N
Nele Friedrich
Researcher at University of Greifswald
Publications - 124
Citations - 7310
Nele Friedrich is an academic researcher from University of Greifswald. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 34, co-authored 101 publications receiving 6626 citations. Previous affiliations of Nele Friedrich include Greifswald University Hospital & University of Copenhagen.
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Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
Elizabeth K. Speliotes,Cristen J. Willer,Sonja I. Berndt,Keri L. Monda,Gudmar Thorleifsson,Anne U. Jackson,H Lango Allen,Cecilia M. Lindgren,Jian'an Luan,Reedik Mägi,Joshua C. Randall,Sailaja Vedantam,Thomas W. Winkler,Lu Qi,Tsegaselassie Workalemahu,Iris M. Heid,Valgerdur Steinthorsdottir,Heather M. Stringham,Michael N. Weedon,Eleanor Wheeler,Andrew R. Wood,Teresa Ferreira,Robert J. Weyant,Ayellet V. Segrè,K. Estrada,Liming Liang,James Nemesh,Ju-Hyun Park,Stefan Gustafsson,Tuomas O. Kilpeläinen,Jian Yang,Nabila Bouatia-Naji,Tõnu Esko,Mary F. Feitosa,Zoltán Kutalik,Massimo Mangino,Soumya Raychaudhuri,André Scherag,Albert V. Smith,Ryan P. Welch,Jing Hua Zhao,Katja K.H. Aben,Devin Absher,Najaf Amin,Anna L. Dixon,Eva Fisher,Nicole L. Glazer,Michael E. Goddard,Nancy L. Heard-Costa,Volker Hoesel,Jouke-Jan Hottenga,Åsa Johansson,Toby Johnson,Shamika Ketkar,Claudia Lamina,Shengxu Li,MF Moffatt,Richard H. Myers,Narisu Narisu,John R. B. Perry,Maire Peters,Michael Preuss,Samuli Ripatti,Fernando Rivadeneira,Camilla H. Sandholt,Laura J. Scott,Nicholas J. Timpson,Jonathan Tyrer,S. van Wingerden,Richard M. Watanabe,Charles L. White,Fredrik Wiklund,Cristina Barlassina,Daniel I. Chasman,Mark E. Cooper,John-Olov Jansson,Robert W. Lawrence,Niina Pellikka,Inga Prokopenko,Jianxin Shi,Elisabeth Thiering,Helene Alavere,Maria Teresa Sciarrone Alibrandi,Peter Almgren,Andreas Arnold,Thor Aspelund,Larry D. Atwood,Beverley Balkau,Anthony J. Balmforth,Amanda J. Bennett,Yoav Ben-Shlomo,Richard N. Bergman,Sven Bergmann,Heike Biebermann,Alexandra I. F. Blakemore,Tanja Boes,Lori L. Bonnycastle,Stefan R. Bornstein,Michael Brown,Thomas A. Buchanan,Fabio Busonero,Harry Campbell,Francesco P. Cappuccio,Christine Cavalcanti-Proença,Y. D. Chen,C. M. Chen,Peter S. Chines,Robert Clarke,Lachlan J. M. Coin,John M. C. Connell,Ian N.M. Day,M. den Heijer,Jubao Duan,Shah Ebrahim,Paul Elliott,Roberto Elosua,G. Eiriksdottir,Mike Erdos,Johan G. Eriksson,Maurizio Facheris,Stephan B. Felix,Pamela Fischer-Posovszky,Aaron R. Folsom,Nele Friedrich,Nelson B. Freimer,Mao Fu,Stéphane Gaget,Pablo V. Gejman,Eco J. C. de Geus,Christian Gieger,Anette P. Gjesing,Anuj Goel,Philippe Goyette,Harald Grallert,Jürgen Grässler,Danielle M. Greenawalt,C J Groves,Vilmundur Gudnason,Candace Guiducci,A.-L. Hartikainen,N Hassanali,Alistair S. Hall,Aki S. Havulinna,Caroline Hayward,Andrew C. Heath,Christian Hengstenberg,Andrew A. Hicks,Anke Hinney,Albert Hofman,G. Homuth,Jennie Hui,Wilmar Igl,Carlos Iribarren,Bo Isomaa,Kevin B. Jacobs,Ivonne Jarick,Elizabeth S. Jewell,Ulrich John,Torben Jørgensen,P. Jousilahti,A. Jula,Marika Kaakinen,Eero Kajantie,Lee M. Kaplan,Sekar Kathiresan,Johannes Kettunen,Leena Kinnunen,Joshua W. Knowles,Ivana Kolcic,Inke R. König,Seppo Koskinen,Peter Kovacs,Johanna Kuusisto,Peter Kraft,Kirsti Kvaløy,Jaana Laitinen,Olivier Lantieri,Chiara Lanzani,Lenore J. Launer,Cécile Lecoeur,Terho Lehtimäki,Guillaume Lettre,Jianjun Liu,Marja-Liisa Lokki,Mattias Lorentzon,Robert Luben,Barbara Ludwig,Paolo Manunta,Diana Marek,Michel Marre,Nicholas G. Martin,Wendy L. McArdle,Alun D. McCarthy,Barbara McKnight,Thomas Meitinger,Olle Melander,David Meyre,Kristian Midthjell,Grant W. Montgomery,M. A. Morken,Andrew P. Morris,Rosanda Mulić,Julius S. Ngwa,Mari Nelis,Matt Neville,Dale R. Nyholt,Christopher J. O'Donnell,Stephen O'Rahilly,Ken K. Ong,Ben A. Oostra,Guillaume Paré,Alex N. Parker,Markus Perola,Irene Pichler,Kirsi H. Pietiläinen,Carl Platou,Ozren Polasek,A Pouta,Suzanne Rafelt,Olli T. Raitakari,Nigel W. Rayner,Martin Ridderstråle,Winfried Rief,Aimo Ruokonen,Neil R. Robertson,Peter Rzehak,Veikko Salomaa,Alan R. Sanders,Manjinder S. Sandhu,Serena Sanna,Jouko Saramies,Markku J. Savolainen,S. Scherag,Sabine Schipf,Stefan Schreiber,Heribert Schunkert,Kaisa Silander,Juha Sinisalo,David S. Siscovick,J.H. Smit,Nicole Soranzo,Ulla Sovio,J. Stephens,Ida Surakka,Amy J. Swift,M. L. Tammesoo,Jean-Claude Tardif,Maris Teder-Laving,Tanya M. Teslovich,John R. Thompson,Brian Thomson,A Tönjes,Tiinamaija Tuomi,J.B. van Meurs,G.J.B. van Ommen,Vincent Vatin,Jorma Viikari,Sophie Visvikis-Siest,Veronique Vitart,Charlotte Vogel,Benjamin F. Voight,Lindsay L. Waite,Henri Wallaschofski,G B Walters,E. Widen,Susanna Wiegand,Sarah H. Wild,Gonneke Willemsen,Daniel R. Witte,Jacqueline C. M. Witteman,Jianfeng Xu,Qunyuan Zhang,Lina Zgaga,Andreas Ziegler,P. Zitting,John Beilby,I S Farooqi,Johannes Hebebrand,Heikki V. Huikuri,Alan L. James,Mika Kähönen,Douglas F. Levinson,Fabio Macciardi,Markku S. Nieminen,Claes Ohlsson,Lyle J. Palmer,Paul M. Ridker,Michael Stumvoll,Jacques S. Beckmann,H. Boeing,Eric Boerwinkle,Dorret I. Boomsma,Mark J. Caulfield,Stephen J. Chanock,Francis S. Collins,L. A. Cupples,George Davey Smith,Jeanette Erdmann,Philippe Froguel,Henrik Grönberg,Ulf Gyllensten,Per Hall,Torben Hansen,Tamara B. Harris,Andrew T. Hattersley,Richard B. Hayes,Joachim Heinrich,Frank B. Hu,Kristian Hveem,Thomas Illig,Marjo-Riitta Järvelin,Jaakko Kaprio,Fredrik Karpe,Kay-Tee Khaw,Lambertus A. Kiemeney,Heiko Krude,Markku Laakso,Debbie A Lawlor,Andres Metspalu,Patricia B. Munroe,Willem H. Ouwehand,Oluf Pedersen,Brenda W.J.H. Penninx,Annette Peters,Peter P. Pramstaller,Thomas Quertermous,Thomas Reinehr,A. Rissanen,Igor Rudan,Nilesh J. Samani,Peter Schwarz,Alan R. Shuldiner,Tim D. Spector,Jaakko Tuomilehto,Manuela Uda,André G. Uitterlinden,Valle Tt,Martin Wabitsch,G. Waeber,Nicholas J. Wareham,Hugh Watkins,James F. Wilson,Alan F. Wright,M. C. Zillikens,Nilanjan Chatterjee,Steven A. McCarroll,Shaun Purcell,Eric E. Schadt,Peter M. Visscher,Themistocles L. Assimes,Ingrid B. Borecki,Panos Deloukas,Caroline S. Fox,Leif Groop,Talin Haritunians,David J. Hunter,Robert C. Kaplan,Karen L. Mohlke,Jeffrey R. O'Connell,Leena Peltonen,David Schlessinger,David P. Strachan,C M van Duijn,H. E. Wichmann,Timothy M. Frayling,Unnur Thorsteinsdottir,Gonçalo R. Abecasis,Inês Barroso,Michael Boehnke,Kari Stefansson,Kari E. North,Mark I. McCarthy,Joel N. Hirschhorn,Erik Ingelsson,Ruth J. F. Loos +374 more
TL;DR: 18 new loci associated with body mass index are identified, one of which includes a copy number variant near GPRC5B, and genes in other newly associated loci may provide new insights into human body weight regulation.
Journal ArticleDOI
Cohort Profile: The Study of Health in Pomerania
Henry Völzke,Dietrich Alte,Carsten Oliver Schmidt,Dörte Radke,Roberto Lorbeer,Nele Friedrich,Nicole Aumann,Katharina Lau,Michael Piontek,Gabriele Born,Christoph Havemann,Till Ittermann,Sabine Schipf,Robin Haring,Robin Haring,Sebastian E. Baumeister,Henri Wallaschofski,Matthias Nauck,Stephanie Frick,Andreas Arnold,Michael Jünger,Julia Mayerle,Matthias Kraft,Markus M. Lerch,Marcus Dörr,Thorsten Reffelmann,Klaus Empen,Stephan B. Felix,Anne Obst,Beate Koch,Sven Gläser,Ralf Ewert,Ingo Fietze,Thomas Penzel,Martina Dören,Wolfgang Rathmann,Johannes Haerting,Mario Hannemann,J Röpcke,Ulf Schminke,Clemens Jürgens,Frank Tost,Rainer Rettig,Jan A. Kors,Saskia Ungerer,K Hegenscheid,Jens Peter Kühn,Julia Kühn,Norbert Hosten,Ralf Puls,Jörg Henke,Oliver Gloger,Alexander Teumer,Georg Homuth,Uwe Völker,Christian Schwahn,Birte Holtfreter,Ines Polzer,Thomas Kohlmann,Hans J. Grabe,Dieter Rosskopf,Heyo K. Kroemer,Thomas Kocher,Reiner Biffar,Ulrich John,Wolfgang Hoffmann +65 more
TL;DR: Henry Volzke, y Dietrich Alte,1y Carsten Oliver Schmidt, Dorte Radke, Roberto Lorbeer, Nele Friedrich, Nicole Aumann, Katharina Lau, Michael Piontek, Gabriele Born, Christoph Havemann, Till Ittermann, Sabine Schipf, Robin Haring, Sebastian E Baumeister, Henri Wallaschofski, Matthias Nauck, Stephanie Frick, Andreas Arnold.
Journal ArticleDOI
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function
Cristian Pattaro,Alexander Teumer,Mathias Gorski,Audrey Y. Chu,Man Li,Vladan Mijatovic,Maija K. Garnaas,Adrienne Tin,Rossella Sorice,Yong Li,Daniel Taliun,Matthias Olden,Meredith C. Foster,Qiong Yang,Ming-Huei Chen,Tune H. Pers,Tune H. Pers,Andrew D. Johnson,Yi-An Ko,Christian Fuchsberger,Bamidele O. Tayo,Mike A. Nalls,Mary F. Feitosa,Aaron Isaacs,Abbas Dehghan,Pio D'Adamo,Adebowale Adeyemo,Aida Karina Dieffenbach,Alan B. Zonderman,Ilja M. Nolte,Peter J. van der Most,Alan F. Wright,Alan R. Shuldiner,Alan R. Shuldiner,Alanna C. Morrison,Albert Hofman,Albert V. Smith,Albert W. Dreisbach,Andre Franke,André G. Uitterlinden,Andres Metspalu,Anke Tönjes,Antonio Lupo,Antonietta Robino,Åsa Johansson,Ayse Demirkan,Barbara Kollerits,Barry I. Freedman,Belen Ponte,Ben A. Oostra,Bernhard Paulweber,Bernhard K. Krämer,Braxton D. Mitchell,Braxton D. Mitchell,Brendan M. Buckley,Carmen A. Peralta,Caroline Hayward,Catherine Helmer,Catherine Helmer,Charles N. Rotimi,Christian M. Shaffer,Christian Müller,Cinzia Sala,Cornelia M. van Duijn,Aude Saint-Pierre,Daniel Ackermann,Daniel Shriner,Daniela Ruggiero,Daniela Toniolo,Yingchang Lu,Daniele Cusi,Darina Czamara,David Ellinghaus,David S. Siscovick,Douglas M. Ruderfer,Christian Gieger,Harald Grallert,Elena Rochtchina,Elizabeth J. Atkinson,Elizabeth G. Holliday,Eric Boerwinkle,Erika Salvi,Erwin P. Bottinger,Federico Murgia,Fernando Rivadeneira,Florian Ernst,Florian Kronenberg,Frank B. Hu,Gerjan Navis,Gary C. Curhan,G. Ehret,Georg Homuth,Stefan Coassin,Gian Andri Thun,Gian Andri Thun,Giorgio Pistis,Giovanni Gambaro,Giovanni Malerba,Grant W. Montgomery,Gudny Eiriksdottir,Gunnar Jacobs,Guo Li,H.-Erich Wichmann,Harry Campbell,Helena Schmidt,Henri Wallaschofski,Henry Völzke,Hermann Brenner,Heyo K. Kroemer,Holly Kramer,Honghuang Lin,I. Mateo Leach,Ian Ford,Idris Guessous,Idris Guessous,Idris Guessous,Igor Rudan,Inga Prokopenko,Ingrid B. Borecki,Iris M. Heid,Ivana Kolcic,Ivana Persico,J. Wouter Jukema,James F. Wilson,Janine F. Felix,Jasmin Divers,Jean-Charles Lambert,Jeanette M. Stafford,Jean-Michel Gaspoz,Jennifer A. Smith,Jessica D. Faul,Jie Jin Wang,Jingzhong Ding,Joel N. Hirschhorn,Joel N. Hirschhorn,John Attia,John Attia,John Whitfield,John Chalmers,J. Viikari,Josef Coresh,Joshua C. Denny,Juha Karjalainen,Jyotika K. Fernandes,Karlhans Endlich,Katja Butterbach,Keith L. Keene,Kurt Lohman,Laura Portas,Lenore J. Launer,Leo-Pekka Lyytikäinen,Loic Yengo,Loic Yengo,Loic Yengo,Lude Franke,Luigi Ferrucci,Lynda M. Rose,Lyudmyla Kedenko,Madhumathi Rao,Maksim Struchalin,Marcus E. Kleber,Margherita Cavalieri,Margot Haun,Marilyn C. Cornelis,Marina Ciullo,Mario Pirastu,Mariza de Andrade,Mark McEvoy,Mark Woodward,Martin Adam,Martin Adam,Massimiliano Cocca,Matthias Nauck,Medea Imboden,Medea Imboden,Melanie Waldenberger,Menno Pruijm,Marie Metzger,Michael Stumvoll,Michele K. Evans,Michèle M. Sale,Mika Kähönen,Mladen Boban,Murielle Bochud,Myriam Rheinberger,Niek Verweij,Nabila Bouatia-Naji,Nabila Bouatia-Naji,Nicholas G. Martin,Nicholas G. Martin,Nicholas D. Hastie,Nicole Probst-Hensch,Nicole Probst-Hensch,Nicole Soranzo,Olivier Devuyst,Olli T. Raitakari,Omri Gottesman,Oscar H. Franco,Ozren Polasek,Paolo Gasparini,Patricia B. Munroe,Paul M. Ridker,Paul Mitchell,Paul Muntner,Christa Meisinger,Johannes H. Smit,Gonçalo R. Abecasis,Linda S. Adair,Myriam Alexander,David Altshuler,Najaf Amin,Dan E. Arking,Pankaj Arora,Yurii S. Aulchenko,Stephan J. L. Bakker,Stefania Bandinelli,Inês Barroso,Jacques S. Beckmann,John Beilby,Richard N. Bergman,Sven Bergmann,Joshua C. Bis,Michael Boehnke,Lori L. Bonnycastle,Stefan R. Bornstein,Michiel L. Bots,Jennifer L. Bragg-Gresham,Stefan Martin Brand,Eva Brand,Peter S. Braund,Morris J. Brown,Paul Burton,Juan P. Casas,Mark J. Caulfield,Aravinda Chakravarti,John C. Chambers,Giriraj R. Chandak,Yen Pei C. Chang,Fadi J. Charchar,Nish Chaturvedi,Yoon Shin Cho,Robert Clarke,Francis S. Collins,Rory Collins,John M. C. Connell,Jackie A. Cooper,Mark E. Cooper,Richard S. Cooper,Anna Maria Corsi,Marcus Dörr,Santosh Dahgam,John Danesh,George Davey Smith,Ian N. M. Day,Panos Deloukas,Matthew Denniff,Anna F. Dominiczak,Yanbin Dong,Ayo P. Doumatey,Paul Elliott,Roberto Elosua,Jeanette Erdmann,Susana Eyheramendy,Martin Farrall,Cristiano Fava,Terrence Forrester,F. Gerald R. Fowkes,Ervin R. Fox,Timothy M. Frayling,Pilar Galan,Santhi K. Ganesh,Melissa Garcia,Tom R. Gaunt,Nicole L. Glazer,Min Jin Go,Anuj Goel,Jürgen Grässler,Diederick E. Grobbee,Leif Groop,Simonetta Guarrera,Xiuqing Guo,David Hadley,Anders Hamsten,Bok Ghee Han,Rebecca Hardy,Anna-Liisa Hartikainen,Simon Heath,Susan R. Heckbert,Bo Hedblad,Serge Hercberg,Dena G. Hernandez,Andrew A. Hicks,Gina Hilton,Aroon D. Hingorani,Judith A. Hoffman Bolton,Jemma C. Hopewell,Philip Howard,Steve E. Humphries,Steven C. Hunt,Kristian Hveem,M. Arfan Ikram,Muhammad Islam,Naoharu Iwai,Marjo-Riitta Järvelin,Anne U. Jackson,Tazeen H. Jafar,C. S. Janipalli,Toby Johnson,Sekar Kathiresan,Kay-Tee Khaw,Hyung Lae Kim,Sanjay Kinra,Yoshikuni Kita,Mika Kivimäki,Jaspal S. Kooner,M. J.Kranthi Kumar,Diana Kuh,Smita R. Kulkarni,Meena Kumari,Johanna Kuusisto,Tatiana Kuznetsova,Markku Laakso,Maris Laan,Jaana Laitinen,Edward G. Lakatta,Carl D. Langefeld,Martin G. Larson,Mark Lathrop,Debbie A Lawlor,Robert W. Lawrence,Jong-Young Lee,Nanette R. Lee,Daniel Levy,Yali Li,Will Longstreth,Jian'an Luan,Gavin Lucas,Barbara Ludwig,Massimo Mangino,K. Radha Mani,Michael Marmot,Francesco U.S. Mattace-Raso,Giuseppe Matullo,Wendy L. McArdle,Colin A. McKenzie,Thomas Meitinger,Olle Melander,Pierre Meneton,James F. Meschia,Tetsuro Miki,Yuri Milaneschi,Karen L. Mohlke,Vincent Mooser,Mario A. Morken,Richard W Morris,Thomas H. Mosley,Samer S. Najjar,Narisu Narisu,Christopher Newton-Cheh,Khanh-Dung H. Nguyen,Peter M. Nilsson,Fredrik Nyberg,Christopher J. O'Donnell,Toshio Ogihara,Takayoshi Ohkubo,Tomonori Okamura,Rick Twee-Hee Ong,Halit Ongen,N. Charlotte Onland-Moret,Paul F. O'Reilly,Elin Org,Marco Orrù,Walter Palmas,Jutta Palmen,Lyle J. Palmer,Nicholette D. Palmer,Alex Parker,John F. Peden,Leena Peltonen,Markus Perola,Vasyl Pihur,Carl G. P. Platou,Andrew S. Plump,Dorairajan Prabhakaran,Bruce M. Psaty,Leslie J. Raffel,Dabeeru C. Rao,Asif Rasheed,Fulvio Ricceri,Kenneth Rice,Annika Rosengren,Jerome I. Rotter,Megan E. Rudock,Siim Sõber,Tunde Salako,Danish Saleheen,Veikko Salomaa,Nilesh J. Samani,Steven M. Schwartz,Peter Schwarz,Laura J. Scott,James Scott,Angelo Scuteri,Joban Sehmi,Mark Seielstad,Sudha Seshadri,Pankaj Sharma,Sue Shaw-Hawkins,Gang Shi,Nick Shrine,Eric J.G. Sijbrands,Xueling Sim,Andrew B. Singleton,Marketa Sjögren,Nicholas L. Smith,María Soler Artigas,Tim D. Spector,Jan A. Staessen,Alena Stančáková,Nanette I. Steinle,David P. Strachan,Heather M. Stringham,Yan V. Sun,Amy J. Swift,Yasuharu Tabara,E. Shyong Tai,Philippa J. Talmud,Andrew M. Taylor,Janoš Terzić,Dag S. Thelle,Martin D. Tobin,Maciej Tomaszewski,Vikal Tripathy,Jaakko Tuomilehto,Ioanna Tzoulaki,Manuela Uda,Hirotsugu Ueshima,Cuno S. P. M. Uiterwaal,Satoshi Umemura,Pim van der Harst,Yvonne T. van der Schouw,Wiek H. van Gilst,Erkki Vartiainen,Ramachandran S. Vasan,Gudrun Veldre,Germaine C. Verwoert,Margus Viigimaa,D. G. Vinay,Paolo Vineis,Benjamin F. Voight,Peter Vollenweider,Lynne E. Wagenknecht,Louise V. Wain,Xiaoling Wang,Thomas J. Wang,Nicholas J. Wareham,Hugh Watkins,Alan B. Weder,Peter H. Whincup,Kerri L. Wiggins,Jacqueline C.M. Witteman,Andrew Wong,Ying Wu,Chittaranjan S. Yajnik,Jie Yao,J. H. Young,Diana Zelenika,Guangju Zhai,Weihua Zhang,Feng Zhang,Jing Hua Zhao,Haidong Zhu,Xiaofeng Zhu,Paavo Zitting,Ewa Zukowska-Szczechowska,Yukinori Okada,Jer-Yuarn Wu,Jer-Yuarn Wu,Dongfeng Gu,Fumihiko Takeuchi,Atsushi Takahashi,Shiro Maeda,Tatsuhiko Tsunoda,Peng Chen,Su Chi Lim,Su Chi Lim,Tien Yin Wong,Tien Yin Wong,Tien Yin Wong,Jianjun Liu,Terri L. Young,Tin Aung,Tin Aung,Yik Ying Teo,Yik Ying Teo,Young-Jin Kim,Daehee Kang,Chien-Hsiun Chen,Chien-Hsiun Chen,Fuu Jen Tsai,Li Ching Chang,S. J.Cathy Fann,Hao Mei,James E. Hixson,Shufeng Chen,Tomohiro Katsuya,Masato Isono,Eva Albrecht,Kazuhiko Yamamoto,Michiaki Kubo,Yusuke Nakamura,Naoyuki Kamatani,Norihiro Kato,Jiang He,Yuan-Tsong Chen,Toshihiro Tanaka,Muredach P. Reilly,Heribert Schunkert,Heribert Schunkert,Themistocles L. Assimes,Alistair S. Hall,Christian Hengstenberg,Inke R. König,Reijo Laaksonen,Ruth McPherson,John R. Thompson,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Andreas Ziegler,Devin Absher,Li Chen,L. Adrienne Cupples,L. Adrienne Cupples,Eran Halperin,Eran Halperin,Mingyao Li,Kiran Musunuru,Kiran Musunuru,Michael Preuss,Arne Schillert,Gudmar Thorleifsson,George A. Wells,Hilma Holm,Robert Roberts,Alexandre F.R. Stewart,Stephen P. Fortmann,Alan S. Go,Mark A. Hlatky,Carlos Iribarren,Joshua W. Knowles,Richard M. Myers,Thomas Quertermous,S. Sidney,Neil Risch,Hua Tang,Stefan Blankenberg,Renate B. Schnabel,C. Sinning,Karl J. Lackner,Laurence Tiret,Viviane Nicaud,François Cambien,Christoph Bickel,Hans J. Rupprecht,Claire Perret,Carole Proust,Thomas Münzel,Maja Barbalić,Ida Yii Der Chen,Serkalem Demissie-Banjaw,Serkalem Demissie-Banjaw,Aaron R. Folsom,Thomas Lumley,Kristin D. Marciante,Kent D. Taylor,Kelly A. Volcik,Solveig Gretarsdottir,Jeffrey R. Gulcher,Augustine Kong,Kari Stefansson,Kari Stefansson,Gudmundur Thorgeirsson,Karl Andersen,Marcus Fischer,Anika Grosshennig,Patrick Linsel-Nitschke,Klaus Stark,Stefan Schreiber,Zouhair Aherrahrou,Petra Bruse,Angela Doering,Norman Klopp,Patrick Diemert,Christina Loley,Anja Medack,Janja Nahrstedt,Annette Peters,Arnika Kathleen Wagner,Christina Willenborg,Bernhard O. Böhm,Harald Dobnig,Tanja B. Grammer,Michael M. Hoffmann,Andreas Meinitzer,Bernhard R. Winkelmann,Stefan Pilz,Wilfried Renner,Hubert Scharnagl,Tatjana Stojakovic,Andreas Tomaschitz,Karl Winkler,Candace Guiducci,Noël P. Burtt,Stacey Gabriel,Sonny Dandona,Olga Jarinova,Liming Qu,Robert L. Wilensky,William H. Matthai,Hakon Hakonarson,Joe Devaney,Mary Susan Burnett,Augusto D. Pichard,Kenneth M. Kent,Lowell F. Satler,Joseph M. Lindsay,Ron Waksman,Christopher W. Knouff,Dawn M. Waterworth,M Walker,Stephen E. Epstein,Daniel J. Rader,Christopher P. Nelson,Benjamin J. Wright,Anthony J. Balmforth,Stephen G. Ball,Laura R. Loehr,Laura R. Loehr,Wayne D. Rosamond,Emelia J. Benjamin,Talin Haritunians,David Couper,Joanne M. Murabito,Ying A. Wang,Bruno H. Stricker,Patricia P. Chang,James T. Willerson,James T. Willerson,Stephan B. Felix,Norbert Watzinger,Jayashri Aragam,Robert Zweiker,Lars Lind,Richard J. Rodeheffer,Karin Halina Greiser,Jaap W. Deckers,Jan Stritzke,Erik Ingelsson,Iftikhar J. Kullo,Johannes Haerting,Thorsten Reffelmann,Margaret M. Redfield,Karl Werdan,Gary F. Mitchell,Donna K. Arnett,John S. Gottdiener,Maria Blettner,Nele Friedrich,Peter Kovacs,Philipp S. Wild,Philippe Froguel,Philippe Froguel,Philippe Froguel,Rainer Rettig,Reedik Mägi,Reiner Biffar,Reinhold Schmidt,Rita P.S. Middelberg,Robert J. Carroll,Brenda W.J.H. Penninx,Rodney J. Scott,Ronit Katz,Sanaz Sedaghat,Sarah H. Wild,Sharon L.R. Kardia,Sheila Ulivi,Shih-Jen Hwang,Stefan Enroth,Stefan Kloiber,Stella Trompet,Bénédicte Stengel,Stephen Hancock,Stephen Turner,Sylvia E. Rosas,Sylvia Stracke,Sylvia Stracke,Tamara B. Harris,Tanja Zeller,Tatijana Zemunik,Terho Lehtimäki,Thomas Illig,Thor Aspelund,Tiit Nikopensius,Tõnu Esko,Tõnu Esko,Toshiko Tanaka,Ulf Gyllensten,Uwe Völker,Valur Emilsson,Veronique Vitart,Ville Aalto,Vilmundur Gudnason,Vincent Chouraki,Wei-Min Chen,Wilmar Igl,Winfried März,Wolfgang Koenig,Wolfgang Lieb,Ruth J. F. Loos,Yongmei Liu,Harold Snieder,Peter P. Pramstaller,Afshin Parsa,Jeffrey R. O'Connell,Katalin Susztak,Pavel Hamet,Johanne Tremblay,Ian H. de Boer,Carsten A. Böger,Wolfram Goessling,Daniel I. Chasman,Anna Köttgen,Anna Köttgen,W. H. Linda Kao,Caroline S. Fox,Caroline S. Fox +735 more
TL;DR: A meta-analysis of genome-wide association studies for estimated glomerular filtration rate suggests that genetic determinants of eGFR are mediated largely through direct effects within the kidney and highlight important cell types and biological pathways.
Journal ArticleDOI
The Predictive Value of Different Measures of Obesity for Incident Cardiovascular Events and Mortality
Harald Jörn Schneider,Nele Friedrich,Jens Klotsche,Lars Pieper,Matthias Nauck,Ulrich John,Marcus Dörr,Stephan B. Felix,Hendrik Lehnert,David Pittrow,Sigmund Silber,Henry Völzke,Günter K. Stalla,Henri Wallaschofski,Hans-Ulrich Wittchen +14 more
TL;DR: WHtR represents the best predictor of cardiovascular risk and mortality, followed by WC and WHR, and the results discourage the use of the BMI.
Journal ArticleDOI
A genome-wide association study of metabolic traits in human urine
Karsten Suhre,Henri Wallaschofski,Johannes Raffler,Nele Friedrich,Robin Haring,Kathrin Michael,Christina Wasner,Alexander Krebs,Florian Kronenberg,David C. Chang,Christa Meisinger,H-Erich Wichmann,Wolfgang Hoffmann,Henry Völzke,Uwe Völker,Alexander Teumer,Reiner Biffar,Thomas Kocher,Stephan B. Felix,Thomas Illig,Heyo K. Kroemer,Christian Gieger,Werner Römisch-Margl,Matthias Nauck +23 more
TL;DR: A genome-wide association study of metabolic traits in human urine, designed to investigate the detoxification capacity of the human body, identifies rs37369 in AGXT2 as the genetic basis of hyper-β-aminoisobutyric aciduria and identifies five loci with joint P values of association.