Artur M. S. Silva

TL;DR: In this review, a thorough compilation of the most promising antileishmanial acridine and xanthene derivatives is performed from both natural and synthetic origins to highlight the relevance of nitrogen- and oxygen-containing tricyclic heterocycles, particularly acridines and xanine derivatives, for the development of treatments against leishmaniasis.

TL;DR: The 3-alkyl-3-4-5,7-tetramethoxyflavones were demethylated with boron tribromide.

TL;DR: The synthesis of substituted 2‐hydroxybenzophenones through 1,4‐conjugate addition/intramolecular cycloaddition/dehydration of nitromethane on key intermediate chromones is reported, which exhibited good cytotoxic effects against the three cancer cell lines.

TL;DR: In this article, Piere et al. isolated four compounds from the stem bark of Polyalthia jucunda, including 4-hydroxy-4, 7-dimethyl-α.-tetralone (1), 4,5-dihydroblumenol A (2), N.-trans-feruloyltyramine (3), and 24-methylenelanosta-7, 9(11)-dien-3-β., 15α.-diol (4) were evaluated for their effects on growth.

TL;DR: In this paper, a new and efficient route for the synthesis of (E)-N-methyl-3-styryl-4-quinolones is described, which involves the Heck reaction of N-methyl, 3-iodo-4 -quinolone, which is obtained by consecutive 3iodination and NH-methylation of the unsubstituted 4-quinoline with styrene derivatives.