C
Charles DeCarli
Researcher at University of California, Davis
Publications - 721
Citations - 77364
Charles DeCarli is an academic researcher from University of California, Davis. The author has contributed to research in topics: Dementia & Hyperintensity. The author has an hindex of 125, co-authored 614 publications receiving 65820 citations. Previous affiliations of Charles DeCarli include University of Southern California & French Institute of Health and Medical Research.
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Journal ArticleDOI
The Impact of Amyloid-β or Tau on Cognitive Change in the Presence of Severe Cerebrovascular Disease.
Hyemin Jang,Hee Jin Kim,Yeong Sim Choe,Soo-Jong Kim,Seongbeom Park,Yeshin Kim,Ko Woon Kim,Chul Hyoung Lyoo,Hanna Cho,Young Hoon Ryu,Jae Yong Choi,Charles DeCarli,Duk L. Na,Sang Won Seo,Alzheimer’s Disease Neuroimaging Initiative +14 more
TL;DR: It is suggested that Aβ positivity or tau burden (particularly in the Braak III/IV or V/VI regions) and CSVD might synergistically affect cognitive decline.
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Non-Alcoholic Fatty Liver Disease, Liver Fibrosis, and Regional Amyloid-β and Tau Pathology in Middle-Aged Adults: The Framingham Study.
Galit Weinstein,Adrienne O’Donnell,Kendra Davis-Plourde,Shira Zelber-Sagi,Saptaparni Ghosh,Charles DeCarli,Emma G. Thibault,Reisa A. Sperling,Keith A. Johnson,Alexa S. Beiser,Sudha Seshadri +10 more
TL;DR: A possible association between liver fibrosis and early Alzheimer's disease pathology is suggested, independently of cardio-metabolic risk factors.
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Genome-wide scan in Hispanics highlights candidate loci for brain white matter hyperintensities.
Ashley Beecham,Chuanhui Dong,Clinton B. Wright,Nicole Dueker,Adam M. Brickman,Liyong Wang,Charles DeCarli,Charles DeCarli,Susan H. Blanton,Tatjana Rundek,Richard Mayeux,Ralph L. Sacco +11 more
TL;DR: This genome-wide association study of 2 community-based Hispanic cohorts revealed several novel WMH-associated genetic variants, and fine mapping is needed to pinpoint causal variants.
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Different associations of white matter lesions with depression and cognition
Jun-Young Lee,Jun-Young Lee,Philip S. Insel,R. Scott Mackin,Norbert Schuff,Norbert Schuff,Helena C. Chui,Charles DeCarli,Kee Hyung Park,Kee Hyung Park,Susanne G. Mueller,Michael Weiner,Michael Weiner +12 more
TL;DR: WML predicted frontal cortical volume, particularly in medial orbirtofrontal cortex, irrespective of age, gender, education, and group status, and this relationship was not mediated by regional frontal cortices.
Lower prevalence of silent brain infarcts in the physically active
TL;DR: In this paper, the authors examined the independent association between physical activity and subclinical cerebrovascular disease as measured by silent brain infarcts (SBI) and white matter hyperintensity volume (WMHV).