C
Charles DeCarli
Researcher at University of California, Davis
Publications - 721
Citations - 77364
Charles DeCarli is an academic researcher from University of California, Davis. The author has contributed to research in topics: Dementia & Hyperintensity. The author has an hindex of 125, co-authored 614 publications receiving 65820 citations. Previous affiliations of Charles DeCarli include University of Southern California & French Institute of Health and Medical Research.
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Journal ArticleDOI
Apolipoprotein ε4 is associated with lower brain volume in cognitively normal Chinese but not white older adults.
Jennifer S. Yokoyama,Allen K. L. Lee,Leonel T. Takada,Leonel T. Takada,Edgar Busovaca,Luke W. Bonham,Steven Z. Chao,Marian Tse,Jing He,Christopher G. Schwarz,Owen T. Carmichael,Brandy R. Matthews,Anna Karydas,Michael Weiner,Giovanni Coppola,Charles DeCarli,Bruce L. Miller,Howard J. Rosen +17 more
TL;DR: There is a differential effect of APOE ε4 on brain volume in Chinese versus white cognitively normal elderly adults, which represents a novel finding that, if verified in larger studies, has implications for how biological, environmental and/or lifestyle factors may modify APOEε4 effects on the brain in diverse populations.
Journal Article
Use of positron emission tomography for the evaluation of epilepsy.
TL;DR: The use of positron emission tomography as a tool for the localization of the pathologic brain region and as a predictor of surgical outcome in focal epilepsy is reviewed and compared with the sensitivity, specificity, and outcome predicted by other neuroimaging techniques.
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Plasma total‐tau as a biomarker of stroke risk in the community
Matthew P. Pase,Matthew P. Pase,Jayandra J. Himali,Hugo J. Aparicio,Jose R. Romero,Claudia L. Satizabal,Claudia L. Satizabal,Pauline Maillard,Charles DeCarli,Alexa S. Beiser,Sudha Seshadri +10 more
TL;DR: It is demonstrated that plasma total‐tau relates to the risk of stroke in a community sample in a prospective community‐based study.
Journal ArticleDOI
Relation of plasma β‐amyloid, clusterin, and tau with cerebral microbleeds: Framingham Heart Study
Jose R. Romero,Jose R. Romero,Serkalem Demissie,Alexa S. Beiser,Alexa S. Beiser,Jayandra J. Himali,Charles DeCarli,Daniel Levy,Sudha Seshadri +8 more
TL;DR: In this paper, the Framingham Heart Study participants with available CMB and biomarker measurements were included, using multivariable logistic regression analyses to identify biomarker levels (standardized for analyses) to CMB presence overall and stratified by brain topography.
Journal ArticleDOI
Magnetic resonance imaging-measured atrophy and its relationship to cognitive functioning in vascular dementia and Alzheimer's disease patients.
Mark W. Logue,Holly Posner,Richard C. Green,Margaret Moline,L. Adrienne Cupples,K. L. Lunetta,Heng Zou,Stephen W. Hurt,Lindsay A. Farrer,Charles DeCarli +9 more
TL;DR: MRI measures of vascular brain injury with neurodegenerative measures in clinically diagnosed subjects with either AD or VaD are compared and relationships among these measures within and between the two groups and their relationship to mental status are examined.