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Daniela Bruni
Researcher at Paris Descartes University
Publications - 19
Citations - 4966
Daniela Bruni is an academic researcher from Paris Descartes University. The author has contributed to research in topics: Cancer & Immune system. The author has an hindex of 13, co-authored 18 publications receiving 2591 citations. Previous affiliations of Daniela Bruni include Maynooth University & Pierre-and-Marie-Curie University.
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Journal ArticleDOI
Approaches to treat immune hot, altered and cold tumours with combination immunotherapies
Jérôme Galon,Daniela Bruni +1 more
TL;DR: A panel of therapeutic strategies to use, combine and develop to treat hot, altered and cold tumours is provided and the impact of combination therapy on the immune response to convert an immune cold into a hot tumour will be discussed.
Journal ArticleDOI
International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study
Franck Pagès,Bernhard Mlecnik,Florence Marliot,Gabriela Bindea,Gabriela Bindea,Gabriela Bindea,Fang Shu Ou,Carlo Bifulco,Alessandro Lugli,Inti Zlobec,Tilman T. Rau,Martin D. Berger,Iris D. Nagtegaal,Elisa Vink-Börger,Arndt Hartmann,Carol Geppert,Julie Kolwelter,Susanne Merkel,Robert Grützmann,Marc Van den Eynde,Anne Jouret-Mourin,Alex Kartheuser,Daniel Léonard,Christophe Remue,Julia Y. Wang,Julia Y. Wang,Prashant Bavi,Michael H.A. Roehrl,Michael H.A. Roehrl,Michael H.A. Roehrl,Pamela S. Ohashi,Linh T. Nguyen,Seong Jun Han,Heather L. MacGregor,Sara Hafezi-Bakhtiari,Bradly G. Wouters,Giuseppe Masucci,Emilia Andersson,Eva Zavadova,Michal Vocka,Jan Spacek,Lubos Petruzelka,Bohuslav Konopasek,Pavel Dundr,Helena Skalova,Kristyna Nemejcova,Gerardo Botti,Fabiana Tatangelo,Paolo Delrio,Gennaro Ciliberto,Michele Maio,Luigi Laghi,Fabio Grizzi,Tessa Fredriksen,Tessa Fredriksen,Tessa Fredriksen,Bénédicte Buttard,Bénédicte Buttard,Bénédicte Buttard,Mihaela Angelova,Mihaela Angelova,Mihaela Angelova,Angela Vasaturo,Angela Vasaturo,Angela Vasaturo,Pauline Maby,Pauline Maby,Pauline Maby,Sarah E. Church,Helen K. Angell,Lucie Lafontaine,Lucie Lafontaine,Lucie Lafontaine,Daniela Bruni,Daniela Bruni,Daniela Bruni,Carine El Sissy,Nacilla Haicheur,Amos Kirilovsky,Anne Berger,Christine Lagorce,Jeffrey P. Meyers,Christopher Paustian,Zipei Feng,Carmen Ballesteros-Merino,Jeroen R. Dijkstra,Carlijn van de Water,Shannon van Vliet,Nikki Knijn,Ana Maria Mușină,Dragos Viorel Scripcariu,Boryana Popivanova,Mingli Xu,Tomonobu Fujita,Shoichi Hazama,Nobuaki Suzuki,Hiroaki Nagano,Kiyotaka Okuno,Toshihiko Torigoe,Noriyuki Sato,Tomohisa Furuhata,Ichiro Takemasa,Kyogo Itoh,P. Patel,Hemangini H. Vora,Birva Shah,Jayendrakumar B. Patel,Kruti N. Rajvik,Shashank J. Pandya,Shilin N. Shukla,Yili Wang,Guanjun Zhang,Yutaka Kawakami,Francesco M. Marincola,Paolo A. Ascierto,Daniel J. Sargent,Bernard A. Fox,Bernard A. Fox,Jérôme Galon,Jérôme Galon,Jérôme Galon +120 more
TL;DR: The immunoscore provides a reliable estimate of the risk of recurrence in patients with colon cancer and supports the implementation of the consensus Immunoscore as a new component of a TNM-Immune classification of cancer.
Journal ArticleDOI
The immune contexture and Immunoscore in cancer prognosis and therapeutic efficacy.
TL;DR: The authors advocate the need to assess a combination of immune determinants and the importance of evaluating the functional status of specific cell populations to increase prognostic and/or predictive power.
Journal ArticleDOI
Evolution of Metastases in Space and Time under Immune Selection.
Mihaela Angelova,Bernhard Mlecnik,Angela Vasaturo,Gabriela Bindea,Tessa Fredriksen,Lucie Lafontaine,Bénédicte Buttard,Erwan Morgand,Daniela Bruni,Anne Jouret-Mourin,Catherine Hubert,Alex Kartheuser,Yves Humblet,Michele Ceccarelli,Najeeb Syed,Francesco M. Marincola,Davide Bedognetti,Marc Van den Eynde,Marc Van den Eynde,Jérôme Galon +19 more
TL;DR: A parallel selection model of metastatic progression, where branched evolution could be traced back to immune-escaping clones is proposed, which could inform the understanding of cancer dissemination and the development of immunotherapeutics.
Journal ArticleDOI
Tumor Immunology and Tumor Evolution: Intertwined Histories
Jérôme Galon,Daniela Bruni +1 more
TL;DR: It is argued for the importance of revising clinical stratification systems to include immune parameters so as to address the immediate need for improved prognostic and/or predictive information to guide clinical decisions.