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Andrew D. Ellington
Researcher at University of Texas at Austin
Publications - 599
Citations - 48723
Andrew D. Ellington is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Aptamer & RNA. The author has an hindex of 96, co-authored 569 publications receiving 43262 citations. Previous affiliations of Andrew D. Ellington include Harvard University & UPRRP College of Natural Sciences.
Papers
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PatentDOI
T7 rna polymerase variants with expanded substrate range and enhanced transcriptional yield
TL;DR: In this article, mutations that increase the transcriptional activity of the variants with broad substrate range are presented, with a focus on T7 RNA polymerase variants with enhanced transcriptional activities.
Journal ArticleDOI
Developing RNA Tools for Engineered Regulatory Systems
TL;DR: This work considers the natural RNA tools and mechanisms that are available to researchers, then examines how these tools are being applied in artificial genetic circuits, potentially including ’smart’ nucleic acid drugs that regulate their own production and release.
Journal ArticleDOI
WWW Guide: Shopping for Biotechnology Products on the Web: A User's Guide
Journal Article
Targeting PSMA on tumor cells using novel aptamer-gelonin conjugates
Andrew D. Ellington,John W. Marks,Ted C. Chu,Laura A. Lavery,Sarah Faulkner,Matthew Levy,Michael G. Rosenblum +6 more
TL;DR: It is suggested that aptamers can be used to successfully deliver protein molecules such as toxins to tumor cells and may provide a novel approach to development of targeted therapeutic agents.
Patent
Thermostable reverse transcriptase
TL;DR: In this article, the authors discuss methods and compositions related to the generation and/or use of proofreading reverse transcriptases, including those that are thermophilic or hyperthermophilic.