Csaba P. Kovesdy

TL;DR: Studying this condition and its potential causes and consequences may lead to a better understanding of the pathophysiology of metabolic syndrome and diabetes mellitus in the CKD population and in many other individuals with chronic disease states associated with wasting syndrome that can confound the natural history of diabetes.

TL;DR: Mechanisms by which hypothyroidism adversely affects cardiovascular health are discussed; the prognostic implications of hypothyrodesis, thyroid hormone alterations and exogenous thyroid hormone replacement in CKD and ESRD are examined; and areas of uncertainty related to the interplay between hypothyrogenism, cardiovascular disease and kidney disease requiring further investigation are identified.

TL;DR: In chronic kidney disease, anemia and disordered iron homeostasis are prevalent and associated with significant adverse consequences as discussed by the authors, and new data have accrued from basic research, epidemiological studies, and randomized trials that warrant a re-examination of previous recommendations.

TL;DR: It is found that absent, mild, or moderate/severe constipation associate with higher risk of incident CKD and ESRD and with progressive eGFR decline, independent of known risk factors.

TL;DR: Compared with reference measures of LBM, equations using serum creatinine level, MAMC, or handgrip strength and demographic variables can estimate LBM accurately in long-term hemodialysis patients.