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Andreas Bender
Researcher at Ludwig Maximilian University of Munich
Publications - 138
Citations - 5613
Andreas Bender is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Minimally conscious state & Mitochondrial DNA. The author has an hindex of 34, co-authored 127 publications receiving 4699 citations. Previous affiliations of Andreas Bender include University of California, San Diego & University of Oxford.
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Journal ArticleDOI
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease.
Andreas Bender,Kim J. Krishnan,Christopher Morris,Geoffrey A. Taylor,Amy K. Reeve,Robert H. Perry,Evelyn Jaros,Joshua S Hersheson,Joanne Betts,Thomas Klopstock,Robert W. Taylor,Douglass M. Turnbull +11 more
TL;DR: It is shown that in substantia nigra neurons from both aged controls and individuals with Parkinson disease, there is a high level of deleted mitochondrial DNA, suggesting that somatic mtDNA deletions are important in the selective neuronal loss observed in brain aging and in Parkinson disease.
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A pharmacological model for psychosis based on N-methyl-D-aspartate receptor hypofunction : Molecular, cellular, functional and behavioral abnormalities
Dan Rujescu,Andreas Bender,Martin E. Keck,Annette M. Hartmann,Frauke Ohl,Hanna Raeder,Ina Giegling,Just Genius,Robert W. McCarley,Hans-Jürgen Möller,Heinz Grunze +10 more
TL;DR: Animal models for psychosis based on a glutamatergic approach have a significant potential of serving as a model of the pathobiology of several aspects of psychosis and consequently could contribute to the development of new therapeutic strategies.
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European Academy of Neurology guideline on the diagnosis of coma and other disorders of consciousness
Daniel Kondziella,Daniel Kondziella,Daniel Kondziella,Andreas Bender,Karin Diserens,W.S. van Erp,Anna Estraneo,Rita Formisano,Steven Laureys,Lionel Naccache,Şerefnur Öztürk,Benjamin Rohaut,Benjamin Rohaut,Jacobo D. Sitt,Johan Stender,Marjaana Tiainen,Andrea O. Rossetti,Olivia Gosseries,Camille Chatelle +18 more
TL;DR: This guideline provides the state‐of‐the‐art evidence regarding the diagnosis of DoC, summarizing data from bedside examination techniques, functional neuroimaging and electroencephalography (EEG).
Journal ArticleDOI
Creatine supplementation in Parkinson disease: a placebo-controlled randomized pilot trial.
Andreas Bender,W. Koch,Matthias Elstner,Y. Schombacher,Julia Bender,M. Moeschl,F. Gekeler,Bertram Müller-Myhsok,T. Gasser,Klaus Tatsch,Thomas Klopstock +10 more
TL;DR: Creatine improved patient mood and led to a smaller dose increase of dopaminergic therapy but had no effect on overall Unified Parkinson's Disease Rating Scale scores or dopamine transporter SPECT.
Journal ArticleDOI
Expression analysis of dopaminergic neurons in Parkinson's disease and aging links transcriptional dysregulation of energy metabolism to cell death
Matthias Elstner,Matthias Elstner,Christopher Morris,Katharina Heim,Andreas Bender,Divya Mehta,Evelyn Jaros,Thomas Klopstock,Thomas Meitinger,Thomas Meitinger,Douglass M. Turnbull,Holger Prokisch,Holger Prokisch +12 more
TL;DR: In this article, the authors used a laser capture microdissection to isolate dopamine neurons from the substantia nigra pars compacta of PD patients, age-matched and young controls to determine transcriptional changes by expression profiling and pathway analysis.