D
Deepshikha Verma
Researcher at Colorado State University
Publications - 27
Citations - 1011
Deepshikha Verma is an academic researcher from Colorado State University. The author has contributed to research in topics: Mycobacterium abscessus & Medicine. The author has an hindex of 8, co-authored 19 publications receiving 711 citations. Previous affiliations of Deepshikha Verma include Virginia–Maryland Regional College of Veterinary Medicine & Council of Scientific and Industrial Research.
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Journal ArticleDOI
Emergence and spread of a human-transmissible multidrug-resistant nontuberculous mycobacterium.
Josephine M. Bryant,Josephine M. Bryant,Dorothy M Grogono,Dorothy M Grogono,Daniela Rodriguez-Rincon,Isobel Everall,Karen Brown,Karen Brown,Pablo Moreno,Deepshikha Verma,Emily Hill,Judith Drijkoningen,Peter H. Gilligan,Charles R. Esther,Peadar G. Noone,Olivia Giddings,Scott C. Bell,Scott C. Bell,Rachel Thomson,Claire E. Wainwright,Claire E. Wainwright,Chris Coulter,Sushil Pandey,Michelle Wood,Michelle Wood,Rebecca E Stockwell,Rebecca E Stockwell,Kay A. Ramsay,Kay A. Ramsay,Laura J. Sherrard,Timothy J. Kidd,Timothy J. Kidd,Nassib Jabbour,Graham R. Johnson,Luke D. Knibbs,Lidia Morawska,Peter D. Sly,Andrew Jones,Diana Bilton,Ian F. Laurenson,Michael Ruddy,Stephen Bourke,Ian C. J. W. Bowler,Stephen J Chapman,Andrew Clayton,Mairi Cullen,Owen J. Dempsey,Miles Denton,M. Desai,Richard J Drew,Frank Edenborough,Jason T. Evans,Jonathan Folb,Thomas Daniels,Helen Humphrey,Barbara Isalska,Søren Jensen-Fangel,Bodil Jönsson,Andrew M Jones,Terese L. Katzenstein,Troels Lillebaek,Gordon MacGregor,Sarah Mayell,Michael Millar,Deborah E. Modha,Edward F. Nash,C. O'Brien,Deirdre O'Brien,Chandra Ohri,Caroline S. Pao,Daniel Peckham,Felicity Perrin,Audrey Perry,Tania Pressler,Laura Prtak,Tavs Qvist,Ali Robb,Helen Rodgers,Kirsten Schaffer,Nadia Shafi,Jakko van Ingen,Martin Walshaw,Danie Watson,Noreen West,Joanna L. Whitehouse,Charles S. Haworth,Simon R. Harris,Diane J. Ordway,Julian Parkhill,R. Andres Floto,R. Andres Floto +90 more
TL;DR: Using whole-genome analysis of a global collection of clinical isolates, it is shown that the majority of M. abscessus infections are acquired through transmission, potentially via fomites and aerosols, of recently emerged dominant circulating clones that have spread globally.
Emergence and spread of a human-transmissible multidrug-resistant nontuberculous mycobacterium
Josephine M. Bryant,Dorothy M Grogono,Daniela Rodriguez-Rincon,Isobel Everall,Karen Brown,Pablo Moreno,Deepshikha Verma,E. Hill,J. Drijkoningen,Peter H. Gilligan,Charles R. Esther,Peadar G. Noone,Olivia Giddings,Scott C. Bell,Rachel Thomson,Claire E. Wainwright,Chris Coulter,Sushil Pandey,Michelle Wood,Rebecca E Stockwell,Kay A. Ramsay,Laura J. Sherrard,Timothy J. Kidd,Nassib Jabbour,Graham R. Johnson,Luke D. Knibbs,Lidia Morawska,Peter D. Sly,Alison Jones,Diana Bilton,Ian F. Laurenson,Michael Ruddy,Stephen Bourke,Ian C. J. W. Bowler,Stephen J Chapman,Andrew Clayton,M. Cullen,Owen J. Dempsey,Miles Denton,M. Desai,R. J. Drew,F. Edenborough,Jason T. Evans,Jonathan Folb,T. Daniels,H. Humphrey,B. Isalska,Søren Jensen-Fangel,Bodil Jönsson,Andrew Jones,Terese L. Katzenstein,Troels Lillebaek,Gordon MacGregor,S. Mayell,Michael Millar,Deborah E. Modha,Edward F. Nash,C. O'Brien,D. OBrien,Chandra Ohri,Caroline S. Pao,Daniel Peckham,Felicity Perrin,Audrey Perry,Tacjana Pressler,L. Prtak,Tavs Qvist,A. Robb,Helen Rodgers,K. Schaffer,Nadia Shafi,J. van Ingen,M. Walshaw,D. Watson,Noreen West,Joanna L. Whitehouse,Charles S. Haworth,Simon R. Harris,Diane J. Ordway,Julian Parkhill,R.A. Floto +80 more
TL;DR: In this paper, the authors used whole-genome analysis of a global collection of clinical isolates to show that the majority of M. abscessus infections are acquired through transmission, potentially via fomites and aerosols, of recently emerged dominant circulating clones.
Journal ArticleDOI
Stepwise pathogenic evolution of Mycobacterium abscessus
Josephine M. Bryant,Josephine M. Bryant,Karen Brown,Karen Brown,Sophie Burbaud,Isobel Everall,Isobel Everall,Juan Manuel Belardinelli,Daniela Rodriguez-Rincon,Dorothy M Grogono,Dorothy M Grogono,Chelsea Peterson,Deepshikha Verma,Ieuan E. Evans,Ieuan E. Evans,Christopher Ruis,Christopher Ruis,Aaron Weimann,Aaron Weimann,Divya Arora,Sony Malhotra,Sony Malhotra,Bridget P. Bannerman,Bridget P. Bannerman,Charlotte Passemar,Kerra Templeton,Gordon MacGregor,Kasim Jiwa,Andrew J. Fisher,Tom L. Blundell,Diane J. Ordway,Mary Jackson,Julian Parkhill,Julian Parkhill,R. Andres Floto,R. Andres Floto,R. Andres Floto +36 more
TL;DR: In this article, the authors defined key, generalizable steps involved in the pathogenic evolution of mycobacteria and showed that epigenetic modifiers, acquired through horizontal gene transfer, cause saltational increases in pathogenic potential of specific environmental clones.
Journal ArticleDOI
Clofazimine inhalation suspension for the aerosol treatment of pulmonary nontuberculous mycobacterial infections
Brandon Banaschewski,Deepshikha Verma,Lian J. Pennings,Matthew D. Zimmerman,Qihua Ye,Jake Gadawa,Véronique Dartois,Diane J. Ordway,Jakko van Ingen,Stefan Ufer,Kevin Stapleton,Thomas Hofmann +11 more
TL;DR: Clofazimine inhalation suspension is a well tolerated and effective novel therapeutic candidate for the treatment of NTM infections in mouse models and was shown to significantly improve bacterial elimination from the lungs of both acute and chronic NTM-infected mouse models.
Journal ArticleDOI
Truncated hemoglobin, HbN, is post-translationally modified in Mycobacterium tuberculosis and modulates host-pathogen interactions during intracellular infection.
Swati Arya,Deepti Sethi,Sandeep Singh,Mangesh Dattu Hade,Vijender Singh,Preeti Raju,Sathi Babu Chodisetti,Deepshikha Verma,Grish C. Varshney,Javed N. Agrewala,Kanak L. Dikshit +10 more
TL;DR: The involvement of HbN in modulating the host-pathogen interactions and immune system of the host apart from protecting the bacilli from nitrosative stress inside the activated macrophages, consequently driving cells toward increased infectivity and intracellular survival is suggested.