Cheng Li

TL;DR: ChipInfo is designed for retrieving annotation information from online databases and organizing such information into easily interpretable tabular format outputs and enables users to independently update the information resource files of these software packages.

TL;DR: In this article, the authors used SNP 6.0 array-based genomic profiling of acquired copy number aberrations (aCNA) and copy neutral LOH (cnLOH) together with sequence analysis of recurrently mutated genes to characterize paired AML genomes.

TL;DR: It is demonstrated that YAP is a nucleocytoplasmic shuttling protein and its nuclear export is controlled by SET1A-mediated mono-methylation of YAP at K342, which disrupts the binding of Y AP to CRM1.

TL;DR: Using sc-itChIP-seq to profile H3K27ac, the earliest epigenetic priming event during the cell fate transition from naive to primed pluripotency is captured, and the basis for cell-type specific enhancer usage during the differentiation of bipotent cardiac progenitor cells into endothelial cells and cardiomyocytes is revealed.

TL;DR: Examples from patients with myeloid malignancies are used to demonstrate the superiority of matched tumor and normal DNA samples over multiple unpaired samples with respect to reducing false discovery rates in high-resolution single nucleotide polymorphism array analysis.