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Andrew D. Ellington
Researcher at University of Texas at Austin
Publications - 599
Citations - 48723
Andrew D. Ellington is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Aptamer & RNA. The author has an hindex of 96, co-authored 569 publications receiving 43262 citations. Previous affiliations of Andrew D. Ellington include Harvard University & UPRRP College of Natural Sciences.
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Journal ArticleDOI
Applications of Aptamers as Sensors
TL;DR: Aptamers are ligand-binding nucleic acids whose affinities and selectivities can rival those of antibodies, and they are readily adapted to sequence- (and hence signal-) amplification methods.
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Aptamer beacons for the direct detection of proteins.
TL;DR: Aptamer beacon can be a sensitive tool for detecting proteins and other chemical compounds and a fluorescence-quenching pair is used to report changes in conformation induced by ligand binding.
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Engineering Escherichia coli to see light
Anselm Levskaya,Aaron Chevalier,Jeffrey J. Tabor,Zachary B. Simpson,Laura A. Lavery,Matthew Levy,Eric A. Davidson,Alexander D. Scouras,Andrew D. Ellington,Edward M. Marcotte,Christopher A. Voigt,Christopher A. Voigt +11 more
TL;DR: In this paper, the authors designed a bacterial system that is switched between different states by red light, such that the projection of a pattern of light on to the bacteria produces a high-definition (about 100 megapixels per square inch), two-dimensional chemical image.
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Nucleic Acid Selection and the Challenge of Combinatorial Chemistry
Journal ArticleDOI
A synthetic genetic edge detection program.
Jeffrey J. Tabor,Howard M. Salis,Zachary B. Simpson,Aaron Chevalier,Anselm Levskaya,Edward M. Marcotte,Christopher A. Voigt,Andrew D. Ellington +7 more
TL;DR: A genetically encoded edge detection algorithm is constructed that programs an isogenic community of E. coli to sense an image of light, communicate to identify the light-dark edges, and visually present the result of the computation.