Chaojie Yang

TL;DR: This research presents a novel probabilistic approach that allows us to assess the importance of knowing the carrier and removal status of canine coronavirus, as a source of infection for other animals.

TL;DR: In this article, the authors used deep-coverage whole genome sequencing in 8392 individuals of European and African ancestry to discover and interpret both single-nucleotide variants and copy number (CN) variation associated with Lp(a).

TL;DR: In this article , a cross-ancestry GWAS meta-analyses of 110,182 patients who have had a stroke (five ancestries, 33% non-European) and 1,503,898 control individuals, identify association signals for stroke and its subtypes at 89 (61 new) independent loci: 60 in primary inverse-variance-weighted analyses and 29 in secondary meta-regression and multitrait analyses.

TL;DR: Deep-coverage whole genome sequencing in 8392 individuals of European and African ancestry is used to discover and interpret both single-nucleotide variants and copy number (CN) variation associated with Lp(a), and finds that LPA risk genotypes confer greater relative risk for incident atherosclerotic cardiovascular diseases compared to directly measured LP(a).

TL;DR: This study performs whole genome sequence analysis of lung function and COPD in a multi-ethnic sample of 11,497 participants from population- and family-based studies, and 8499 individuals from COPD-enriched studies in the NHLBI Trans-Omics for Precision Medicine Program.