Javier Quilez

TL;DR: The whole-genome analysis of a cartilaginous fish, the elephant shark (Callorhinchus milii), finds that the C. milii genome is the slowest evolving of all known vertebrates, and features extensive synteny conservation with tetrapod genomes, making it a good model for comparative analyses of gnathostome genomes.

TL;DR: The assembly and analysis of a northern white-cheeked gibbon genome is presented and the propensity for a gibbon-specific retrotransposon (LAVA) to insert into chromosome segregation genes and alter transcription by providing a premature termination site is described, suggesting a possible molecular mechanism for the genome plasticity of the gibbon lineage.

TL;DR: An approximately 7,000-year-old Mesolithic skeleton discovered at the La Braña-Arintero site in León, Spain, is sequenceed to retrieve a complete pre-agricultural European human genome, providing evidence that a significant number of derived, putatively adaptive variants associated with pathogen resistance in modern Europeans were already present in this hunter-gatherer.

TL;DR: It is concluded that 3D genome reorganization generally precedes gene expression changes and that removal of locus-specific topological barriers explains why pluripotency genes are activated sequentially during reprogramming.

TL;DR: Insight is provided into how the process of domestication altered the ancestral wildcat genome and build a resource for future disease mapping and phylogenomic studies across all members of the Felidae.