C
Cotton Seed
Researcher at Broad Institute
Publications - 42
Citations - 7389
Cotton Seed is an academic researcher from Broad Institute. The author has contributed to research in topics: Genome & Khovanov homology. The author has an hindex of 19, co-authored 40 publications receiving 4013 citations. Previous affiliations of Cotton Seed include Harvard University & Intel.
Papers
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Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries
Seyedeh M. Zekavat,Sanni Ruotsalainen,Robert E. Handsaker,Maris Alver,Jonathan M. Bloom,Timothy Poterba,Cotton Seed,Jason Ernst,Mark Chaffin,Jesse M. Engreitz,Gina M. Peloso,Ani Manichaikul,Chaojie Yang,Kathleen A. Ryan,Mao Fu,W. Craig Johnson,Michael Y. Tsai,Matthew J. Budoff,Vasan S. Ramachandran,L. Adrienne Cupples,Jerome I. Rotter,Stephen S. Rich,Wendy S. Post,Braxton D. Mitchell,Adolfo Correa,Andres Metspalu,James G. Wilson,Veikko Salomaa,Manolis Kellis,Mark J. Daly,Benjamin M. Neale,Steven A. McCarroll,Ida Surakka,Tõnu Esko,Andrea Ganna,Samuli Ripatti,Sekar Kathiresan,Pradeep Natarajan +37 more
TL;DR: Deep-coverage whole genome sequencing in 8392 individuals of European and African ancestry is used to discover and interpret both single-nucleotide variants and copy number (CN) variation associated with Lp(a), and finds that LPA risk genotypes confer greater relative risk for incident atherosclerotic cardiovascular diseases compared to directly measured LP(a).
Journal ArticleDOI
Addendum: The mutational constraint spectrum quantified from variation in 141,456 humans
Sanna Gudmundsson,Sanna Gudmundsson,Sanna Gudmundsson,Konrad J. Karczewski,Konrad J. Karczewski,Laurent C. Francioli,Laurent C. Francioli,Grace Tiao,Grace Tiao,Beryl B. Cummings,Beryl B. Cummings,Jessica Alföldi,Jessica Alföldi,Qingbo Wang,Qingbo Wang,Ryan L. Collins,Ryan L. Collins,Kristen M. Laricchia,Kristen M. Laricchia,Andrea Ganna,Andrea Ganna,Andrea Ganna,Daniel P. Birnbaum,Daniel P. Birnbaum,Laura D. Gauthier,Harrison Brand,Harrison Brand,Matthew Solomonson,Matthew Solomonson,Nicholas A. Watts,Nicholas A. Watts,Daniel R. Rhodes,Moriel Singer-Berk,Moriel Singer-Berk,Eleina M. England,Eleina M. England,Eleanor G. Seaby,Eleanor G. Seaby,Jack A. Kosmicki,Jack A. Kosmicki,Raymond K. Walters,Raymond K. Walters,Katherine Tashman,Katherine Tashman,Yossi Farjoun,Eric Banks,Timothy Poterba,Timothy Poterba,Arcturus Wang,Arcturus Wang,Cotton Seed,Cotton Seed,Nicola Whiffin,Jessica X. Chong,Kaitlin E. Samocha,Emma Pierce-Hoffman,Emma Pierce-Hoffman,Zachary Zappala,Zachary Zappala,Zachary Zappala,Anne H. O’Donnell-Luria,Eric Vallabh Minikel,Ben Weisburd,Monkol Lek,James S. Ware,James S. Ware,Christopher Vittal,Christopher Vittal,Irina M. Armean,Irina M. Armean,Louis Bergelson,Kristian Cibulskis,Kristen M. Connolly,Miguel Covarrubias,Stacey Donnelly,Steven Ferriera,Stacey Gabriel,Jeff Gentry,Namrata Gupta,Thibault Jeandet,Diane Kaplan,Christopher Llanwarne,Ruchi Munshi,Sam Novod,Nikelle Petrillo,David Roazen,Valentin Ruano-Rubio,Andrea Saltzman,Molly Schleicher,Jose Soto,Kathleen Tibbetts,Charlotte Tolonen,Gordon Wade,Michael E. Talkowski,Michael E. Talkowski,Benjamin M. Neale,Benjamin M. Neale,Mark J. Daly,Daniel G. MacArthur +98 more
Patent
An apparatus and method for an automatic thread-partition compiler
TL;DR: In this article, a thread-partition compiler is proposed to hide memory access latency through or by overlapping memory access with computations or with other memory accesses in a parallel multi-threaded architecture.
Posted ContentDOI
Systematic single-variant and gene-based association testing of 3,700 phenotypes in 281,850 UK Biobank exomes
Konrad J. Karczewski,Konrad J. Karczewski,Matthew Solomonson,Matthew Solomonson,Katherine R. Chao,Katherine R. Chao,Julia K. Goodrich,Julia K. Goodrich,Grace Tiao,Grace Tiao,Lu W,Lu W,Riley-Gillis Bm,Ellen A. Tsai,Hye In Kim,Zheng X,Rahimov F,Esmaeeli S,Jason Grundstad A,Mark Reppell,Jeff Waring,Jacob H,David Sexton,Paola G. Bronson,Xing Chen,Hu X,Jacqueline I. Goldstein,Jacqueline I. Goldstein,King D,King D,Vittal C,Vittal C,Timothy Poterba,Timothy Poterba,Duncan S. Palmer,Duncan S. Palmer,Claire Churchhouse,Claire Churchhouse,Daniel P. Howrigan,Daniel P. Howrigan,Wei Zhou,Wei Zhou,Nicholas A. Watts,Nicholas A. Watts,Katrina Nguyen,Katrina Nguyen,Nguyen H,Nguyen H,Mason C,Farnham C,Charlotte Tolonen,Laura D. Gauthier,Namrata Gupta,Daniel G. MacArthur,Heidi L. Rehm,Heidi L. Rehm,Cotton Seed,Cotton Seed,Anthony A. Philippakis,Mark J. Daly,Justin W. Davis,Heiko Runz,Melissa R. Miller,Benjamin M. Neale,Benjamin M. Neale +64 more
TL;DR: In this paper, the full manuscript has been temporarily withdrawn by the authors upon request from UK Biobank and results supporting this manuscript remain valid and can be found at https://genebass.org.
Posted Content
Computations of the Lipshitz-Sarkar Steenrod Square on Khovanov Homology
TL;DR: In this paper, a space-level refinement of Khovanov homology has been proposed, which induces a Steenrod square operation on Khovanshitz-Sarkar homology.