Daisy Hjelmqvist

TL;DR: These findings provide a mechanistic link between EVs and vascular dysfunction during malaria infection and show that EVs are efficiently internalized by endothelial cells, where the miRNA-Argonaute 2 complexes modulate target gene expression and barrier properties.

TL;DR: These studies highlight the interplay between host and parasite lipid metabolism and provide a comprehensive analysis of P. falciparum lipids with candidate pathways for drug discovery efforts.

TL;DR: This work functionally demonstrate an analogous host‐targeting pathway involving organellar staging prior to secretion in the related bovine parasite, Babesia bovis, a parasite that destroys the PVM shortly after invasion.

TL;DR: A capillary‐based platform for cell isolation with single‐cell RNA‐sequencing to transcriptionally profile 165 single infected red blood cells during the intra‐erythrocytic developmental cycle (IDC) and a gene signature is uncovered that can successfully discriminate between developing asexual and sexual stage parasites at cellular resolution.

TL;DR: The anti-peroxyl radical quality of two aqueous rooibos infusions and solutions of their most abundant glycosylated polyphenols was evaluated and it was observed that the artificial infusions showed greater antioxidant quality than the latter infusions, reaching values close to those reported for tea infusions.