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Andrew D. Ellington
Researcher at University of Texas at Austin
Publications - 599
Citations - 48723
Andrew D. Ellington is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Aptamer & RNA. The author has an hindex of 96, co-authored 569 publications receiving 43262 citations. Previous affiliations of Andrew D. Ellington include Harvard University & UPRRP College of Natural Sciences.
Papers
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Journal ArticleDOI
Transiently transfected purine biosynthetic enzymes form stress bodies.
Alice X.H. Zhao,Mark Tsechansky,Jagannath Swaminathan,Lindsey Cook,Andrew D. Ellington,Edward M. Marcotte +5 more
TL;DR: It is demonstrated that intracellular bodies formed by transiently transfected, fluorescently tagged human purine biosynthesis proteins are best explained as protein aggregation.
Journal ArticleDOI
Aptamer antagonists of myelin-derived inhibitors promote axon growth.
TL;DR: It is shown that RNA aptamers can be generated that bind with high affinity to NgR, compete with myelin-derived inhibitors for binding to Ngr, and promote axon elongation of neurons in vitro even in the presence of these inhibitors.
Journal ArticleDOI
Erratum: Aptamers as therapeutics
TL;DR: In this paper, the address of X-Chem Incorporated, 100 Beaver Street, Waltham, Massachusetts 02453, USA, was incorrectly given for Keefe. But the correct address is: X-chem Incorporated.
Journal ArticleDOI
Changing the Cofactor Diet of an Enzyme
TL;DR: In their Perspective, Ellington and Bull discuss how a five-amino acid change in the enzyme switches the cofactor to NADP, with normal activity in vitro, explaining the conservation of cofactor specificities in natural enzymes.
Patent
Methods and devices related to toehold-based strand displacement with loop-mediated isothermal amplification
Andrew D. Ellington,Yu Sherry Jiang,Sanchita Bhadra,Bingling Li,Randy Allen Hughes,Yan Du,Jimmy Gollihar +6 more
TL;DR: In this paper, compositions and methods for isothermal nucleic acid amplification and detection are described and discussed. But none of the methods are suitable for the detection of nucleic acids.