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Chris J.L.M. Meijer

Researcher at VU University Amsterdam

Publications -  745
Citations -  83366

Chris J.L.M. Meijer is an academic researcher from VU University Amsterdam. The author has contributed to research in topics: Cervical cancer & Cervical intraepithelial neoplasia. The author has an hindex of 128, co-authored 733 publications receiving 78705 citations. Previous affiliations of Chris J.L.M. Meijer include VU University Medical Center & Academic Center for Dentistry Amsterdam.

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Human Papillomavirus Type–Specific 18-Month Risk of High-Grade Cervical Intraepithelial Neoplasia in Women with a Normal or Borderline/Mildly Dyskaryotic Smear

TL;DR: High-risk human papillomavirus (hrHPV) DNA testing is an increasingly used instrument in cervical cancer prevention along cervical cytology and warrants more aggressive management of HPV16/18–positive women compared with other hrHPV-positive women.
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Analysis of lymphoid and dendritic cells in human lymph node, tonsil and spleen. A study using monoclonal and heterologous antibodies.

TL;DR: In this paper, the distribution of lymphoid and dendritic cells in human reactive lymph nodes, tonsils and spleens was examined by means of an indirect immunoperoxydase technique, using a panel of monoclonal and heterologous antibodies.
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PAI-1 synthesis in the human hepatoma cell line HepG2 is increased by cytokines--evidence that the liver contributes to acute phase behaviour of PAI-1.

TL;DR: Results demonstrate that synthesis of PAI-1 by HepG2 cells is regulated by cytokines and implicate that the acute phase behaviour of PAi-1 in vivo at least in part may be due to an increased synthesis by the liver.
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p16(INK4a) immunostaining as an alternative to histology review for reliable grading of cervical intraepithelial lesions.

TL;DR: It is demonstrated that additive use of p16INK4a immunohistochemistry significantly improves the accuracy of grading CIN lesions by a single pathologist, equalling an expert consensus diagnosis.