Journal ArticleDOI
Westernized diets lower arsenic gastrointestinal bioaccessibility but increase microbial arsenic speciation changes in the colon.
TLDR
Dietary background is a crucial parameter to incorporate when predicting bioavailability with bioaccessibility measurements and when assessing health risks from As following oral exposure.About:
This article is published in Chemosphere.The article was published on 2015-01-01. It has received 40 citations till now.read more
Citations
More filters
Journal ArticleDOI
Arsenic and Environmental Health: State of the Science and Future Research Opportunities
Danielle J Carlin,Marisa F. Naujokas,Karen D. Bradham,John Cowden,Michelle Heacock,Heather F Henry,Janice S. Lee,David J. Thomas,Claudia Thompson,Erik J. Tokar,Michael P. Waalkes,Linda S. Birnbaum,William A. Suk +12 more
TL;DR: A review of emerging issues and research needs to address the multi-faceted challenges related to arsenic and environmental health and suggests integration of omics data with mechanistic and epidemiological data is a key step toward the goal of linking biomarkers of exposure and susceptibility to disease mechanisms and outcomes.
Journal ArticleDOI
Arsenic in the human food chain, biotransformation and toxicology- review focusing on seafood arsenic
TL;DR: Recent findings indicate that the pre-systematic metabolism by colon microbiota play an important role for human metabolism of arsenicals, and new insight indicates that bioconversion of arsenosugars and arsenolipids in seafood results in urinary excretion of DMA, possibly also producing reactive trivalent arsenic intermediates.
Journal ArticleDOI
Arsenic: A Review of the Element’s Toxicity, Plant Interactions, and Potential Methods of Remediation
TL;DR: An assessment of the literature indicates that controlling contamination of water sources and plants through effective remediation and management is essential to successfully addressing the problems of arsenic toxicity and contamination.
Journal ArticleDOI
Arsenic Accumulation in Rice and Probable Mitigation Approaches: A Review
TL;DR: Common agronomical practices like rain water harvesting for crop irrigation, use of natural components that help in arsenic methylation, and biotechnological approaches may explore how to reduce arsenic uptake by food crops.
Journal ArticleDOI
Gut microbiota: A target for heavy metal toxicity and a probiotic protective strategy.
TL;DR: This review is a summary of the bidirectional relationship between HMs and gut microbiota and of the probiotic-based protective strategies against HM-induced gut dysbiosis, with reference to strategies used in the food industry or for medically alleviating HM toxicity.
References
More filters
Journal ArticleDOI
Characterization of the intestinal absorption of arsenate, monomethylarsonic acid, and dimethylarsinic acid using the Caco-2 cell line.
TL;DR: Examination of absorption through the intestinal epithelium of the pentavalent arsenic species most commonly found in foods, using the Caco-2 cell line as a model, constitutes the basis for future research on the mechanisms involved in the intestinal absorption of arsenic and its species.
Journal ArticleDOI
Heat-Assisted Aqueous Extraction of Rice Flour for Arsenic Speciation Analysis
Tomohiro Narukawa,Koichi Chiba +1 more
TL;DR: A versatile heat-assisted pretreatment aqueous extraction method for the analysis of arsenic species in rice was developed and the sums of the concentrations of all species in each rice flour sample were 97-102% of the total arsenic concentration in each sample.
Journal ArticleDOI
HPLC-ICP-MS method development to monitor arsenic speciation changes by human gut microbiota.
TL;DR: The biotransformation of arsenic (As) is studied using a Simulator of the Human Intestinal Microbial Ecosystem (SHIME) using a method using liquid chromatography hyphenated to an inductively coupled plasma mass spectrometer (HPLC-ICP-MS), which allowed successful quantification of arsenic species in suspensions sampled in vitro from the SHIME reactor or in vivo from the human colon and feces.
Journal ArticleDOI
Arsenic undergoes significant speciation changes upon incubation of contaminated rice with human colon micro biota
TL;DR: In vitro study of gut microbial metabolism affects As in different rice matrices suggested that presystemic metabolism by human gut micro biota should be neglected in risk assessment studies.
Journal ArticleDOI
Biotransformation of metal(loid)s by intestinal microorganisms
TL;DR: The gut microbial potency should be considered to be taken up in toxicokinetic studies and models for assessing the health risks of oral metal(loid) exposure, to allow the relevance of intestinal metal( loid) biotransformation to be assessed for human health risks.