C
Cheng Li
Researcher at Peking University
Publications - 238
Citations - 49764
Cheng Li is an academic researcher from Peking University. The author has contributed to research in topics: Gene & Medicine. The author has an hindex of 63, co-authored 200 publications receiving 42539 citations. Previous affiliations of Cheng Li include University of California, Los Angeles & Tongji University.
Papers
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Journal ArticleDOI
Comparative analysis of the gut microbiota composition between knee osteoarthritis and Kashin-Beck disease in Northwest China
Yujie Ning,Minhan Hu,Yi Gong,Ruitian Huang,Ke Xu,Si-li Chen,Feiyu Zhang,Yanli Liu,Fei Chen,Yanhai Chang,Guanghui Zhao,Cheng Li,Rong Zhou,Mikko J. Lammi,Xiong Guo,Xi Wang +15 more
TL;DR: In this paper , the authors compared the gut microbiota structure between OA and KBD patients using 16S rDNA gene sequencing and found that the OA group was characterized by elevated Epsilonbacteraeota and Firmicutes levels, while the KBD group had higher Prevotella_9, Lactobacillus, Coprococcus_2, Senegalimassilia , and Holdemanella levels.
Journal ArticleDOI
Genetic Variants and Protein Alterations of Selenium- and T-2 Toxin-Responsive Genes Are Associated With Chondrocytic Damage in Endemic Osteoarthropathy
Yujie Ning,Minhan Hu,Jiayu Diao,Yi Gong,Ruitian Huang,Si-li Chen,Feiyu Zhang,Yanli Liu,Fei Chen,Pan Zhang,Guanghui Zhao,Yanhai Chang,K Xu,Rong Zhou,Cheng Li,Feng Zhang,Mikko J. Lammi,Xi Wang,Xirong Guo +18 more
TL;DR: This study sampled the cubital venous blood of 258 subjects including 129 sex-matched KBD patients and 129 healthy controls for SNP detection and verified significantly upregulated PPARG, ADAM12, SMAD3, and TIMP2 in KBD compared with OA and normal controls.
Journal ArticleDOI
Large Regions of Uniparental Disomy (UPD) Establish Clonal Hematopoietic Stem Cell Selection in a Subset of Myelodysplastic Syndrome (MDS) Patients with Normal Bone Marrow Cell Karyotypes.
Stefan Heinrichs,Rima V. Kulkarni,Carlos E. Bueso-Ramos,Mignon L. Loh,Ross L. Levine,Cheng Li,Donna Neuberg,Steve Kornblau,Jean Pierre J. Issa,D. Gary Gilliland,Elihu H. Estey,A. Thomas Look +11 more
TL;DR: SNP array and cytogenetic analysis are complementary methods for the identification of abnormal clones in MDS patients, each detecting overlapping but distinct subsets of patients.
Book ChapterDOI
Analysis of Acquired Genomic Copy Number Aberrations and Regions of Loss of Heterozygosity in Acute Myelogenous Leukemia Genomes Using Affymetrix SNP 6.0 Arrays and Supporting Software Tools
TL;DR: This guide should help the reader establish this powerful technology in the laboratory and aims to stimulate transition of SNP array profiling into clinical applications.
Journal ArticleDOI
Genome Wide Single Nucleotide Polymorphism Typing for Identification of Putative Minor Histocompatibility Antigens in Graft Versus Host Disease.
Ann Mullally,Cheng Li,Haesook T. Kim,Mehrdad Mohseni,Edwin P. Alyea,Joseph H. Antin,Robert J. Soiffer,Jerome Ritz +7 more
TL;DR: It is revealed that mismatch of non-synonymous cSNPs in the GVHD direction occurs at an appreciable frequency in sibling pairs consistent with the hypothesis that the number of mHA in humans is large.