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Arna B Agustsdottir
Researcher at Amgen
Publications - 13
Citations - 2518
Arna B Agustsdottir is an academic researcher from Amgen. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 8, co-authored 13 publications receiving 1973 citations.
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Journal ArticleDOI
Spread of SARS-CoV-2 in the Icelandic Population.
Daniel F. Gudbjartsson,Agnar Helgason,Hakon Jonsson,Olafur T. Magnusson,Páll Melsted,Gudmundur L. Norddahl,Jona Saemundsdottir,Asgeir Sigurdsson,Patrick Sulem,Arna B Agustsdottir,Berglind Eiriksdottir,Run Fridriksdottir,Elisabet E Gardarsdottir,Gudmundur Georgsson,Olafia S Gretarsdottir,Kjartan R Gudmundsson,Thora R Gunnarsdottir,Arnaldur Gylfason,Hilma Holm,Brynjar O. Jensson,Aslaug Jonasdottir,Frosti Jonsson,Kamilla S Josefsdottir,Thordur Kristjansson,Droplaug N Magnusdottir,Louise le Roux,Gudrun Sigmundsdottir,Gardar Sveinbjornsson,Kristin E Sveinsdottir,Maney Sveinsdottir,Emil A Thorarensen,Bjarni Thorbjornsson,Arthur Löve,Gisli Masson,Ingileif Jonsdottir,Alma D. Möller,Thorolfur Gudnason,Karl G. Kristinsson,Unnur Thorsteinsdottir,Kari Stefansson +39 more
TL;DR: In a population-based study in Iceland, children under 10 years of age and females had a lower incidence of SARS-CoV-2 infection than adolescents or adults and males and the proportion of infected participants identified through population screening remained stable for the 20-day duration of screening.
Journal ArticleDOI
Humoral Immune Response to SARS-CoV-2 in Iceland.
Daniel F. Gudbjartsson,Gudmundur L. Norddahl,Páll Melsted,Kristbjorg Gunnarsdottir,Hilma Holm,Elias Eythorsson,Asgeir O. Arnthorsson,Dadi Helgason,Kristbjorg Bjarnadottir,Ragnar Freyr Ingvarsson,Brynja Thorsteinsdottir,Steinunn Kristjánsdóttir,Kolbrun Birgisdottir,Anna M. Kristinsdottir,Martin I. Sigurdsson,Gudny A. Arnadottir,Erna V. Ivarsdottir,Margret B. Andresdottir,Frosti Jonsson,Arna B Agustsdottir,Jonas Berglund,Berglind Eiriksdottir,Run Fridriksdottir,Elisabet E Gardarsdottir,Magnus Gottfredsson,Olafia S Gretarsdottir,Steinunn Gudmundsdottir,Kjartan R Gudmundsson,Thora R Gunnarsdottir,Arnaldur Gylfason,Agnar Helgason,Brynjar O. Jensson,Aslaug Jonasdottir,Hakon Jonsson,Thordur Kristjansson,Karl G. Kristinsson,Droplaug N Magnusdottir,Olafur T. Magnusson,Lovisa Bjork Olafsdottir,Solvi Rognvaldsson,Louise le Roux,Gudrun Sigmundsdottir,Asgeir Sigurdsson,Gardar Sveinbjornsson,Kristin E Sveinsdottir,Maney Sveinsdottir,Emil A Thorarensen,Bjarni Thorbjornsson,Marianna Thordardottir,Jona Saemundsdottir,S Hjortur Kristjansson,Kamilla S Josefsdottir,Gisli Masson,Gudmundur Georgsson,Mar Kristjansson,Alma D. Möller,Runolfur Palsson,Thorolfur Gudnason,Unnur Thorsteinsdottir,Ingileif Jonsdottir,Patrick Sulem,Kari Stefansson +61 more
TL;DR: The authors' results indicate that antiviral antibodies against SARS-CoV-2 did not decline within 4 months after diagnosis, and antiviral antibody titers assayed by two pan-Ig assays remained on a plateau for the remainder of the study.
Journal ArticleDOI
Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease
Paul Nioi,Asgeir Sigurdsson,Gudmar Thorleifsson,Hannes Helgason,Arna B Agustsdottir,Gudmundur L. Norddahl,Anna Helgadottir,Audur Magnusdottir,Aslaug Jonasdottir,Solveig Gretarsdottir,Ingileif Jonsdottir,Valgerdur Steinthorsdottir,Thorunn Rafnar,Dorine W. Swinkels,Tessel E. Galesloot,Niels Grarup,Torben Jørgensen,Henrik Vestergaard,Torben Hansen,Torsten Lauritzen,Allan Linneberg,Nele Friedrich,Nikolaj T. Krarup,Mogens Fenger,Ulrik Abildgaard,Peter Riis Hansen,Anders Galløe,Anders Galløe,Peter S. Braund,Christopher P. Nelson,Alistair S. Hall,Michael J.A. Williams,Andre M. van Rij,Gregory T. Jones,Riyaz S. Patel,Allan I Levey,Salim S. Hayek,Svati H. Shah,Muredach P. Reilly,Gudmundur I. Eyjolfsson,Olof Sigurdardottir,Isleifur Olafsson,Lambertus A. Kiemeney,Arshed A. Quyyumi,Daniel J. Rader,William E. Kraus,Nilesh J. Samani,Oluf Pedersen,Gudmundur Thorgeirsson,Gisli Masson,Hilma Holm,Daniel F. Gudbjartsson,Patrick Sulem,Unnur Thorsteinsdottir,Kari Stefansson +54 more
TL;DR: ASGR1 haploinsufficiency was associated with reduced levels of non-HDL cholesterol and a reduced risk of coronary artery disease, and a rare noncoding 12-base-pair deletion in intron 4 of ASGR1 was found.
Journal ArticleDOI
A homozygous loss-of-function mutation leading to CYBC1 deficiency causes chronic granulomatous disease
Gudny A. Arnadottir,Gudmundur L. Norddahl,Steinunn Gudmundsdottir,Arna B Agustsdottir,Snaevar Sigurdsson,Brynjar O. Jensson,Kristbjorg Bjarnadottir,Fannar Theodors,Stefania Benonisdottir,Erna V. Ivarsdottir,Erna V. Ivarsdottir,Asmundur Oddsson,Ragnar P. Kristjansson,Gerald Sulem,Kristjan F. Alexandersson,Thorhildur Juliusdottir,Kjartan R Gudmundsson,Jona Saemundsdottir,Adalbjorg Jonasdottir,Aslaug Jonasdottir,Asgeir Sigurdsson,Paolo Manzanillo,Sigurjon A. Gudjonsson,Gudmundur A. Thorisson,Olafur Th Magnusson,Gisli Masson,Kjartan B. Orvar,Hilma Holm,Sigurdur Bjornsson,Reynir Arngrímsson,Daniel F. Gudbjartsson,Daniel F. Gudbjartsson,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Ingileif Jonsdottir,Ingileif Jonsdottir,Ásgeir Haraldsson,Ásgeir Haraldsson,Patrick Sulem,Kari Stefansson,Kari Stefansson +40 more
TL;DR: It is found that CYBC1 deficiency results in CGD characterized by colitis and a distinct profile of infections indicative of macrophage dysfunction, and is important for formation of the NADPH complex and respiratory burst.
Posted ContentDOI
Early Spread of SARS-Cov-2 in the Icelandic Population
Daniel F. Gudbjartsson,Daniel F. Gudbjartsson,Agnar Helgason,Agnar Helgason,Hakon Jonsson,Olafur Th Magnusson,Páll Melsted,Páll Melsted,Gudmundur L. Norddahl,Jona Saemundsdottir,Asgeir Sigurdsson,Patrick Sulem,Arna B Agustsdottir,Berglind Eiriksdottir,Run Fridriksdottir,Elisabet E Gardarsdottir,Gudmundur Georgsson,Olafia S Gretarsdottir,Kjartan R Gudmundsson,Thora R Gunnarsdottir,Arnaldur Gylfason,Hilma Holm,Brynjar O. Jensson,Aslaug Jonasdottir,Frosti Jonsson,Kamilla S Josefsdottir,Thordur Kristjansson,Droplaug N Magnusdottir,Louise le Roux,Gudrun Sigmundsdottir,Gardar Sveinbjornsson,Kristin E Sveinsdottir,Maney Sveinsdottir,Emil A Thorarensen,Bjarni Thorbjornsson,Arthur Löve,Gisli Masson,Ingileif Jonsdottir,Ingileif Jonsdottir,Alma D. Möller,Thorolfur Gudnason,Karl G. Kristinsson,Karl G. Kristinsson,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Kari Stefansson,Kari Stefansson +46 more
TL;DR: SARS-CoV-2 has spread widely in Iceland outside of the high-risk groups and to contain the pandemic the authors must increase the scope of the testing.