C
Charles DeCarli
Researcher at University of California, Davis
Publications - 721
Citations - 77364
Charles DeCarli is an academic researcher from University of California, Davis. The author has contributed to research in topics: Dementia & Hyperintensity. The author has an hindex of 125, co-authored 614 publications receiving 65820 citations. Previous affiliations of Charles DeCarli include University of Southern California & French Institute of Health and Medical Research.
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Cerebral small vessel disease genomics and its implications across the lifespan
Muralidharan Sargurupremraj,Hideaki Suzuki,Hideaki Suzuki,Xueqiu Jian,Xueqiu Jian,Chloé Sarnowski,Tavia E. Evans,Joshua C. Bis,Gudny Eiriksdottir,Saori Sakaue,Saori Sakaue,Natalie Terzikhan,Mohamad Habes,Mohamad Habes,Mohamad Habes,Wei Zhao,Nicola J. Armstrong,Edith Hofer,Lisa R. Yanek,Saskia P. Hagenaars,Saskia P. Hagenaars,Rajan B. Kumar,Erik B. van den Akker,Erik B. van den Akker,Erik B. van den Akker,Rebekah McWhirter,Rebekah McWhirter,Stella Trompet,Aniket Mishra,Yasaman Saba,Yasaman Saba,Claudia L. Satizabal,Claudia L. Satizabal,Gregory Beaudet,Laurent Petit,Ami Tsuchida,Laure Zago,Sabrina Schilling,Sigurdur Sigurdsson,Rebecca F. Gottesman,Cora E. Lewis,Neelum T. Aggarwal,Oscar L. Lopez,Jennifer A. Smith,Maria del C. Valdés Hernández,Jeroen van der Grond,Margaret J. Wright,Maria J. Knol,Marcus Dörr,Russell Thomson,Russell Thomson,Constance Bordes,Quentin Le Grand,Marie-Gabrielle Duperron,Albert V. Smith,David S. Knopman,Pamela J. Schreiner,Denis A. Evans,Jerome I. Rotter,Alexa S. Beiser,Susana Muñoz Maniega,Marian Beekman,Julian N. Trollor,David J. Stott,Meike W. Vernooij,Katharina Wittfeld,Wiro J. Niessen,Wiro J. Niessen,Aicha Soumare,Eric Boerwinkle,Stephen Sidney,Stephen T. Turner,Gail Davies,Gail Davies,Anbupalam Thalamuthu,Uwe Völker,Mark A. van Buchem,R. Nick Bryan,Josée Dupuis,Josée Dupuis,Mark E. Bastin,Mark E. Bastin,David Ames,David Ames,Alexander Teumer,Alexander Teumer,Philippe Amouyel,Philippe Amouyel,John B.J. Kwok,John B.J. Kwok,Robin Bülow,Ian J. Deary,Ian J. Deary,Peter R. Schofield,Peter R. Schofield,Henry Brodaty,Henry Brodaty,Jiyang Jiang,Yasuharu Tabara,Kazuya Setoh,Susumu Miyamoto,Kazumichi Yoshida,Manabu Nagata,Yoichiro Kamatani,Fumihiko Matsuda,Bruce M. Psaty,Bruce M. Psaty,David A. Bennett,Philip L. De Jager,Philip L. De Jager,Thomas H. Mosley,Perminder S. Sachdev,Reinhold Schmidt,Helen R. Warren,Helen R. Warren,Evangelos Evangelou,Evangelos Evangelou,David-Alexandre Trégouët,Mohammad Arfan Ikram,Wei Wen,Charles DeCarli,Velandai Srikanth,Velandai Srikanth,J. Wouter Jukema,Eline Slagboom,Sharon L.R. Kardia,Yukinori Okada,Bernard Mazoyer,Joanna M. Wardlaw,Paul A. Nyquist,Karen A. Mather,Karen A. Mather,Hans J. Grabe,Hans J. Grabe,Helena Schmidt,Cornelia M. van Duijn,Vilmundur Gudnason,William T. Longstreth,Lenore J. Launer,Mark Lathrop,Sudha Seshadri,Sudha Seshadri,Christophe Tzourio,Hieab H.H. Adams,Paul M. Matthews,Myriam Fornage,Stéphanie Debette,Stéphanie Debette +147 more
TL;DR: Insight is provided into BP-independent biological pathways underlying SVD and potential for genetic stratification of high-risk individuals and for genetically-informed prioritization of drug targets for prevention trials is suggested.
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Age and Education Effects on Relationships of Cognitive Test Scores With Brain Structure in Demographically Diverse Older Persons
TL;DR: Results suggest that demographic adjustment is beneficial when demographic variables are strongly related to test scores independent of measures of brain structure, but adjustment has negative consequences when effects of demographic characteristics are mediated by brain structure.
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Quantitative genetic modeling of regional brain volumes and cognitive performance in older male twins.
TL;DR: Bivariate genetic analysis revealed that while close to 60% of individual differences in neuropsychological performance were due to genetic influences, less than 50% of genetic effects were in common with those influencing brain volumes.
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Assessment of extent and role of tau in subcortical vascular cognitive impairment using 18F-AV1451 positron emission tomography imaging
Hee Jin Kim,Seongbeom Park,Hanna Cho,Young Kyoung Jang,Jin San Lee,Hyemin Jang,Yeshin Kim,Yeshin Kim,Ko Woon Kim,Ko Woon Kim,Young Hoon Ryu,Jae Yong Choi,Seung Hwan Moon,Michael W. Weiner,William J. Jagust,Gil D. Rabinovici,Charles DeCarli,Chul Hyoung Lyoo,Duk L. Na,Duk L. Na,Sang Won Seo +20 more
TL;DR: The findings suggest that in SVCI, both A&bgr; and CSVD were independently associated with increased tau accumulation, and tau burden played a pivotal role because it was the final common pathway for the cognitive impairment in patients with SVCi.
Journal ArticleDOI
Vascular factors in dementia: an overview
TL;DR: This review focuses on evolving data that support the hypothesis that cerebrovascular risk factors may cause asymptomatic brain injury, share genetic risk with Alzheimer's disease and possibly accelerate the Alzheimer's process.