C
Christophe Klopp
Researcher at Institut national de la recherche agronomique
Publications - 219
Citations - 14274
Christophe Klopp is an academic researcher from Institut national de la recherche agronomique. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 44, co-authored 207 publications receiving 11088 citations. Previous affiliations of Christophe Klopp include University of Toulouse & Centre national de la recherche scientifique.
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Journal ArticleDOI
Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota
Matteo Serino,Elodie Luche,Sandra Grès,Audrey Baylac,Mathieu Bergé,Claire Cenac,Aurélie Waget,Pascale Klopp,Jason S. Iacovoni,Christophe Klopp,Jérôme Mariette,Olivier Bouchez,Jérôme Lluch,Françoise Ouarné,Pierre Monsan,Philippe Valet,Christine Roques,Jacques Amar,Anne Bouloumié,Vassilia Theodorou,Rémy Burcelin +20 more
TL;DR: The HFD-D gut microbial profile was associated with increased gut permeability linked to increased endotoxaemia and to a dramatic increase in cell number in the stroma vascular fraction from visceral white adipose tissue.
Journal ArticleDOI
An immune-related gene evolved into the master sex-determining gene in rainbow trout, Oncorhynchus mykiss.
Ayaka Yano,René Guyomard,Barbara Nicol,Elodie Jouanno,Edwige Quillet,Christophe Klopp,Cédric Cabau,Olivier Bouchez,Alexis Fostier,Yann Guiguen +9 more
TL;DR: It is demonstrated that master sex determinants can arise from the de novo evolution of genes that have not been previously implicated in sex differentiation through the demonstration that sdY is a novel vertebrate master sex-determining gene not related to any known sex-differentiating gene.
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D-GENIES: dot plot large genomes in an interactive, efficient and simple way.
TL;DR: D-GENIES is a standalone and web application performing large genome alignments using minimap2 software package and generating interactive dot plots, which enables users to sort query sequences along the reference, zoom in the plot and download several image, alignment or sequence files.
Journal ArticleDOI
Involvement of tissue bacteria in the onset of diabetes in humans: evidence for a concept
Jacques Amar,Matteo Serino,Céline Lange,Chantal Chabo,Jason S. Iacovoni,Stanislas Mondot,Patricia Lepage,Christophe Klopp,Jérôme Mariette,Olivier Bouchez,L. Perez,Michael Courtney,Michel Marre,Pascale Klopp,Olivier Lantieri,Joël Doré,Marie-Aline Charles,B. Balkau,Rémy Burcelin +18 more
TL;DR: 16S rDNA was shown to be an independent marker of the risk of diabetes, evidence for the concept that tissue bacteria are involved in the onset of diabetes in humans.
Journal ArticleDOI
Oak genome reveals facets of long lifespan.
Christophe Plomion,Jean-Marc Aury,Joelle Amselem,Thibault Leroy,Florent Murat,Sébastien Duplessis,Sébastien Faye,Nicolas Francillonne,Karine Labadie,Grégoire Le Provost,Isabelle Lesur,Jérôme Bartholomé,Patricia Faivre-Rampant,Annegret Kohler,Jean-Charles Leplé,Nathalie Chantret,Jun Chen,Anne Dievart,Tina Alaeitabar,Valérie Barbe,Caroline Belser,Hélène Bergès,Catherine Bodénès,Marie-Béatrice Bogeat-Triboulot,Marie-Lara Bouffaud,Benjamin Brachi,Emilie Chancerel,David Cohen,Arnaud Couloux,Corinne Da Silva,Carole Dossat,François Ehrenmann,Christine Gaspin,Jacqueline Grima-Pettenati,Erwan Guichoux,Arnaud Hecker,Sylvie Herrmann,Philippe Hugueney,Irène Hummel,Christophe Klopp,Céline Lalanne,Martin Lascoux,Eric Lasserre,Arnaud Lemainque,Marie-Laure Desprez-Loustau,Isabelle Luyten,Mohammed-Amin Madoui,Sophie Mangenot,Clemence Marchal,Florian Maumus,Jonathan Mercier,Célia Michotey,Olivier Panaud,Nathalie Picault,Nicolas Rouhier,Olivier Rué,Camille Rustenholz,Franck Salin,Marçal Soler,Marçal Soler,Mika T. Tarkka,Amandine Velt,Amy E. Zanne,Francis Martin,Patrick Wincker,Hadi Quesneville,Antoine Kremer,Jérôme Salse +67 more
TL;DR: Through this case study of oak, the accumulation and transmission of somatic mutations and the expansion of disease-resistance gene families in trees are demonstrated.