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Andrew D. Ellington
Researcher at University of Texas at Austin
Publications - 599
Citations - 48723
Andrew D. Ellington is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Aptamer & RNA. The author has an hindex of 96, co-authored 569 publications receiving 43262 citations. Previous affiliations of Andrew D. Ellington include Harvard University & UPRRP College of Natural Sciences.
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Journal ArticleDOI
Elucidation of the initial step of oligonucleotide fragmentation in matrix-assisted laser desorption/ionization using modified nucleic acids
TL;DR: Analysis of modifications of modified oligonucleotides suggests that the initial fragmentation step in MALDI-MS involves a two-step elimination of the base.
Journal ArticleDOI
Direct nucleic acid analysis of mosquitoes for high fidelity species identification and detection of Wolbachia using a cellphone.
Sanchita Bhadra,Timothy E. Riedel,Miguel A. Saldaña,Shivanand Hegde,Nicole Pederson,Grant L. Hughes,Andrew D. Ellington +6 more
TL;DR: Modest technology requirements, minimal execution steps, simple binary readout, and robust accuracy make the LAMP-OSD-to-cellphone assay platform well suited for field vector surveillance in austere or resource-limited conditions.
Journal ArticleDOI
Revisiting and revising the purinosome
TL;DR: New discoveries challenge both the functional and physiological relevance of these bodies-cytoplasmic puncta containing transfected purine biosynthesis enzymes in favor of protein aggregation.
Journal ArticleDOI
Protective effects of anti-ricin A-chain RNA aptamer against ricin toxicity.
TL;DR: In this article, the anti-RTA RNA aptamer can protect against ricin ribotoxicity in cell-based luciferase and cell cytotoxicity assays, which represents a novel class of nucleic acid inhibitor that has the potential to be developed as a therapeutic agent for the treatment of ricin intoxication.
PatentDOI
3d printing with nucleic acid adhesives
TL;DR: By relying on specific DNA:DNA interactions as a “smart glue”, microparticles are assembled into a colloidal gel that can hold its shape and should provide a new means of engineering bioprinted tissues.