Daniela Rodriguez-Rincon

TL;DR: Using whole-genome analysis of a global collection of clinical isolates, it is shown that the majority of M. abscessus infections are acquired through transmission, potentially via fomites and aerosols, of recently emerged dominant circulating clones that have spread globally.

TL;DR: In this paper, the authors used whole-genome analysis of a global collection of clinical isolates to show that the majority of M. abscessus infections are acquired through transmission, potentially via fomites and aerosols, of recently emerged dominant circulating clones.

TL;DR: In this article, the authors defined key, generalizable steps involved in the pathogenic evolution of mycobacteria and showed that epigenetic modifiers, acquired through horizontal gene transfer, cause saltational increases in pathogenic potential of specific environmental clones.

TL;DR: The results expand knowledge with respect to the regulatory mechanisms of the MmpL family of proteins and a novel mechanism of drug resistance in this difficult-to-treat respiratory mycobacterial pathogen.

TL;DR: R RAND Europe evaluated how COG-UK delivered against its objectives, for example how it contributed to advancing scientific knowledge about SARS-CoV-2, informing public health decisions, and providing information that can be used to evaluate the effectiveness of vaccines and treatments.