C
Charles DeCarli
Researcher at University of California, Davis
Publications - 721
Citations - 77364
Charles DeCarli is an academic researcher from University of California, Davis. The author has contributed to research in topics: Dementia & Hyperintensity. The author has an hindex of 125, co-authored 614 publications receiving 65820 citations. Previous affiliations of Charles DeCarli include University of Southern California & French Institute of Health and Medical Research.
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Journal ArticleDOI
Reductions in parietal and temporal cerebral metabolic rates for glucose are not specific for Alzheimer's disease
Mark B. Schapiro,Pietro Pietrini,Cheryl L. Grady,Melvyn J. Ball,Charles DeCarli,Anand Kumar,Jeffrey Kaye,James V. Haxby +7 more
TL;DR: The results suggest that reductions of glucose metabolism in association neocortex in AD are not specific to the disease process, but may be related to the dementia state.
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Carotid Atherosclerosis and Cerebral Microbleeds: The Framingham Heart Study
Jose R. Romero,Sarah R. Preis,Alexa S. Beiser,Charles DeCarli,Ralph B. D'Agostino,Philip A. Wolf,Ramachandran S. Vasan,Joseph F. Polak,Sudha Seshadri +8 more
TL;DR: The apparent paradoxical association of carotid intima–media thickness progression with lower risk of CMB may reflect benefits of intensive vascular risk factor treatment among persons with higher cardiovascular risk and deserves further investigation.
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A multiancestral genome-wide exome array study of Alzheimer Disease, frontotemporal dementia, and progressive supranuclear palsy
Jason A. Chen,Qing Wang,Jeremy Davis-Turak,Yun Li,Anna Karydas,Sandy Chan Hsu,Renee L. Sears,Doxa Chatzopoulou,Alden Y. Huang,Kevin Wojta,Eric Klein,Jason Lee,Duane Beekly,Adam L. Boxer,Kelley Faber,Claudia M. Haase,Josh Miller,Wayne W. Poon,Ami Rosen,Howard J. Rosen,Anna Sapozhnikova,Jill S. Shapira,Arousiak Varpetian,Tatiana Foroud,Robert W. Levenson,Allan I. Levey,Walter A. Kukull,Mario F. Mendez,John M. Ringman,Helena C. Chui,Carl W. Cotman,Charles DeCarli,Bruce L. Miller,Daniel H. Geschwind,Giovanni Coppola +34 more
TL;DR: In this article, an exome array was applied to the multiancestral Genetic Investigation in Frontotemporal Dementia and Alzheimer's Disease (GIFT) Study cohort to determine the contribution of low-frequency coding variants to susceptibility to sporadic AD, PSP, and FTD.
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Cerebral magnetic resonance image segmentation using data fusion.
Jagath C. Rajapakse,Charles DeCarli,Alan C. McLaughlin,Jay N. Giedd,Amy L. Krain,Susan D. Hamburger,Judith L. Rapoport +6 more
TL;DR: This simple, reliable, and valid method can be employed in clinical research for quantification of gray and white matter and CSF volumes in MR head scans.
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Ethnoracial differences in brain structure change and cognitive change.
Brandon E. Gavett,Evan Fletcher,Danielle J Harvey,Sarah E Tomaszewski Farias,John M Olichney,Laurel A. Beckett,Charles DeCarli,Dan M Mungas +7 more
TL;DR: Ethnoracial group differences in associations of brain variables with cognitive decline appeared to suggest a greater influence of AD in Whites, and cognitive decline in African Americans and Hispanics was most uniquely attributable to global gray matter change and baseline WMH, respectively.