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Cheng Li
Researcher at Peking University
Publications - 238
Citations - 49764
Cheng Li is an academic researcher from Peking University. The author has contributed to research in topics: Gene & Medicine. The author has an hindex of 63, co-authored 200 publications receiving 42539 citations. Previous affiliations of Cheng Li include University of California, Los Angeles & Tongji University.
Papers
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Journal ArticleDOI
rRNA biogenesis regulates mouse 2C-like state by 3D structure reorganization of peri-nucleolar heterochromatin.
Hua Yu,Zhen Sun,Tianyu Tan,Hongru Pan,Jing Zhao,Ling Zhang,Jiayu Chen,Anhua Lei,Yuqing Zhu,Lang Chen,Yuyan Xu,Yaxin Liu,Ming Chen,Jinghao Sheng,Zhengping Xu,Pengxu Qian,Cheng Li,Shaorong Gao,George Q. Daley,Jin Zhang +19 more
TL;DR: In this article, the authors present evidence that nucleolar stress induced by interfering rRNA biogenesis can drive the 2-cell stage embryo-like (2C-like) program and induce an expanded 2Clike cell population in mouse embryonic stem (mES) cells.
Journal ArticleDOI
The Polyoma Virus Large T Binding Protein p150 Is a Transcriptional Repressor of c-MYC
Chang Kyoo Sung,Hyungshin Yim,Hongcang Gu,Dawei Li,Erik Andrews,Sekhar Duraisamy,Cheng Li,Ronny Drapkin,Ronny Drapkin,Thomas L. Benjamin +9 more
TL;DR: Analysis of data in The Cancer Genome Atlas shows negative correlations between SALL2 and c-MYC expression in four common solid tumor types.
Journal ArticleDOI
Transcriptionally inactive hepatitis B virus episome DNA preferentially resides in the vicinity of chromosome 19 in 3D host genome upon infection.
Dingbin Tang,Hanqing Zhao,Yumeng Wu,Bo Peng,Zhenchao Gao,Yinyan Sun,Jinzhi Duan,Yonghe Qi,Yunfei Li,Zhongmin Zhou,Guilan Guo,Yu Zhang,Cheng Li,Jianhua Sui,Wenhui Li +14 more
TL;DR: In this paper, the authors used chromosome conformation capture-based sequencing analysis and fluorescence in situ hybridization (FISH) to study covalently closed circular (ccc) DNA spatial localization in the 3D host genome.
Journal ArticleDOI
Identification of human leucocyte antigen (HLA)‐A*0201‐restricted cytotoxic T lymphocyte epitopes derived from HLA‐DOβ as a novel target for multiple myeloma
Yoon Joong Kang,Wanyong Zeng,Weihua Song,Bruce B. Reinhold,Jaewon Choi,Vladimir Brusic,Takuto Yamashita,Aditya Munshi,Cheng Li,Stephane Minvielle,Kenneth C. Anderson,Nikhil C. Munshi,Ellis L. Reinherz,Tetsuro Sasada,Tetsuro Sasada +14 more
TL;DR: Taken together, based on the physical presence on tumour cell surface and high immunogenicity, HLA‐DOB232–240 might be useful for developing a novel immunotherapy against MM.
Posted ContentDOI
Single-cell transcriptome profiling reveals neutrophil heterogeneity and orchestrated maturation during homeostasis and bacterial infection
Xiaohui Xie,Qiang Shi,Peng Wu,Xiaoyu Zhang,Xiaoyu Zhang,Xiaoyu Zhang,Hiroto Kambara,Hiroto Kambara,Jiayu Su,Jiayu Su,Jiayu Su,Hongbo Yu,Sheldon Park,Sheldon Park,Rongxia Guo,Qian Ren,Sudong Zhang,Yanfeng Xu,Leslie E. Silberstein,Leslie E. Silberstein,Tao Cheng,Cheng Li,Hongbo R. Luo,Hongbo R. Luo +23 more
TL;DR: A comprehensive single-cell resolution transcriptional landscape of mouse neutrophil maturation and fate decision under steady-state and bacterial infection conditions is provided, establishing a reference model and general framework for studying neutrophIL-related disease mechanisms, biomarkers, and therapeutic targets at single- cell resolution.