Journal ArticleDOI
Visualizing of skin chromophore concentrations by use of RGB images
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TLDR
In vivo imaging of a human hand during forearm occlusion and Monte Carlo simulation of light transport specifies a relation between the chromophore concentrations and Commission Internationale de l'Eclairage XYZ, which are compatible with the common RGB working space.Abstract:
A method is proposed for visualizing simply the concentrations of melanin, oxygenated blood, and deoxygenated blood in skin tissue using digital RGB images. The total blood concentration and oxygen saturation can also be reconstructed. Monte Carlo simulation of light transport specifies a relation between the chromophore concentrations and Commission Internationale de l'Eclairage XYZ, which are compatible with the common RGB working space. Experiments with a tissuelike agar gel phantom demonstrated the possibility of the method. In vivo imaging of a human hand during forearm occlusion demonstrated the ability of the method to evaluate hemodynamics of skin tissue.read more
Citations
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New principle for measuring arterial blood oxygenation, enabling motion-robust remote monitoring.
TL;DR: This work claims to be the first method to reliably measure SpO2 remotely during significant subject motion using the new ratio-of-ratios measurement principle, i.e. that the optimal signature remains the same when the SNR of the PPG signal drops significantly due to motion or limited measurement area.
Journal ArticleDOI
Materials used to simulate physical properties of human skin
A. K. Dąbrowska,G.-M. Rotaru,S. Derler,Fabrizio Spano,Martin Camenzind,Simon Annaheim,Rolf Stämpfli,Michel Schmid,René M. Rossi +8 more
TL;DR: For many applications in research, material development and testing, physical skin models are preferable to the use of human skin, because more reliable and reproducible results can be obtained.
Journal ArticleDOI
Non-contact measurement of oxygen saturation with an RGB camera
Alessandro Guazzi,Mauricio Villarroel,João Jorge,Jonathan Daly,Matthew C. Frise,Peter A. Robbins,Lionel Tarassenko +6 more
TL;DR: A novel method is presented to track oxygen saturation changes in a controlled environment using an RGB camera placed approximately 1.5 m away from the subject and carefully selects regions of interest in the camera image by calculating signal-to-noise ratios for each ROI.
Journal ArticleDOI
Noninvasive imaging of human skin hemodynamics using a digital red-green-blue camera
Izumi Nishidate,Noriyuki Tanaka,Tatsuya Kawase,Takaaki Maeda,Tomonori Yuasa,Yoshihisa Aizu,Tetsuya Yuasa,Kyuichi Niizeki +7 more
TL;DR: The results presented in the present paper indicate the possibility of visualizing the hemodynamics of subsurface skin tissue as well as the ability of the developed method to quantitatively visualize the transition from an oxygenated blood to a deoxygenated blood in dermis.
Journal ArticleDOI
Surgical spectral imaging
TL;DR: Wider sensor availability and miniaturisation are pushing speed/resolution limits and data-driven analysis avoids modelling, improves speed, addresses uncertainty, and clinical validation with standardised devices and data needed for translation.
References
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MCML-Monte Carlo modeling of light transport in multi-layered tissues
TL;DR: A Monte Carlo model of steady-state light transport in multi-layered tissues (MCML) has been coded in ANSI Standard C; therefore, the program can be used on various computers and has been in the public domain since 1992.
Journal ArticleDOI
MCML—Monte Carlo modeling of light transport in multi-layered tissues
TL;DR: A Monte Carlo model of steady-state light transport in multi-layered tissues (MCML) has been coded in ANSI Standard C; therefore, the program can be used on various computers as mentioned in this paper.
Journal ArticleDOI
Simultaneous imaging of total cerebral hemoglobin concentration, oxygenation, and blood flow during functional activation.
Andrew K. Dunn,Anna Devor,Hayrunnisa Bolay,Mark L. Andermann,Michael A. Moskowitz,Anders M. Dale,David A. Boas +6 more
TL;DR: The ability to image blood flow and hemoglobin concentration changes simultaneously with high resolution will permit detailed quantitative analysis of the spatiotemporal hemodynamics of functional brain activation, including imaging of oxygen metabolism.
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In vivo determination of optical properties of normal and tumor tissue with white light reflectance and an empirical light transport model during endoscopy
Paulo R. Bargo,Scott A. Prahl,Teresa Tarnowski Goodell,R. A. Sleven,G. Koval,G. Blair,Steven L. Jacques +6 more
TL;DR: A spatially resolved steady-state diffuse reflectance method where only two fibers (one source and one detector) spaced 2.5 mm apart are used for the determination of the optical properties, which is suited for endoscopic measurements.
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A comparison of angiotensin-converting enzyme inhibitors, calcium antagonists, beta-blockers and diuretic agents on reactive hyperemia in patients with essential hypertension: A multicenter study
Yukihito Higashi,Shota Sasaki,Keigo Nakagawa,Tomohiro Ueda,Atsunori Yoshimizu,Satoshi Kurisu,Hideo Matsuura,Goro Kajiyama,Tetsuya Oshima +8 more
TL;DR: It is suggested that ACE inhibitors augment reactive hyperemia, an index of endothelium-dependent vasorelaxation, in patients with essential hypertension.