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Cecile Colpaert
Researcher at University of Antwerp
Publications - 98
Citations - 5385
Cecile Colpaert is an academic researcher from University of Antwerp. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 35, co-authored 94 publications receiving 4603 citations. Previous affiliations of Cecile Colpaert include Katholieke Universiteit Leuven.
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Journal ArticleDOI
Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group Part 2 TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non–Small Cell Lung Carcinoma and Mesothelioma, Endometrial and Ovarian Carcinomas, Squamous Cell Carcinoma of the Head and Neck, Genitourinary Carcinomas, and Primary Brain Tumors
Shona Hendry,Roberto Salgado,Thomas Gevaert,Prudence A. Russell,Prudence A. Russell,Thomas John,Thomas John,Bibhusal Thapa,Michael Christie,Koen Van de Vijver,Monica V. Estrada,Paula I. Gonzalez-Ericsson,Melinda E. Sanders,Benjamin Solomon,Cinzia Solinas,Gert Van den Eynden,Yves Allory,Yves Allory,Matthias Preusser,Johannes A. Hainfellner,Giancarlo Pruneri,Andrea Vingiani,Sandra Demaria,Fraser Symmans,Paolo Nuciforo,Laura Comerma,E. A. Thompson,Sunil R. Lakhani,Sunil R. Lakhani,Seong Rim Kim,Stuart J. Schnitt,Cecile Colpaert,Christos Sotiriou,Stefan J. Scherer,Michail Ignatiadis,Sunil S. Badve,Robert H. Pierce,Giuseppe Viale,Nicolas Sirtaine,Frédérique Penault-Llorca,Tomohagu Sugie,Susan Fineberg,Soonmyung Paik,Ashok Srinivasan,Andrea L. Richardson,Yihong Wang,Yihong Wang,Ewa Chmielik,Jane E. Brock,Douglas B. Johnson,Justin M. Balko,Stephan Wienert,Veerle Bossuyt,Stefan Michiels,Nils Ternès,Nicole Burchardi,Stephen J Luen,Stephen J Luen,Peter Savas,Peter Savas,Frederick Klauschen,Peter H. Watson,Peter H. Watson,Brad H. Nelson,Brad H. Nelson,Carmen Criscitiello,Sandra A O'Toole,Denis Larsimont,Roland de Wind,Giuseppe Curigliano,Fabrice Andre,Magali Lacroix-Triki,Mark van de Vijver,Federico Rojo,Giuseppe Floris,Shahinaz Bedri,Joseph A. Sparano,David L. Rimm,Torsten O. Nielsen,Zuzana Kos,Stephen M. Hewitt,Baljit Singh,Gelareh Farshid,Gelareh Farshid,Sibylle Loibl,Kimberly H. Allison,Nadine Tung,Sylvia Adams,Karen Willard-Gallo,Hugo M. Horlings,Leena Gandhi,Leena Gandhi,Andre L. Moreira,Fred R. Hirsch,Maria Vittoria Dieci,Maria Urbanowicz,Iva Brcic,Konstanty Korski,Fabien Gaire,Hartmut Koeppen,Amy C. Y. Lo,Amy C. Y. Lo,Jennifer M. Giltnane,Marlon Rebelatto,Keith Steele,Jiping Zha,Kenneth Emancipator,Jonathan Juco,Carsten Denkert,Jorge S. Reis-Filho,Sherene Loi,Stephen B. Fox +111 more
TL;DR: Standardization of TIL assessment will help clinicians, researchers and pathologists to conclusively evaluate the utility of this simple biomarker in the current era of immunotherapy.
Journal ArticleDOI
Assessing Tumor-infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immunooncology Biomarkers Working Group: Part 1: Assessing the Host Immune Response, TILs in Invasive Breast Carcinoma and Ductal Carcinoma in Situ, Metastatic Tumor Deposits and Areas for Further Research
Shona Hendry,Roberto Salgado,Thomas Gevaert,Prudence A. Russell,Prudence A. Russell,Thomas John,Thomas John,Bibhusal Thapa,Michael Christie,Koen Van de Vijver,Monica V. Estrada,Paula I. Gonzalez-Ericsson,Melinda E. Sanders,Benjamin sss Solomon,Cinzia Solinas,Gert Van den Eynden,Yves Allory,Yves Allory,Matthias Preusser,Johannes A. Hainfellner,Giancarlo Pruneri,Andrea Vingiani,Sandra Demaria,Fraser Symmans,Paolo Nuciforo,Laura Comerma,E. A. Thompson,Sunil R. Lakhani,Sunil R. Lakhani,Seong-Rim Kim,Stuart J. Schnitt,Cecile Colpaert,Christos Sotiriou,Stefan J. Scherer,Michail Ignatiadis,Sunil Badve,Robert H. Pierce,Giuseppe Viale,Nicolas Sirtaine,Frédérique Penault-Llorca,Tomohagu Sugie,Susan Fineberg,Soonmyung Paik,Ashok Srinivasan,Andrea L. Richardson,Yihong Wang,Yihong Wang,Ewa Chmielik,Jane E. Brock,Douglas B. Johnson,Justin M. Balko,Stephan Wienert,Veerle Bossuyt,Stefan Michiels,Nils Ternès,Nicole Burchardi,Stephen J Luen,Stephen J Luen,Peter Savas,Peter Savas,Frederick Klauschen,Peter H. Watson,Brad H. Nelson,Carmen Criscitiello,Sandra A O'Toole,Denis Larsimont,Roland de Wind,Giuseppe Curigliano,Fabrice Andre,Magali Lacroix-Triki,Mark van de Vijver,Federico Rojo,Giuseppe Floris,Shahinaz Bedri,Joseph A. Sparano,David L. Rimm,Torsten O. Nielsen,Zuzana Kos,Stephen M. Hewitt,Baljit Singh,Gelareh Farshid,Sibylle Loibl,Kimberly H. Allison,Nadine Tung,Sylvia Adams,Karen Willard-Gallo,Hugo M. Horlings,Leena Gandhi,Leena Gandhi,Andre L. Moreira,Fred R. Hirsch,Maria Vittoria Dieci,Maria Urbanowicz,Iva Brcic,Konstanty Korski,Fabien Gaire,Hartmut Koeppen,Amy C. Y. Lo,Amy C. Y. Lo,Jennifer M. Giltnane,Marlon Rebelatto,Keith Steele,Jiping Zha,Kenneth Emancipator,Jonathan Juco,Carsten Denkert,Jorge S. Reis-Filho,Sherene Loi,Stephen B. Fox +108 more
TL;DR: In this paper, a standardized methodology to assess tumor-infiltrating lymphocytes (TILs) in solid tumors on hematoxylin and eosin sections, in both primary and metastatic settings, was proposed.
Journal ArticleDOI
Liver metastases from colorectal adenocarcinomas grow in three patterns with different angiogenesis and desmoplasia.
Peter B. Vermeulen,Cecile Colpaert,Roberto Salgado,Ruben Royers,Hilde Hellemans,Eva Van den Heuvel,G. Goovaerts,Luc Dirix,Eric Van Marck +8 more
TL;DR: It is demonstrated that liver metastases are a heterogeneous group, with different growth patterns which predict the fraction of immature blood vessels, the fractionof proliferating endothelial cells, and the fractions of apoptotic tumour cells.
Journal ArticleDOI
Increased Angiogenesis and Lymphangiogenesis in Inflammatory versus Noninflammatory Breast Cancer by Real-Time Reverse Transcriptase-PCR Gene Expression Quantification
Ilse Van der Auwera,Steven Van Laere,Gert Van den Eynden,Ina Benoy,Peter van Dam,Cecile Colpaert,Stephen B. Fox,Helen Turley,Adrian L. Harris,Eric Van Marck,Peter B. Vermeulen,Luc Dirix +11 more
TL;DR: Using real-time quantitative reverse transcriptase-PCR and immunohistochemistry, this study confirmed the intense angiogenic activity in inflammatory breast cancer and demonstrated the presence of active lymphangiogenesis in inflammatory breasts.
Journal ArticleDOI
Standardized evaluation of tumor-infiltrating lymphocytes in breast cancer: results of the ring studies of the international immuno-oncology biomarker working group.
Carsten Denkert,Stephan Wienert,Audrey Poterie,Sibylle Loibl,Jan Budczies,Sunil V. Badve,Zsuzsanna Bago-Horvath,Anita Bane,Shahinaz Bedri,Jane E. Brock,Ewa Chmielik,Matthias Christgen,Cecile Colpaert,Sandra Demaria,Gert Van den Eynden,Giuseppe Floris,Stephen B. Fox,Dongxia Gao,Barbara Ingold Heppner,S Rim Kim,Zuzana Kos,Hans Kreipe,Sunil R. Lakhani,Frédérique Penault-Llorca,Giancarlo Pruneri,Nina Radosevic-Robin,David L. Rimm,Stuart J. Schnitt,Bruno Valentin Sinn,Bruno Valentin Sinn,Peter Sinn,Nicolas Sirtaine,Sandra A O'Toole,Giuseppe Viale,Koen Van de Vijver,Roland de Wind,Gunter von Minckwitz,Frederick Klauschen,Michael Untch,Peter A. Fasching,Toralf Reimer,Karen Willard-Gallo,Stefan Michiels,Sherene Loi,Roberto Salgado +44 more
TL;DR: This large international standardization project shows that reproducible evaluation of TIL is feasible in breast cancer and opens the way for standardized reporting of tumor immunological parameters in clinical studies and diagnostic practice.