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Open AccessJournal ArticleDOI

Vitamin D in pregnancy and lactation: maternal, fetal, and neonatal outcomes from human and animal studies

TLDR
Dosing recommendations for women during pregnancy and lactation might be best directed toward ensuring that the neonate is vitamin D-sufficient and that this sufficiency is maintained during infancy and beyond.
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This article is published in The American Journal of Clinical Nutrition.The article was published on 2008-08-01 and is currently open access. It has received 314 citations till now. The article focuses on the topics: vitamin D deficiency & Rickets.

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Citations
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Journal ArticleDOI

Vitamin D for Health: A Global Perspective

TL;DR: There is potentially a great upside to increasing the vitamin D status of children and adults worldwide for improving musculoskeletal health and reducing the risk of chronic illnesses, including some cancers, autoimmune diseases, infectious diseases, type 2 diabetes mellitus, neurocognitive disorders and mortality.
Journal ArticleDOI

Implications of vitamin D deficiency in pregnancy and lactation

TL;DR: This review discusses vitamin D metabolism and the implications of vitamin D deficiency in pregnancy and lactation and the recommended daily doses in pregnant women and breastfed infants.
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Maternal early pregnancy vitamin D status in relation to fetal and neonatal growth: results of the multi-ethnic Amsterdam Born Children and their Development cohort.

TL;DR: Although a deficient vitamin D status influenced birth weight, SGA risk and neonatal growth, it played a limited role in explaining ethnic differences and more research is needed before a nationwide policy on the subject can be justified.
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Vitamin D and fertility: a systematic review.

TL;DR: Evidence that vitamin D is involved in female reproduction including IVF outcome (clinical pregnancy rates) and polycystic ovary syndrome (PCOS) is presented and vitamin D supplementation might improve menstrual frequency and metabolic disturbances in women.
References
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Journal ArticleDOI

Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study

TL;DR: Vitamin D supplementation was associated with a decreased frequency of type 1 diabetes when adjusted for neonatal, anthropometric, and social characteristics and Ensuring adequate vitamin D supplementation for infants could help to reverse the increasing trend in the incidence ofType 1 diabetes.
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Hypovitaminosis D is associated with insulin resistance and β cell dysfunction

TL;DR: A positive correlation of 25(OH)D concentration with insulin sensitivity and a negative effect of hypovitaminosis D on beta cell function are shown, which are at higher risk of insulin resistance and the metabolic syndrome.

Hypovitaminosis D is associated with insulin resistance and cell

TL;DR: In this paper, the relation of 25-hydroxyvitamin D [25(OH)D] concentrations to insulin sensitivity and cell function was investigated, and the results showed that 25-OHD concentration was positively correlated with ISI (P 0.0001) and negatively correlated with 1st and second-phase insulin responses (1stIR and 2ndIR).
Journal ArticleDOI

Targeted ablation of the vitamin d receptor : an animal model of vitamin d-dependent rickets type ii with alopecia

TL;DR: A mouse model of VDDR II is generated by targeted ablation of the second zinc finger of the VDR DNA-binding domain and homozygous mice are phenotypically normal at birth and demonstrate normal survival at least until 6 months, compared to animals made vitamin D deficient by dietary means.
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