C
Cyrus Cooper
Researcher at Southampton General Hospital
Publications - 1961
Citations - 248928
Cyrus Cooper is an academic researcher from Southampton General Hospital. The author has contributed to research in topics: Population & Osteoporosis. The author has an hindex of 204, co-authored 1869 publications receiving 206782 citations. Previous affiliations of Cyrus Cooper include University of Oxford & University of York.
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Journal ArticleDOI
The natural history of radiographic knee osteoarthritis: a fourteen-year population-based cohort study.
K M Leyland,Deborah J. Hart,Muhammad Javaid,Andrew Judge,Amit Kiran,Anushka Soni,L Goulston,Cyrus Cooper,Tim D. Spector,Nigel K Arden,Nigel K Arden +10 more
TL;DR: The results showed relatively low rates for the incidence and progression of radiographic knee OA; more than half of all subjects had no radiographic evidence of knees OA over a 15-year period of time.
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The epidemiology of osteonecrosis: findings from the GPRD and THIN databases in the UK
TL;DR: This study provides further perspective on the descriptive epidemiology of ON as well as selecting potential risk factors for ON using two health record databases in the UK: the General Practice Research Database and The Health Improvement Network.
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The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis
Ana M. Valdes,Gert De Wilde,Sally Doherty,Rik Lories,Frances L. Vaughn,Laura L Laslett,Rose A. Maciewicz,Anushka Soni,Deborah J. Hart,Weiya Zhang,Kenneth Muir,Elaine M. Dennison,Margaret Wheeler,Paul E. Leaverton,Cyrus Cooper,Cyrus Cooper,Tim D. Spector,Flavia M. Cicuttini,Victoria Chapman,Graeme Jones,Nigel K Arden,Nigel K Arden,Michael Doherty +22 more
TL;DR: A genotype involved in lower peripheral pain sensitivity is significantly associated with a decreased risk of painful knee OA, which indicates a role for the pro-nociceptive gene TRPV1 in genetic susceptibility to symptomatic knee Oa, which may also be influenced by a role by this molecule in cartilage function.
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Long-term outcome following total knee arthroplasty: a controlled longitudinal study
J Cushnaghan,James E. Bennett,Isabel Reading,Peter Croft,P Byng,Ken Cox,Paul Dieppe,David Coggon,Cyrus Cooper +8 more
TL;DR: Improvements in physical function following TKA for osteoarthritis are sustained beyond 5 years, and there seems no justification for withholding TKA from obese patients solely on the grounds of their body mass index.
Journal ArticleDOI
Knee disorders in the general population and their relation to occupation.
TL;DR: Results suggest that hospital referral for knee symptoms is influenced to some extent by patients’ occupational activities, and playing soccer is confirmed as a strong risk factor for knee cartilage injury.