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Nora G. Singer
Researcher at MetroHealth
Publications - 29
Citations - 2372
Nora G. Singer is an academic researcher from MetroHealth. The author has contributed to research in topics: T cell & Antigen. The author has an hindex of 16, co-authored 29 publications receiving 2078 citations. Previous affiliations of Nora G. Singer include University of Michigan & Case Western Reserve University.
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Journal ArticleDOI
Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2010
Daniel E. Furst,E.C. Keystone,J. Braun,F. C. Breedveld,G.-R. Burmester,F De Benedetti,Thomas Dörner,Paul Emery,Roy Fleischmann,Allan Gibofsky,Joachim R. Kalden,A. Kavanaugh,Bruce Kirkham,Philip J. Mease,J. Sieper,Nora G. Singer,Josef S Smolen,P.L.C.M. van Riel,Michael H. Weisman,Kevin L. Winthrop +19 more
TL;DR: The consensus statement is annotated to document the credibility of the data supporting it as much as possible and the number of possible references has become so large that reviews are sometimes included; if they contain category A references, they will be referred to as category A evidence.
Journal ArticleDOI
Early-Onset Stroke and Vasculopathy Associated with Mutations in ADA2
Qing Zhou,Dan Yang,Amanda K. Ombrello,Andrey Zavialov,Camilo Toro,Anton V. Zavialov,Deborah L. Stone,Jae Jin Chae,Sergio D. Rosenzweig,Kevin Bishop,Karyl S. Barron,Hye Sun Kuehn,Patrycja Hoffmann,Alejandra Negro,Wanxia L. Tsai,Edward W. Cowen,Wuhong Pei,Joshua D. Milner,Christopher Silvin,Theo Heller,David T. Chin,Nicholas J. Patronas,John S. Barber,Chyi-Chia Richard Lee,Geryl Wood,Alexander Ling,Susan J. Kelly,David E. Kleiner,James C. Mullikin,Nancy J. Ganson,Heidi H. Kong,Sophie Hambleton,Fabio Candotti,Martha Quezado,Katherine R. Calvo,Hawwa Alao,Beverly K. Barham,Anne Jones,James F. Meschia,Bradford B. Worrall,Scott E. Kasner,Stephen S. Rich,Raphaela Goldbach-Mansky,Mario Abinun,Elizabeth Chalom,Alisa Gotte,Marilynn Punaro,Virginia Pascual,James W. Verbsky,Troy R. Torgerson,Nora G. Singer,Timothy R. Gershon,Seza Ozen,Omer Karadag,Thomas A. Fleisher,Elaine F. Remmers,Shawn M. Burgess,Susan Moir,Massimo Gadina,Raman Sood,Michael S. Hershfield,Manfred Boehm,Daniel L. Kastner,Ivona Aksentijevich +63 more
TL;DR: Loss-of-function mutations in CECR1 were associated with a spectrum of vascular and inflammatory phenotypes, ranging from early-onset recurrent stroke to systemic vasculopathy or vasculitis, and were prevented by coinjection with nonmutated (but not with mutated) human C ECR1.
Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2012
Daniel E. Furst,Edward C. Keystone,A.K. So,J. Braun,Ferdinand C. Breedveld,G.-R. Burmester,F De Benedetti,Thomas Dörner,Paul Emery,Roy Fleischmann,Allan Gibofsky,J. R. Kalden,A. Kavanaugh,Bruce Kirkham,Philip J. Mease,Andrea Rubbert-Roth,J. Sieper,Nora G. Singer,Josef S. Smolen,P.L.C.M. van Riel,Michael H. Weisman,Kevin L. Winthrop +21 more
TL;DR: Attainment of inactive disease status following initiation of TNF-alpha inhibitor therapy for juvenile idiopathic arthritis: enthesitis-related arthritis predicts persistent active disease.
Journal ArticleDOI
Classification, presentation, and initial treatment of Wegener's granulomatosis in childhood
David A. Cabral,América G. Uribe,Susanne M. Benseler,Kathleen M. O'Neil,Philip J. Hashkes,Gloria C. Higgins,Andrew Zeft,Daniel J. Lovell,Daniel J. Kingsbury,Anne M. Stevens,Deborah McCurdy,Peter Chira,Leslie Abramson,Thaschawee Arkachaisri,Sarah Campillo,Anne Eberhard,Aimee O. Hersh,Adam M. Huber,Susan Kim,Marisa S. Klein-Gitelman,Deborah M. Levy,Suzanne C. Li,Thomas G. Mason,Esi Morgan DeWitt,Eyal Muscal,Lorien Nassi,Andreas Reiff,Kenneth N. Schikler,Nora G. Singer,Dawn M. Wahezi,Amy Woodward,Victor Espinosa,Jaime Guzman,Kristin Houghton,Peter N. Malleson,Ross E. Petty,Lori B. Tucker,Stuart E. Turvey,Elizabeth B. Brooks,Mary Lesko,Fatma Dedeoglu,Robert C. Fuhlbrigge,Melissa M. Hazen,Mary Beth F. Son,Robert P. Sundel,Diane E. Brown,Bracha Shaham,Ana Cabrera,Norman T. Ilowite,Raphael Hirsh,Daniel Kietz,Paul Rosen,Margalit Rosenkrank,Kathryn S. Torok,Lauren M. Pachman,Aisha Ali,Hermine I. Brunner,Thomas A. Griffin,A. Grom,Anne Johnson,Steven J. Spalding,Deborah Bork,Stacy P. Ardoin,Egla Rabinovich,Laura E. Schanberg,Rhonda Wilder,Bianca A. Lang,Suzanne E. Ramsey,Elizabeth Stringer,Aleasha Warner,Kathleen A. Haines,Yukiko Kimura,J Weiss,Imelda Balboni,Reuven Bromberg,Michal Cidon,Jennifer Frankovich,Dana Gerstbacher,Joyce J. Hsu,Tzielan Lee,Jane L. Park,Christy Sandborg,Steven J. Song,Ann M. Reed,Gaëlle Chédeville,Ciarán M. Duffy,Karen Watanabe Duffy,Rosie Scuccimarri,Michele Gibbon,Andrew H. Eichenfield,Lisa Imundo,Candido Batres,Suzanne L. Bowyer,Susan H. Ballinger,Thomas Klausmeier,Andrea Hudgins,Helen Emery,Kristin Hayward,Christi J. Inman,Sarah Ringold,Elizabeth A. Shaw,Troy R. Torgerson,Jennifer Turner,Carol A. Wallace,Jennifer Wargula,Sarah Halford,Barry L. Myones,Marilynn Punaro,Virginia Pascual,Emily von Scheven,Adrienne Michels,Michael Henrickson,James N. Jarvis,John Bonsack,S Prahalad +114 more
TL;DR: The EULAR/PRES criteria minimally improved diagnostic sensitivity and specificity for Wegener's granulomatosis among a narrow spectrum of children with AAVs.
Journal ArticleDOI
Randomized, Double‐Blind, Placebo‐Controlled Trial of the Efficacy and Safety of Rilonacept in the Treatment of Systemic Juvenile Idiopathic Arthritis
Norman T. Ilowite,Kristi Prather,Yuliya Lokhnygina,Laura E. Schanberg,Melissa E. Elder,Diana Milojevic,James W. Verbsky,Steven J. Spalding,Yukiko Kimura,Lisa Imundo,Marilynn Punaro,David D. Sherry,Stacey E. Tarvin,Lawrence S. Zemel,James D Birmingham,Beth S. Gottlieb,Michael L. Miller,Kathleen M. O'Neil,Natasha M. Ruth,Carol A. Wallace,Nora G. Singer,Christy Sandborg +21 more
TL;DR: To assess the efficacy and safety of rilonacept, an interleukin‐1 inhibitor, in a randomized, double‐blind, placebo‐controlled trial.