C
Chris J.L.M. Meijer
Researcher at VU University Amsterdam
Publications - 745
Citations - 83366
Chris J.L.M. Meijer is an academic researcher from VU University Amsterdam. The author has contributed to research in topics: Cervical cancer & Cervical intraepithelial neoplasia. The author has an hindex of 128, co-authored 733 publications receiving 78705 citations. Previous affiliations of Chris J.L.M. Meijer include VU University Medical Center & Academic Center for Dentistry Amsterdam.
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Journal ArticleDOI
Role of Epstein-Barr virus DNA load monitoring in prevention and early detection of post-transplant lymphoproliferative disease
Servi J. C. Stevens,Erik A M Verschuuren,Sandra A W M Verkuujlen,Adriaan J. C. van den Brule,Chris J.L.M. Meijer,Jaap M. Middeldorp +5 more
TL;DR: This review focuses on the clinical utility of EBV DNA load monitoring in the peripheral blood of transplant recipients using PCR and discusses the currently most-widely used techniques and their value and limitations in predicting and diagnosing PTLD.
Journal ArticleDOI
Repression of MAL tumour suppressor activity by promoter methylation during cervical carcinogenesis
Renée M Overmeer,Florianne E. Henken,Mariska Bierkens,Saskia M. Wilting,Ilse Timmerman,Chris J.L.M. Meijer,Peter J.F. Snijders,Renske D.M. Steenbergen +7 more
TL;DR: MAL gene silencing by promoter methylation is a frequent and biologically essential event in HPV‐induced cervical carcinogenesis and may provide a valuable diagnostic tool to improve the detection of CIN3, SCC, and AdCA.
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HPV DNA testing in population-based cervical screening (VUSA-Screen study): results and implications.
D.C. Rijkaart,Johannes Berkhof,F.J. van Kemenade,Veerle M.H. Coupé,Lawrence Rozendaal,Daniëlle A.M. Heideman,René H.M. Verheijen,Saskia Bulk,Wim M. Verweij,Peter J.F. Snijders,Chris J.L.M. Meijer +10 more
TL;DR: Primary hrHPV screening with cytology triage in women aged ⩾30 years is an effective way to stratify women on CIN3+ risk and seems a feasible alternative to cytological screening, however repeat cytology after 1 year is however necessary before returning women to routine screening.
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Cutting Edge: Polycomb Gene Expression Patterns Reflect Distinct B Cell Differentiation Stages in Human Germinal Centers
Frank M. Raaphorst,Folkert J. van Kemenade,Elly Fieret,Karien M. Hamer,David P. E. Satijn,Arie P. Otte,Chris J.L.M. Meijer +6 more
TL;DR: It is shown that human Pc-G expression patterns correlate with different B cell differentiation stages and that they reflect germinal center (GC) architecture, and a role for P c-G proteins in GC development is suggested.
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Methylation Analysis of the FAM19A4 Gene in Cervical Scrapes Is Highly Efficient in Detecting Cervical Carcinomas and Advanced CIN2/3 Lesions
L.M.A. de Strooper,Chris J.L.M. Meijer,J. Berkhof,Albertus T. Hesselink,Peter J.F. Snijders,Renske D.M. Steenbergen,Daniëlle A.M. Heideman +6 more
TL;DR: FAM19A4 is an attractive triage marker for hrHPV-positive women, with a high reassurance for the detection of cervical carcinoma and advanced CIN2/3 lesions.