C
Chris J.L.M. Meijer
Researcher at VU University Amsterdam
Publications - 745
Citations - 83366
Chris J.L.M. Meijer is an academic researcher from VU University Amsterdam. The author has contributed to research in topics: Cervical cancer & Cervical intraepithelial neoplasia. The author has an hindex of 128, co-authored 733 publications receiving 78705 citations. Previous affiliations of Chris J.L.M. Meijer include VU University Medical Center & Academic Center for Dentistry Amsterdam.
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Journal ArticleDOI
Direct immunosuppressive effects of EBV-encoded latent membrane protein 1.
D. F. Dukers,Pauline Meij,Marcel B.H.J. Vervoort,Wim Vos,Rik J. Scheper,Chris J.L.M. Meijer,Elisabeth Bloemena,Jaap M. Middeldorp +7 more
TL;DR: It is shown that nanogram amounts of purified recombinant LMP1 (rLMP1) strongly suppresses activation of T cells and suggests that EBV-positive tumor cells may actively secrete L MP1 and thus mediate immunosuppressive effects on tumor-infiltrating lymphocytes.
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Causes of Cervical Cancer in the Philippines: a Case-Control Study
Cora Ngelange,Nubia Muñoz,F. Xavier Bosch,Mario R. Festin,Judith Deacon,M. V. Jacobs,M. Santamaria,Chris J.L.M. Meijer,Jan M. M. Walboomers +8 more
TL;DR: It is shown that HPV is the central cause of adenocarcinoma/adenosquamous carcinoma of the uterine cervix and high parity, low socioeconomic status, and smoking were also associated with both types of cervical cancer.
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Codon modification of T cell receptors allows enhanced functional expression in transgenic human T cells
Kirsten B.J. Scholten,Duco Kramer,Esther W. M. Kueter,Marcus Graf,Thomas Schoedl,Chris J.L.M. Meijer,Marco W.J. Schreurs,Erik Hooijberg +7 more
TL;DR: Significant improvements are reported here in the functional expression of specific human TCRs that will hopefully expedite clinical application of TCR transfer-based immunotherapy.
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Tracing the origin of adenocarcinomas with unknown primary using immunohistochemistry: differential diagnosis between colonic and ovarian carcinomas as primary sites.
TL;DR: Most ovarian carcinomas, including the mucinous ones, can be discriminated with high probability from colonic carcinomas using a panel of three antibodies directed against CEA, cytokeratin 7, and vimentin, which appeared to be CK7 and CEA.
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Intra‐operative rapid diagnostic method based on CK19 mRNA expression for the detection of lymph node metastases in breast cancer
Mike Visser,Mehdi Jiwa,A. Horstman,Antoinette A. T. P. Brink,René Pol,Paul J. van Diest,Peter J.F. Snijders,Chris J.L.M. Meijer +7 more
TL;DR: The results indicate that OSNA‐CK19 can potentially be useful in an intra‐operative clinical setting to detect SN tumor involvement in breast cancer patients.