C
Chris J.L.M. Meijer
Researcher at VU University Amsterdam
Publications - 745
Citations - 83366
Chris J.L.M. Meijer is an academic researcher from VU University Amsterdam. The author has contributed to research in topics: Cervical cancer & Cervical intraepithelial neoplasia. The author has an hindex of 128, co-authored 733 publications receiving 78705 citations. Previous affiliations of Chris J.L.M. Meijer include VU University Medical Center & Academic Center for Dentistry Amsterdam.
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Journal ArticleDOI
Development of a multiplex methylation-specific PCR as candidate triage test for women with an HPV-positive cervical scrape
Suzanne Snellenberg,Lise M.A. De Strooper,Albertus T. Hesselink,Chris J.L.M. Meijer,Peter J.F. Snijders,Daniëlle A.M. Heideman,Renske D.M. Steenbergen +6 more
TL;DR: Multiplex qMSP offers a promising approach for high-throughput diagnostic analysis of the methylation status of multiple genes, which after proper design and validation can be equally specific, sensitive and reproducible as its singleplex versions.
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Class II-associated invariant chain peptide expression on myeloid leukemic blasts predicts poor clinical outcome
Martine E.D. Chamuleau,Yuri Souwer,Yuri Souwer,Yuri Souwer,S. Marieke van Ham,Adri Zevenbergen,Theresia M. Westers,Johannes Berkhof,Chris J.L.M. Meijer,Arjan A. van de Loosdrecht,Gert J. Ossenkoppele +10 more
TL;DR: It is hypothesized that DR+/CLIP− AML blasts are able to present leukemia-specific antigens to CD4+ T helper cells initiating an effective and long-lasting antitumor response resulting in a prolonged disease-free survival.
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Clusterin: a protective mediator for ischemic cardiomyocytes?
Paul A.J. Krijnen,Saskia A. G. M. Cillessen,R. Manoe,A. Muller,Cees A. Visser,Chris J.L.M. Meijer,René J. P. Musters,C. E. Hack,Lucien A. Aarden,Hans W.M. Niessen +9 more
TL;DR: It is concluded that ischemia induces the upregulation of clusterin in ischemically challenged, but viable, cardiomyocytes and suggests that clusterin protects cardiomers against ischemic cell death via a complement-independent pathway.
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Incidence and survival rate of women with cervical cancer in the Greater Amsterdam area
TL;DR: The screening programme in The Netherlands as executed in the Greater Amsterdam area is associated with a decreased incidence and increased survival of patients with squamous cell carcinoma, but fails to detect (pre)malignant lesions of adenocarcinoma.
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Prevalence of human papillomavirus in women with invasive cervical carcinoma by HIV status in Kenya and South Africa.
Hugo De Vuyst,Gathari Ndirangu,Manivasan Moodley,Vanessa Tenet,Benson B. Estambale,Chris J.L.M. Meijer,Peter J.F. Snijders,Gary M. Clifford,Silvia Franceschi +8 more
TL;DR: The data suggest that current prophylactic HPV vaccines against HPV16 and 18 may prevent similar proportions of cervical SCC in HIV‐positive as in HIV-negative women provided that vaccine‐related protection is sustained after HIV infection.