecular Interactions in Organic Nanoparticles for Phototheranostic Applications
Kenneth K. Ng,Gang Zheng +1 more
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Nanomaterials formulations for photothermal and photodynamic therapy of cancer
Edakkattuparambil Sidharth Shibu,Morihiko Hamada,Norio Murase,Vasudevanpillai Biju,Vasudevanpillai Biju +4 more
TL;DR: In this article, different theranostic formulations of nanomaterials based on gold, silver, silica, semiconductor quantum dots, upconversion lanthanides, oxide magnets, polymers, liposomes, carbon nanotubes, graphene and carbon nanohorns, and their applications in photothermal and photodynamic therapy of cancer were reviewed.
References
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Photodynamic therapy for cancer
TL;DR: PDT is being tested in the clinic for use in oncology — to treat cancers of the head and neck, brain, lung, pancreas, intraperitoneal cavity, breast, prostate and skin.
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Drug Delivery Systems: Entering the Mainstream
TL;DR: There is considerable interest in exploiting the advantages of DDS for in vivo delivery of new drugs derived from proteomics or genomics research and for their use in ligand-targeted therapeutics.
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Nanoparticles as vehicles for delivery of photodynamic therapy agents
Denise Bechet,Pierre Couleaud,Céline Frochot,Marie-Laure Viriot,François Guillemin,Muriel Barberi-Heyob +5 more
TL;DR: This review describes and compares the different individual types of nanoparticles that are currently in use for PDT applications and describes the nanoparticles in terms of stability, stability, photocytotoxic efficiency, biodistribution and therapeutic efficiency.
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Versatile photosensitizers for photodynamic therapy at infrared excitation.
TL;DR: A new type of photosensitizers used in photodynamic therapy, which is based on photon upconverting nanoparticles, is reported that is excitable with infrared irradiation, which has several times larger tissue penetration depth than the currently available ones.
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Release of hydrophobic molecules from polymer micelles into cell membranes revealed by Förster resonance energy transfer imaging
TL;DR: The results suggest a membrane-mediated pathway for cellular uptake of hydrophobic molecules preloaded in polymeric micelles, and a putative role of the PEG shell in the molecular transport from micelle to membrane is discussed.