C
Cyrus Cooper
Researcher at Southampton General Hospital
Publications - 1961
Citations - 248928
Cyrus Cooper is an academic researcher from Southampton General Hospital. The author has contributed to research in topics: Population & Osteoporosis. The author has an hindex of 204, co-authored 1869 publications receiving 206782 citations. Previous affiliations of Cyrus Cooper include University of Oxford & University of York.
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Journal ArticleDOI
Effect of smoking on physical and cognitive capability in later life: a multicohort study using observational and genetic approaches
Teri-Louise North,Tom Palmer,Sarah J Lewis,Rachel Cooper,Chris Power,Alison Pattie,John M. Starr,Ian J. Deary,Richard M. Martin,Avan Aihie Sayer,Meena Kumari,Cyrus Cooper,Mika Kivimäki,Diana Kuh,Yoav Ben-Shlomo,Ian N. M. Day +15 more
TL;DR: The observational analysis supports the hypothesis that smoking is detrimental to physical and cognitive capability and further studies are needed for a suitably powered MR approach.
Journal ArticleDOI
Gestational Vitamin D Supplementation Leads to Reduced Perinatal RXRA DNA Methylation: Results From the MAVIDOS Trial
Elizabeth M Curtis,N Krstic,E Cook,Stefania D'Angelo,Sarah Crozier,Rebecca J Moon,Robert Murray,Emma Garratt,P Costello,Jane K. Cleal,Brogan Ashley,Nick Bishop,Stephen Kennedy,Aris T. Papageorghiou,Inez Schoenmakers,Robert Fraser,S V Gandhi,Ann Prentice,M Kassim Javaid,Hazel Inskip,Keith M. Godfrey,Christopher G. Bell,Karen A. Lillycrop,Cyrus Cooper,Nicholas C. Harvey +24 more
TL;DR: New evidence is provided that maternal gestational supplementation with cholecalciferol leads to altered perinatal epigenetic marking, informing mechanistic understanding of early life mechanisms related to maternal vitamin D status, epigenetic marks, and bone development.
Journal ArticleDOI
Dupuytren's contracture and occupational exposure to hand-transmitted vibration.
Keith T Palmer,Stefania D'Angelo,Holly E. Syddall,Michael J. Griffin,Cyrus Cooper,David Coggon +5 more
TL;DR: The findings suggest that risk of Dupuytren's contracture is more than doubled in men with high levels of weekly exposure to HTV.
Journal ArticleDOI
A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus
Ling Oei,Yi-Hsiang Hsu,Yi-Hsiang Hsu,Unnur Styrkarsdottir,Bert H.J. Eussen,Annelies de Klein,Marjolein J. Peters,Bjarni V. Halldorsson,Bjarni V. Halldorsson,Ching-Ti Liu,Nerea Alonso,Stephen Kaptoge,Gudmar Thorleifsson,Göran Hallmans,Lynne J. Hocking,L. B. Husted,Karen A. Jameson,Marcin Kruk,Joshua R. Lewis,Joshua R. Lewis,Millan S. Patel,Serena Scollen,Olle Svensson,Stella Trompet,Natasja M. van Schoor,Kun Zhu,Kun Zhu,Brendan M. Buckley,Cyrus Cooper,Ian Ford,David Goltzman,Jesús González-Macías,Bente L. Langdahl,William D. Leslie,Paul Lips,Roman S. Lorenc,José M. Olmos,Ulrika Pettersson-Kymmer,David M. Reid,José A. Riancho,P. Eline Slagboom,Carmen Garcia-Ibarbia,Thorvaldur Ingvarsson,Thorvaldur Ingvarsson,Hrefna Johannsdottir,Robert Luben,Carolina Medina-Gomez,Pascal P. Arp,Kannabiran Nandakumar,Stefan T Palsson,Gunnar Sigurdsson,Joyce B. J. van Meurs,Yanhua Zhou,Albert Hofman,J. Wouter Jukema,Huibert A. P. Pols,Richard L. Prince,Richard L. Prince,L. Adrienne Cupples,Christian R. Marshall,Christian R. Marshall,Dalila Pinto,Daisuke Sato,Stephen W. Scherer,Stephen W. Scherer,Jonathan Reeve,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,David Karasik,J. Brent Richards,J. Brent Richards,Kari Stefansson,Kari Stefansson,André G. Uitterlinden,Stuart H. Ralston,John P. A. Ioannidis,Douglas P. Kiel,Fernando Rivadeneira,Karol Estrada,Karol Estrada,Karol Estrada +80 more
TL;DR: The results suggest that deletions in the 6p25.1 locus may predispose to higher risk of fracture in a subset of populations of European origin; larger and geographically restricted studies will be needed to confirm this regional association.
Journal ArticleDOI
Syndrome of symptomatic adult acetabular dysplasia (SAAD syndrome)
TL;DR: The high prevalence of acetabular dysplasia in subjects presenting with hip pain to primary care and its relationship with radiographic osteoarthritis (OA) of the hip suggests that Dysplasia itself may be an important cause of hip pain.